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1-Cbz-4-Piperidone

1-Cbz-4-Piperidone structure

CAS No.: 19099-93-5

Chemical Name:: 1-Cbz-4-Piperidone

Synonyms: BENZYL 4-OXOPIPERIDINE-1-CARBOXYLATE;N-BENZYLOXYCARBONYL-4-PIPERIDONE;N-CBZ-4-PIPERIDONE;1-CBZ-4-piperidinone;1-Z-4-PIPERIDONE;BENZYL 4-OXO-1-PIPERIDINECARBOXYLATE;Cbz-4-piperidone;1-N-CBZ-4-PIPERIDONE;1-CARBOBENZOXY-4-PIPERIDONE;N-Cbz-piperidone

CBNumber:: CB0110956

Molecular Formula:: C13H15NO3

Molecular Weight:: 233.26

MDL Number:: MFCD00673144

MOL File:: 19099-93-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:22:42

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1-Cbz-4-Piperidone Properties

Melting point	38-41°C
Boiling point	114-140 °C/0.25 mmHg (lit.)
Density	1.172 g/mL at 25 °C (lit.)
refractive index	n20/D 1.542(lit.)
Flash point	>110 °C
storage temp.	Sealed in dry,2-8°C
solubility	Chloroform, Dichloromethane, Ethyl Acetate, Methanol
form	Solid or Lliquid
pka	-1.63±0.20(Predicted)
Specific Gravity	1.185
color	White to pale yellow
BRN	1533716
InChI	InChI=1S/C13H15NO3/c15-12-6-8-14(9-7-12)13(16)17-10-11-4-2-1-3-5-11/h1-5H,6-10H2
InChIKey	VZOVOHRDLOYBJX-UHFFFAOYSA-N
SMILES	N1(C(OCC2=CC=CC=C2)=O)CCC(=O)CC1
CAS DataBase Reference	19099-93-5(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H412

Precautionary statements

P264-P270-P273-P301+P312-P501

PPE

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Hazard Codes

Risk Statements

36/37/38

Safety Statements

23-24/25-36-26-37/39

WGK Germany

HS Code

29333990

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral
Aquatic Chronic 3

NFPA 704

	1
2		0

1-Cbz-4-Piperidone price More Price(54)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	464643	1-Z-4-Piperidone 99%	19099-93-5	5ml	$76	2025-07-31	Buy
Sigma-Aldrich	464643	1-Z-4-Piperidone 99%	19099-93-5	25ml	$177	2025-07-31	Buy
Sigma-Aldrich	13635	1-Z-4-Piperidone purum, ≥95.0% (HPLC)	19099-93-5	10ml	$109	2022-05-15	Buy
Sigma-Aldrich	13635	1-Z-4-Piperidone purum, ≥95.0% (HPLC)	19099-93-5	50mL	$423	2022-05-15	Buy
TCI Chemical	B3643	Benzyl 4-Oxo-1-piperidinecarboxylate >98.0%(GC)	19099-93-5	5g	$34	2024-03-01	Buy

Product number	Packaging	Price	Buy
464643	5ml	$76	Buy
464643	25ml	$177	Buy
13635	10ml	$109	Buy
13635	50mL	$423	Buy
B3643	5g	$34	Buy

1-Cbz-4-Piperidone Chemical Properties, Uses, Production

Chemical Properties

Colourless Oil

Uses

Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.3

General Description

1-Cbz-4-Piperidone is the starting material in biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol condensation reactions.

1-Cbz-4-Piperidone synthesis

Synthesis of 1-Cbz-4-Piperidone from Benzyl chloroformate

1-Cbz-4-Piperidone Preparation Products And Raw materials

Raw materials

1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid 8-(Benzyloxycarbonyl)-1,4-dioxa-8-azaspiro[4.5]decane cyclohexylmethyl chloroformate 1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-[[(trifluoroMethyl)sulfonyl]oxy]-, phenylMethyl ester N-(Benzyloxycarbonyloxy)succinimide

Benzyl chloroformate Benzyl 4-hydroxy-1-piperidinecarboxylate 4-Hydroxypiperidine 4,4-Piperidinediol hydrochloride

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Preparation Products

2-Piperidone Ethyl 1-Cbz-5-oxoazepane-4-carboxylate 1-Piperidinecarboxylic acid, 4-[(2-methoxyethyl)amino]-, phenylmethyl ester

Properties, preparation and application of 1-cbz-4-piperidone
1-cbz-4-piperidone plays an important role in many fields. For example, in the field of medicine, it is often used to reduce p....
Jul 29,2022

1-Cbz-4-Piperidone Spectrum

1-(Benzyloxycarbonyl)-4-piperidinone(19099-93-5)¹HNMR 1-(Benzyloxycarbonyl)-4-piperidinone(19099-93-5)IR

