ARS-1323
- CAS No.
- 1698024-73-5
- Chemical Name:
- ARS-1323
- Synonyms
- CPD2015;ARS-1323;ARS-1323 (ARS1323);ARS-1323, 10 mM in DMSO;ARS1323;ARS 1323;ARS-1323;Inhibitor,Ras,ARS1323,ARS 1323,inhibit,ARS-1323;2-Propen-1-one, 1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
- CBNumber:
- CB43369788
- Molecular Formula:
- C21H17ClF2N4O2
- Molecular Weight:
- 430.84
- MDL Number:
- MOL File:
- 1698024-73-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
ARS-1323 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | YSC02473 | ARS-1620 | 1698024-73-5 | 10mg | $851.7 | 2026-06-05 | Buy |
| Biosynth | YSC02473 | ARS-1620 | 1698024-73-5 | 25mg | $1388.5 | 2026-06-05 | Buy |
| Biosynth | YSC02473 | ARS-1620 | 1698024-73-5 | 50mg | $2221.5 | 2026-06-05 | Buy |
| ChemScene | CS-0035015 | ARS-1323 99.67% | 1698024-73-5 | 5mg | $173 | 2026-06-04 | Buy |
| ChemScene | CS-0035015 | ARS-1323 99.67% | 1698024-73-5 | 10mg | $282 | 2026-06-04 | Buy |
ARS-1323 Chemical Properties, Uses, Production
Uses
ARS-1620, is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.
Definition
ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.
IC 50
KRas G12C
ARS-1323 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Biopharmaleader Co., Ltd. | +86 18721201413 | sales@biopharmaleader.com | China | 1711 | 58 |
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3057 | 58 | |
| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3307 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
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