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N-Carbethoxy-4-piperidone

N-Carbethoxy-4-piperidone structure

CAS No.: 29976-53-2

Chemical Name:: N-Carbethoxy-4-piperidone

Synonyms: ETHYL 4-OXOPIPERIDINE-1-CARBOXYLATE;1-ETHOXYCARBONYL-4-PIPERIDONE;Loratadine EP IMpurity H;N-CARBOETHOXY-4-PIPERIDONE;N-ETHOXYCARBONYL-4-PIPERIDONE;LUBE-007;NSC 139022;AURORA KA-3057;N-Carbethoxypiperidone;carbethoxy-4-piperidone

CBNumber:: CB4332907

Molecular Formula:: C8H13NO3

Molecular Weight:: 171.19

MDL Number:: MFCD00006188

MOL File:: 29976-53-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:19:14

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N-Carbethoxy-4-piperidone Properties

Boiling point	95-98 °C (1 mmHg)
Density	1.135 g/mL at 25 °C (lit.)
vapor pressure	0.2-0.37Pa at 20-25℃
refractive index	n20/D 1.475(lit.)
Flash point	190 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Liquid
pka	-1.59±0.20(Predicted)
color	Clear colorless to pale yellow
PH	4.6 (H2O, 20℃)(saturated solution)
Water Solubility	slightly soluble
BRN	640967
InChI	1S/C8H13NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h2-6H2,1H3
InChIKey	LUBGFMZTGFXIIN-UHFFFAOYSA-N
SMILES	CCOC(=O)N1CCC(=O)CC1
LogP	0 at 20℃ and pH6.5-6.7
CAS DataBase Reference	29976-53-2(CAS DataBase Reference)
FDA UNII	7H5JX1S259
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280-P305+P351+P338-P337+P313

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Hazard Codes

Xn,Xi

Risk Statements

36/38-22-36/37/38-20/21/22

Safety Statements

23-24/25-37/39-26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29333999

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2

REACH Registrations

Active

NFPA 704

	2
1		0

N-Carbethoxy-4-piperidone price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0000605	Loratadine impurity H European Pharmacopoeia (EP) Reference Standard	29976-53-2	60 mg	$164	2026-04-30	Buy
Sigma-Aldrich	153737	Ethyl 4-oxo-1-piperidinecarboxylate 98%	29976-53-2	10g	$22.8	2026-04-30	Buy
Sigma-Aldrich	PHR2313	Loratadine impurity H PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial	29976-53-2	100MG	$593	2026-04-30	Buy
Sigma-Aldrich	153737	Ethyl 4-oxo-1-piperidinecarboxylate 98%	29976-53-2	50g	$109	2026-04-30	Buy
TCI Chemical	E0403	1-Ethoxycarbonyl-4-piperidone >97.0%(GC)	29976-53-2	25g	$36	2024-03-01	Buy

Product number	Packaging	Price	Buy
Y0000605	60 mg	$164	Buy
153737	10g	$22.8	Buy
PHR2313	100MG	$593	Buy
153737	50g	$109	Buy
E0403	25g	$36	Buy

N-Carbethoxy-4-piperidone Chemical Properties,Uses,Production

Chemical Properties

clear colorless to pale yellow colored liquid

Uses

N-Carbethoxy-4-piperidone (Loratadine EP Impurity H) is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. It is also an impurity of Loratadine (L469575).

Uses

Ethyl 4-oxo-1-piperidinecarboxylate (1-carbethoxy-4-piperidone) was used to prepare tertiary alcohols.

N-Carbethoxy-4-piperidone synthesis

Synthesis of N-Carbethoxy-4-piperidone from 1,3-Piperidinedicarboxylic acid, 4-oxo-, 1,3-diethyl ester

N-Carbethoxy-4-piperidone Preparation Products And Raw materials

Raw materials

Penfluridol

Preparation Products

4-(2-Keto-1-benzimidazolinyl)piperidine N-phenylpiperidin-4-amine 4-(4-Fluoro-phenyl)-piperidin-4-ol hydrochloride Ethyl 4-amino-1-piperidinecarboxylate AKOS USSH-4110751

1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-methoxy-, ethyl ester ethyl 4-hydroxy-4-(2-(2-hydroxyethyl)phenyl)piperidine-1-carboxylate 1-Piperidinecarboxylicacid,4-amino-4-cyano-,ethylester(9CI) Ethyl 2-amino-3-carbamoyl-4,7-dihydro-5H-thieno[2,3-c]-pyridine-6-carboxylate ethyl (3S,4R)-4-amino-3-methoxypiperidine-1-carboxylate

ethyl 4-(2,3-difluoro-6-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)-4-hydroxypiperidine-1-carboxylate Ethyl 4-hydroxypiperidine-1-carboxylate

