Diglycolic anhydride
- CAS No.
- 4480-83-5
- Chemical Name:
- Diglycolic anhydride
- Synonyms
- 1,4-DIOXANE-2,6-DIONE;4-Maleimidobutyric acid hydrazide hydrochloride;SKL267;p-Dioxane-2,6-dione;digylcolic anhydride;DIGLYCOLIC ANHYDRIDE;Oxydiacetic anhydride;1,4-DIOXINE-2,6-DIONE;DiglycolicAnhydride>Diglycolicanhydride,95%
- CBNumber:
- CB4361550
- Molecular Formula:
- C4H4O4
- Molecular Weight:
- 116.07
- MDL Number:
- MFCD00006677
- MOL File:
- 4480-83-5.mol
- MSDS File:
- SDS
| Melting point | 92-93 °C (lit.) |
|---|---|
| Boiling point | 240-241 °C (lit.) |
| Density | 1.4230 |
| refractive index | 1.5800 (estimate) |
| Flash point | 240-241°C |
| storage temp. | Store below +30°C. |
| solubility | Soluble in chloroform. |
| form | Crystalline Powder, Crystals or Needles |
| color | White to pale cream |
| Sensitive | Moisture Sensitive |
| BRN | 112527 |
| Stability | Hygroscopic, Moisture Sensitive |
| InChI | 1S/C4H4O4/c5-3-1-7-2-4(6)8-3/h1-2H2 |
| InChIKey | PIYNUZCGMLCXKJ-UHFFFAOYSA-N |
| SMILES | O=C1COCC(=O)O1 |
| CAS DataBase Reference | 4480-83-5(CAS DataBase Reference) |
| FDA UNII | RKE2JJ6VPJ |
| NIST Chemistry Reference | 1,4-Dioxane-2,6-dione(4480-83-5) |
| UNSPSC Code | 12352115 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| RIDADR | 2923 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29189090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
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Diglycolic anhydride price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D103705 | Diglycolic anhydride technical grade, 90% | 4480-83-5 | 25g | $187 | 2026-04-30 | Buy |
| Sigma-Aldrich | D103705 | Diglycolic anhydride technical grade, 90% | 4480-83-5 | 5g | $57.2 | 2023-06-20 | Buy |
| TCI Chemical | D2308 | Diglycolic Anhydride >95.0%(T) | 4480-83-5 | 25g | $77 | 2026-04-30 | Buy |
| TCI Chemical | D2308 | Diglycolic Anhydride >98.0%(T) | 4480-83-5 | 100g | $256 | 2026-04-30 | Buy |
| Biosynth | FD11051 | Diglycolic anhydride | 4480-83-5 | 0.5kg | $649 | 2026-06-04 | Buy |
Diglycolic anhydride Chemical Properties, Uses, Production
Chemical Properties
white to off-white
Uses
Diglycolic anhydride is used in the preparation of N,N-diethyldiglycollamsaeure by reacting with diethylamine. It is an useful bio chemical for proteomics research.
Synthesis
50.01 g of diglycolic acid was dissolved in 140 mL of acetic anhydride, Heated to 145 ℃, Add 5 drops of phosphoric acid as initiator, And the mixture was refluxed for 2 hours. After the reaction was stopped, Most acetic anhydride was removed by rotary evaporation at 80 ℃. Approximately 100 mL of liquid was obtained,300 mL of toluene was added. Stirring, and allowed to stand for 10 hours. Vacuum filtration to give 38.89g colourless to white Diglycolic anhydride crystals. The yield was 90%.
Diglycolic anhydride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Surui Chemical Co., LTD | 15833970389 15833970389 | sjzkhhg@126.com | China | 36 | 58 |
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 13594048950 19923294409 | xingcanyaoye@sina.com | China | 1591 | 58 |
| Nantong Xiaochang Pharmaceutical Trading Co., Ltd. | 0513-82104991 18862997351 | sales11@btcpharm.com | China | 859 | 58 |
| Zhenjiang D&A Biological Technology Co., Ltd. | 18912101619 | wxf2005a@126.com | China | 95 | 58 |
| Shanghai Witofly Chemical Co. ,Ltd. | 02150630626 17717886015 | sales@witofly.com | China | 1864 | 55 |
| Shanghai Taijilin Industrial Co., Ltd. | 02150630626 17717886015 | kate@tajilin.com | China | 1341 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from Diglycolic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-17 | Diglycolic Anhydride
4480-83-5
|
$1.00 | 100g | 97.0%min | 20kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2026-03-20 | Diglycolic anhydride
4480-83-5
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-05-26 | Diglycolic anhydride
4480-83-5
|
$30.00 | 1kg | 0.99 | 20 tons | Hebei Fengjia New Material Co., Ltd |
-

- Diglycolic Anhydride
4480-83-5
- $1.00
- 97.0%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Diglycolic anhydride
4480-83-5
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Diglycolic anhydride
4480-83-5
- $30.00
- 0.99
- Hebei Fengjia New Material Co., Ltd





