ChemicalBook >> CAS DataBase List >>(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid

CAS No.
203640-27-1
Chemical Name:
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid
Synonyms
S 3304, 10 mM in DMSO;R-3-(1H-Indol-3-yl)-2-(5-(p-tolyleth ynyl)thiophene-2;S 3304,Inhibitor,inhibit,S3304,MMP,S-3304,Matrix metalloproteinases;D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]-;(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid;(R)-3-(1H-Indol-3-yl)-2-(5-p-tolylethynyl-thiophene-2-sulfonylamino)-propionic acid;(2R)-3-(1H-indol-3-yl)-2-{5-[2-(4-methylphenyl)ethynyl]thiophene-2-sulfonamido}propanoic acid;(2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-methylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid
CBNumber:
CB43369157
Molecular Formula:
C24H20N2O4S2
Molecular Weight:
464.56
MDL Number:
MOL File:
203640-27-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Properties

Boiling point 745.7±70.0 °C(Predicted)
Density 1.47±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Aqueous Base (Slightly), DMSO (Slightly)
form Solid
pka 3.29±0.10(Predicted)
color Pale Beige to Light Beige
FDA UNII BK459F050X

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-S450405-5MG S 3304 203640-27-1 5mg $549 2026-06-03 Buy
TRC TRC-S450405-1MG S 3304 203640-27-1 1mg $186 2026-06-03 Buy
TRC TRC-S450405-10MG S 3304 203640-27-1 10mg $637 2026-06-03 Buy
ChemScene CS-0027075 S 3304 99.75% 203640-27-1 5mg $152 2026-06-04 Buy
ChemScene CS-0027075 S 3304 99.75% 203640-27-1 10mg $242 2026-06-04 Buy
Product number Packaging Price Buy
TRC-S450405-5MG 5mg $549 Buy
TRC-S450405-1MG 1mg $186 Buy
TRC-S450405-10MG 10mg $637 Buy
CS-0027075 5mg $152 Buy
CS-0027075 10mg $242 Buy

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Chemical Properties,Uses,Production

Description

S-3304 is a sulfonamide derivative that acts as a matrix metalloproteinase inhibitor.

Uses

S 3304, is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9.

in vivo

In vivo pharmacologic studies have shown that the oral administration of S 3304, at a dose range of 20 to 200 mg/kg, inhibits angiogenesis, artificially induced in mice by the dorsal air-sac method. Similar oral doses of S 3304 result in potent inhibition of metastatic lung colonization of Lewis murine lung carcinoma injected via tail vein and liver metastasis of C-1H human colon cancer implanted into the spleen[1].

IC 50

MMP-9

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Suppliers

Global( 50)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8058 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Wuxi Asia Peptide Biotechnology Limited Company 0510-83583050 13771062561 willsun@peptide-search.com China 6713 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 sales@uhnshanghai.com China 1983 58
Kanghua (Shanghai) New Drug Development Co., Ltd. 021-61263370 18516560301 xingli@glbiochem.com China 5637 58
Shanghai Jifeng Biotechnology Co., Ltd. 021-61263377 15023907684 15800684150@163.com China 7994 58

View Lastest Price from (R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
S 3304 pictures 2026-08-08 S 3304
203640-27-1
$68.00-188.00 98.09% 10g TargetMol Chemicals Inc.
  • S 3304 pictures
  • S 3304
    203640-27-1
  • $68.00-188.00
  • 98.09%
  • TargetMol Chemicals Inc.

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Spectrum

(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid R-3-(1H-Indol-3-yl)-2-(5-(p-tolyleth ynyl)thiophene-2 (2R)-3-(1H-indol-3-yl)-2-{5-[2-(4-methylphenyl)ethynyl]thiophene-2-sulfonamido}propanoic acid (2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-methylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]- (R)-3-(1H-Indol-3-yl)-2-(5-p-tolylethynyl-thiophene-2-sulfonylamino)-propionic acid S 3304,Inhibitor,inhibit,S3304,MMP,S-3304,Matrix metalloproteinases S 3304, 10 mM in DMSO 203640-27-1