(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid
- CAS No.
- 203640-27-1
- Chemical Name:
- (R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid
- Synonyms
- S 3304, 10 mM in DMSO;R-3-(1H-Indol-3-yl)-2-(5-(p-tolyleth ynyl)thiophene-2;S 3304,Inhibitor,inhibit,S3304,MMP,S-3304,Matrix metalloproteinases;D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]-;(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid;(R)-3-(1H-Indol-3-yl)-2-(5-p-tolylethynyl-thiophene-2-sulfonylamino)-propionic acid;(2R)-3-(1H-indol-3-yl)-2-{5-[2-(4-methylphenyl)ethynyl]thiophene-2-sulfonamido}propanoic acid;(2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-methylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid
- CBNumber:
- CB43369157
- Molecular Formula:
- C24H20N2O4S2
- Molecular Weight:
- 464.56
- MDL Number:
- MOL File:
- 203640-27-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 745.7±70.0 °C(Predicted) |
|---|---|
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 3.29±0.10(Predicted) |
| color | Pale Beige to Light Beige |
| FDA UNII | BK459F050X |
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-S450405-5MG | S 3304 | 203640-27-1 | 5mg | $549 | 2026-06-03 | Buy |
| TRC | TRC-S450405-1MG | S 3304 | 203640-27-1 | 1mg | $186 | 2026-06-03 | Buy |
| TRC | TRC-S450405-10MG | S 3304 | 203640-27-1 | 10mg | $637 | 2026-06-03 | Buy |
| ChemScene | CS-0027075 | S 3304 99.75% | 203640-27-1 | 5mg | $152 | 2026-06-04 | Buy |
| ChemScene | CS-0027075 | S 3304 99.75% | 203640-27-1 | 10mg | $242 | 2026-06-04 | Buy |
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Chemical Properties,Uses,Production
Description
S-3304 is a sulfonamide derivative that acts as a matrix metalloproteinase inhibitor.
Uses
S 3304, is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9.
in vivo
In vivo pharmacologic studies have shown that the oral administration of S 3304, at a dose range of 20 to 200 mg/kg, inhibits angiogenesis, artificially induced in mice by the dorsal air-sac method. Similar oral doses of S 3304 result in potent inhibition of metastatic lung colonization of Lewis murine lung carcinoma injected via tail vein and liver metastasis of C-1H human colon cancer implanted into the spleen[1].
IC 50
MMP-9
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai GL Peptide Ltd. | +86-21-61263310 13764994101 | fisherwang@glschina.com | China | 8058 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Wuxi Asia Peptide Biotechnology Limited Company | 0510-83583050 13771062561 | willsun@peptide-search.com | China | 6713 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 1983 | 58 |
| Kanghua (Shanghai) New Drug Development Co., Ltd. | 021-61263370 18516560301 | xingli@glbiochem.com | China | 5637 | 58 |
| Shanghai Jifeng Biotechnology Co., Ltd. | 021-61263377 15023907684 | 15800684150@163.com | China | 7994 | 58 |





