Propargyl-PEG3-amine
- CAS No.
- 932741-18-9
- Chemical Name:
- Propargyl-PEG3-amine
- Synonyms
- Alkyne-PEG3-NH2;HC≡C-CH2-PEG3-NH2;Propyne-PEG3-amine;PROPARGYL-PEG3-NH2;Propargyl-PEG3-azide;Propargyl-PEG3-amine;Azido-PEG3-propargyl;3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)prop-1-yne;1-Propyne, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-
- CBNumber:
- CB43062621
- Molecular Formula:
- C9H15N3O3
- Molecular Weight:
- 213.24
- MDL Number:
- MFCD20720810
- MOL File:
- 932741-18-9.mol
Propargyl-PEG3-amine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P839893 | Propargyl-PEG3-Amine | 932741-18-9 | 10mg | $65 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1724 | Propargyl-PEG3-amine | 932741-18-9 | 100mg | $449 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | POL0002521 | PROPARGYL-PEG3-AZIDE 95.00% | 932741-18-9 | 5MG | $501.99 | 2021-12-16 | Buy |
| Apolloscientific | BIPG1728 | Propargyl-PEG3-azide | 932741-18-9 | 250mg | $546 | 2021-12-16 | Buy |
| Chemenu | CM327857 | 2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanamine 95%+ | 932741-18-9 | 10g | $937 | 2021-12-16 | Buy |
Propargyl-PEG3-amine Chemical Properties,Uses,Production
Uses
Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Biological Activity
Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Propargyl-PEG3-amine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5743 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32433 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| R&D Scientific Inc. | +1-2266000236 | sales@rdscientific.com | Canada | 1864 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9895 | 58 |
View Lastest Price from Propargyl-PEG3-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Propargyl-PEG3-N3
932741-18-9
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. | |
 |
2024-02-13 | Propargyl-PEG3-azide
932741-18-9
|
US $1800.00 / g | 1g | 95 | 1 Kg | R&D Scientific Inc. |
-
- Propargyl-PEG3-N3
932741-18-9
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
-
- Propargyl-PEG3-azide
932741-18-9
- US $1800.00 / g
- 95
- R&D Scientific Inc.
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