19099-93-5 ( 1-Cbz-4-Piperidone) Related Search:

1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid Benzyl benzoate 4-Piperidinone N-Carbobenzyloxyglycine 2-Piperidone

N-Carbethoxy-4-piperidone 4,4-Piperidinediol hydrochloride tert-Butyl carbazate Thalidomide DROPERIDOL

Benzyl alcohol Haloperidol Benzyl bromide Trimethoprim Ethyl N- Cbz -piperidine-4-carboxylate

4-Carboxymethoxy-piperidine-1-carboxylic acid benzyl ester Diphenoxylate 1-Cbz-2-phenyl-piperidin-4-one

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1-(BENZYLOXYCARBONYL)-4-PIPERIDINONE 1-CARBOBENZOXY-4-PIPERIDONE 1-N-CBZ-4-PIPERIDONE PIPERIDIN-4-ONE, CBZ PROTECTED N-CBZ-4-PIPERIDONE N-BENZYLOXYCARBONYLPIPERIDIN-4-ONE N-BENZYLOXYCARBONYLPIPERIDONE 1-PIPERIDINECARBOXYLICACID,4-OXO-,PHENYLMETHYLESTER BENZYL 4-OXO-1-PIPERIDINECARBOXYLATE, 99 % Benzyl 4-oxo-1-piperazinecarboxylate N-Benzyloxycarbonyl-4-Pipridone N-Benzyloxycarbonyl-4-piperidone, 98+% 1-CBZ-4-PIPERIDONE N-Benzyloxycarbonyl-4-piperido 1-N-Cbz-4-Oxo-piperidine 1-Benzyloxycarbonyl-4-piperidone, 98+% 1-Benzyloxycarbonyl-4-oxopiperidine Piperidin-4-one, N-CBZ prote Piperidin-4-one, N-CBZ protected 97% 1-(Benzyloxycarbonyl)-4-piperidinone, 1-Cbz-4-Piperidone, Benzyl 4-oxo-1-piperidinecarboxylate 1-(Benzyloxycarbonyl)piperidine-4-one N-Cbz-piperidone Piperidin-4-one, N-CBZ protected benzyl 4-o×opiperidine-1-carbo×ylate 1-Cbz-Piperidin-4-one 1-Carbobenzoxy-4-piperidone 1-Cbz-4-piperidone 4-Oxo-1-piperidinecarboxylic Acid Benzyl Ester 1-Benzyloxycarbonyl-4-piperidine 1-CBZ-4-piperidinone 1-(Benzyloxycarbonyl)piperidin-4-one, Benzyl 4-oxopiperidine-1-carboxylate, 1-(Benzyloxycarbonyl)-4-oxopiperidine 1-Cbz-piperidin-4-one, 95+% N-Benzyloxycarbonyl-4-piperidone Synoyms Benzyl 4-oxo-1-piperazinecarboxylate 1-Z-4-Piperidone purum, >=95.0% (HPLC) 1-Benzyloxycarbonyl-4-piperidone,96% BENZYL 4-OXOPIPERAZINE-1-CARBOXYLATE 4-OXO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER Benzyl 4-Oxo-1-piperidinecarboxylate > 1-Cbz-4-Piperidone,>98% N-Benzyloxycarbonyl-4-piperidone 1-Cbz-4-Piperidone N-CBZ-4-piperidone N-CBZ-4 N-benzoxy carbonyl -4- piperidone 1-Benzyloxycarbonyl-4-piperidine 4-Oxo-1-piperidinecarboxylic Acid Benzyl Ester High Quality 1-Cbz-4-Piperidone benzyl 4-oxopiperidine-1-carboxylate 19099-93-5 N-Cbz-4-Piperidone CAS 19099-93-5 N-CBZ-4-piperidone 1-(Benzyloxycarbonyl)-4-piperidinone Pharmaceutical Chemical N-Cbz-4-Piperidone CAS 19099-93-5 1-(Benzyloxycarbonyl)-4-piperidinone 1-(Benzyloxycarbonyl)-4-piperidinone/N-Benzyloxycarbonyl-4-piperidone 1-(Benzyloxycarbonyl)-4-piperidinonev 1-benzyloxycarbonyl-piperidin-4-one 1-Benzyloxy-4-piperidone 1-(Benzyloxycarbonyl)-4-piperidinone, 95% 1-Z-4-PIPERIDONE BENZYL 4-OXOPIPERIDINE-1-CARBOXYLATE BENZYL 4-OXO-1-PIPERIDINECARBOXYLATE Cbz-4-piperidone N-BENZYLOXYCARBONYL-4-PIPERIDONE 19099-93-5