N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester)
- CAS No.
- 2086689-00-9
- Chemical Name:
- N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester)
- Synonyms
- MUN 89009;N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester);2-(Azido-PEG3-amido)-1,3-bis(t-butyl ester)
- CBNumber:
- CB43373688
- Molecular Formula:
- C26H48N4O10
- Molecular Weight:
- 576.69
- MDL Number:
- MFCD30723287
- MOL File:
- 2086689-00-9.mol
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114956 | N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) ≥98% | 2086689-00-9 | 100mg | $178 | 2026-06-04 | Buy |
| ChemScene | CS-0114956 | N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) ≥98% | 2086689-00-9 | 250mg | $319 | 2026-06-04 | Buy |
| ChemScene | CS-0114956 | N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) ≥98% | 2086689-00-9 | 1g | $826 | 2026-06-04 | Buy |
| BroadPharm | bp-23476 | 2-(Azido-PEG3-amido)-1,3-bis(t-butyl ester) 98% | 2086689-00-9 | 100MG | $320 | 2026-05-24 | Buy |
| BroadPharm | bp-23476 | 2-(Azido-PEG3-amido)-1,3-bis(t-butyl ester) 98% | 2086689-00-9 | 250MG | $650 | 2026-05-24 | Buy |
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) Chemical Properties, Uses, Production
Description
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is developed as a branched PEG linker with a terminal azide group and two t-butyl esters. The azide group enables PEGylation via Click Chemistry. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.
Uses
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Minhan Pharmaceutical Technology Co., Ltd. | 17612188245 | 2816925681@qq.com | China | 8316 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1246 | 58 |
| CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD | 17882285575 | 1276966012@qq.com | China | 399 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Yanfen Biochemical Technology Co.,LTD | 13611955358 15002190549 | yanfen2023@126.com | China | 2573 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
