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4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride structure

CAS No.: 109806-71-5

Chemical Name:: 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride

Synonyms: Cetirizine -EP-Imp-G;Levocetirizine Impurity G;Levocetirizine Impurity 6;(R)-2-(4-((4-chlorophenyl);4-Chlorobisphenylmethylphenidate;2-[4-{Chlorophenyl}Phenylmethyl]-1-;CETIRIZINE EP IMPURITY G (FREE BASE);Cetirizine EP Impurity G Hydrochloride;Levocetirizine Hydrochloride Impurity G;4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol

CBNumber:: CB4334224

Molecular Formula:: C19H23ClN2O

Molecular Weight:: 330.85

MDL Number:: MFCD12870433

MOL File:: 109806-71-5.mol

MSDS File:: SDS

Last updated:2026-09-12 18:52:45

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4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride Properties

Boiling point	205-208 °C(Press: 0.1 Torr)
Density	1.191±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Ethyl Acetate (Slightly), Methanol (Slightly)
form	Solid
pka	14.96±0.10(Predicted)
color	White to Off-White
Stability	Very Hygroscopic
InChI	InChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2
InChIKey	ZJQSBXXYLQGZBR-UHFFFAOYSA-N
SMILES	N1(CCO)CCN(C(C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1
CAS DataBase Reference	109806-71-5(CAS DataBase Reference)
FDA UNII	PGV947X9B1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS05
Signal word	Danger
Hazard statements	H314-H302-H318
Precautionary statements	P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	232706	4-[(4-Chlorophenyl)Phenylmethyl]-1-Piperazineethanol Dihydrochloride 99+% (HPLC) ≥99%(HPLC)	109806-71-5	1g	$229	2026-06-03	Buy
Usbiological	232706	4-[(4-Chlorophenyl)Phenylmethyl]-1-Piperazineethanol Dihydrochloride 99+% (HPLC) ≥99%(HPLC)	109806-71-5	5g	$508	2026-06-03	Buy
Usbiological	232706	4-[(4-Chlorophenyl)Phenylmethyl]-1-Piperazineethanol Dihydrochloride 99+% (HPLC) ≥99%(HPLC)	109806-71-5	25g	$1700	2026-06-03	Buy
Biosynth	FC53582	4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride	109806-71-5	0.25g	$900	2026-06-04	Buy
Biosynth	FC53582	4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride	109806-71-5	0.1g	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
232706	1g	$229	Buy
232706	5g	$508	Buy
232706	25g	$1700	Buy
FC53582	0.25g	$900	Buy
FC53582	0.1g	$900	Buy

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride Chemical Properties, Uses, Production

Chemical Properties

Off-White Solid

Uses

2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106).

Uses

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride synthesis

Synthesis of 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride from 4-Chlorobenzhydrol

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride Preparation Products And Raw materials

Raw materials

4-Chlorobenzophenone Calcium chloride 2-Bromoethanol Toluene Sodium borohydride

Triethylamine Piperazine 1,4-Dioxane Tetrahydrofuran Benzene

Dichloromethane Isopropyl alcohol Thionyl chloride 1-(4-Chlorobenzhydryl)piperazine

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Preparation Products

1-Piperazineacetaldehyde Cetirizine

4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride Suppliers

Global Suppliers ( 100)

Supplier	Tel	Email	Country	ProdList	Advantage
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16307	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Hunan HuaTeng Pharmaceutical Co., Ltd.,	400-8592883 15367835770	sales@huatengsci.com	China	5869	58
Nanjing Chalf-Pharm Technology Co., Ltd.	025-57018978 18251899859	sales@chalf-pharm.com	China	5855	50
Chizhou Kailong Import and Export Trade Co., Ltd.		xg01_gj@163.com	China	9413	50
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Shanghai CR Corporation Limited	13917420128 13062833949	fred.wen@crcorporation.cn	China	9775	58

Supplier	Advantage
Nanjing Chemlin Chemical Co., Ltd	64
Chemsky (shanghai) International Co.,Ltd	60
BOC Sciences	65
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Hunan HuaTeng Pharmaceutical Co., Ltd.,	58
Nanjing Chalf-Pharm Technology Co., Ltd.	50
Chizhou Kailong Import and Export Trade Co., Ltd.	50
BOC Sciences	65
Amadis Chemical Company Limited	58
Shanghai CR Corporation Limited	58

109806-71-5 (4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride) Related Search:

Ethanol Levocetirizine Hydrochloride Impurity F Acetic acid, 2-[2-[2-[4-[(4- chlorophenyl)phenylMethyl]-1-piperazinyl]ethoxy]ethoxy]- 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride 4-[(4-chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride (intermediate of cetirizine dihydrochloride)

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Levocetirizine

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2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL 2-[4-{Chlorophenyl}Phenylmethyl]-1- 2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol Levocetirizine Impurity G 4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone 1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]- (R)-2-(4-((4-chlorophenyl) Levocetirizine Impurity 6 Cetirizine -EP-Imp-G Cetirizine EP Impurity G Hydrochloride 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol Cetirizine Impurity 15 Monomer （Cetirizine EP Impurity G Monomer ） 4-Chlorobisphenylmethylphenidate Levocetirizine Hydrochloride Impurity G 2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethanol? (Cetirizine Impurity） 4-(p-Chloro-alpha-phenylbenzyl)-1-piperazineethanol 2-[4-([alpha]-phenyl-p-chloro-benzyl)piperazin-1-yl]ethanol 4-(p-Chloro-a-phenylbenzyl)-1-piperazineethanol 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORID CETIRIZINE EP IMPURITY G (FREE BASE) Cetirizine EP Impurity G (Cetirizine USP Related Compound G (Free Form), Levocetirizine EP Impurity H) Cetirizine Hydrochloride EP Impurity G free base 109806-71-5 (intermediate of cetirizine dihydrochloride)