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ChemicalBook >> CAS DataBase List >>{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Structure
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester structure
CAS No.
1807521-06-7
Chemical Name:
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
Synonyms
Ph-Bis(C1-N-(C2-NH-Boc)2);{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester;tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate;10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester
CBNumber:
CB43363807
Molecular Formula:
C36H64N6O8
Molecular Weight:
708.93
MDL Number:
MFCD28142457
MOL File:
1807521-06-7.mol
Last updated:2025-04-17 18:22:24
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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Properties

Boiling point 775.5±60.0 °C(Predicted)
Density 1.093±0.06 g/cm3(Predicted)
pka 11.79±0.46(Predicted)

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0116042 Ph-Bis(C1-N-(C2-NH-Boc)2) ≥98% 1807521-06-7 25mg $297 2026-06-04 Buy
ChemScene CS-0116042 Ph-Bis(C1-N-(C2-NH-Boc)2) ≥98% 1807521-06-7 50mg $445 2026-06-04 Buy
ChemScene CS-0116042 Ph-Bis(C1-N-(C2-NH-Boc)2) ≥98% 1807521-06-7 100mg $689 2026-06-04 Buy
ChemScene CS-0116042 Ph-Bis(C1-N-(C2-NH-Boc)2) ≥98% 1807521-06-7 250mg $1240 2026-06-04 Buy
Activate Scientific AS280557 1-(Boc-amino)-2-[(4-{[Bis-(2-(Boc-amino)-ethyl)-amino]-methyl}-benzyl)-(2-(Boc-amino)-ethyl)-amino]-ethane 96% 1807521-06-7 100mg $463 2026-06-04 Buy
Product number Packaging Price Buy
CS-0116042 25mg $297 Buy
CS-0116042 50mg $445 Buy
CS-0116042 100mg $689 Buy
CS-0116042 250mg $1240 Buy
AS280557 100mg $463 Buy

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Chemical Properties, Uses, Production

Uses

Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

Alkyl-Chain

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Shanghai Huici Pharmaceutical Technology Co., LTD 133-31922809 19372841038 lixing@pharmahuici.com China 853 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38900 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Aladdin Scientific tp@aladdinsci.com United States 50089 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 info@chemextension.com China 42052 58
Supplier Advantage
Jinan elephant international trading co., LTD 58
TargetMol Chemicals Inc. 58
Zhengzhou Akem Chemical Co., Ltd 58
Shanghai Huici Pharmaceutical Technology Co., LTD 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 58
Jilin Chinese Academy of Sciences-yanshen Technology 58
TargetMol Chemicals Inc. 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Aladdin Scientific 58
Jilin Chinese Academy of Sciences-yanshen Technology 58

1807521-06-7 ({2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester) Related Search:

Tert-butyl N-[2-(benzylaMino)ethyl]carbaMate N1,N1'-(1,4-phenylenebis(methylene))bis(N1-(2-aminoethyl)ethane-1,2-diamine) HCl salt N-(2-Boc-aminoethyl)-N-benzylethanolamine 1-N-Benzyl-1-N-methyl-2-Boc-ethane-1,2-diamine 2-[benzyl(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]acetic acid
tert-Butyl (2-(benzylaMino)ethyl)carbaMate hydrochloride

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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate Ph-Bis(C1-N-(C2-NH-Boc)2) 10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester 1807521-06-7