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N-Carbethoxy-4-piperidone Spectrum

N-Carbethoxy-4-piperidone(29976-53-2)MS N-Carbethoxy-4-piperidone(29976-53-2)¹HNMR N-Carbethoxy-4-piperidone(29976-53-2)¹³CNMR N-Carbethoxy-4-piperidone(29976-53-2)IR1 N-Carbethoxy-4-piperidone(29976-53-2)Raman

29976-53-2(N-Carbethoxy-4-piperidone )Related Search:

Ethyl acrylate N-Carbobenzyloxyglycine Ethyl acetate 4-Piperidinone Ethylparaben

RESMETHRIN Ethylbenzene Haloperidol Ethyl cellulose tert-Butyl cyanoacetate

1-Acetyl-2-imidazolidinone N-(tert-Butoxycarbonyl)-4-piperidone Ethanol 11,11'-(Piperazine-1,4-diyl)-bis-8-chloro-5H-dibenze[b,e][1,4]-diazepine 1-FMOC-4-PIPERIDONE

1-Cbz-4-Piperidone Diethyl ether N-Boc-Nortropinone

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1-PIPERIDINECARBOXYLIC ACID, 4-OXO-, ETHYL ESTER 4-Oxo-1-piperidinecarboxylic acid ethyl ester N-Carbithoxy-4-Piperidone 1-Ethoxycarbonyl-4-Piperidone N-Carbethoxy-4-Hydroxy Piperidine N-Carbethoxypiperidone 1-ETHOXYCARBONYL-4-PIPERIDONE 97+% N-Carbethoxy-4-Piperidone99% N-Carbethoxy-4-piperidon carbethoxy-4-piperidone 4-Oxo-N-piperidinecarboxylic acid ethyl ester N-Carbethoxy-4-piperidone, 98.5+% 4-Oxopiperidine-N-carboxylic acid ethyl ester Ethyl 4-Piperidone-N-carboxylic acid 1-Carbethoxy-4-piperidone, 1-Ethoxycarbonyl-4-piperidone N-Carbethoxy-4-piperidone /1-PIPERIDINECARBOXYLIC ACID, 4-OXO-, ETHYL ESTER N-Ethoxycarbonyl-4-piperidinone NSC 139022 1-Carbethoxy-4-piperidone Ethyl 4-Oxo-1-piperidinecarboxylate 4-Oxo-1-piperidinecarboxylic Acid Ethyl Ester N-ETHOXYCARBONYL-4-PIPERIDONE FOR SYNTHE 1-(Ethoxycarbonyl)-4-oxopiperidine Ethyl 4-oxo-1-piperidinecarbo LUBE-007 1-Ethoxycarbonyl-4-piperidone,99% N-Ethoxycarbonyl-4-piperidone for synthesis N-CARBETHOXY-4-PIPERIDONE AURORA KA-3057 ETHYL 4-PIPERIDONE-1-CARBOXYLATE ETHYL 4-PIPERIDONE-N-CARBOXYLATE ETHYL 4-OXO-1-PIPERIDINECARBOXYLATE 4-PIPERIDONE-1-CARBOXYLIC ACID ETHYL ESTER 4-PIPERIDONE-N-CARBOXYLIC ACID ETHYL ESTER 4-OXO-PIPERIDINE-1-CARBOXYLIC ACID ETHYL ESTER 1-CARBETHOXY-4-PIPERIDONE 1-Ethoxycarbonyl-4-piperidone> N-methoxyethoxy -4- piperidone N-Carbethoxy-4-piperidone(NCP) N-Carbethoxy-4-piperidone, puriss, 98% N-Carbethoxy-4-piperidone, 10 mM in DMSO 1-Ethoxycarbonyl-4-piperidone, 95% N-Carbethoxy-4-piperidone (Loratadine Impurity) Desloratadine EP Impurity H Loratadine Impurity 8(Loratadine EP Impurity H) 1-ETHOXYCARBONYL-4-PIPERIDONE ETHYL 4-OXOPIPERIDINE-1-CARBOXYLATE Loratadine EP IMpurity H N-CARBOETHOXY-4-PIPERIDONE N-ETHOXYCARBONYL-4-PIPERIDONE 29976-53-2 299767-53-2 29976-53-3 29976-52-3 2079879-75-2 C8H13NO3 KETONE Heterocyclic Building Blocks Piperidones Building Blocks Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals