SALOR-INT L224693-1EA
- CAS No.
- 313380-27-7
- Chemical Name:
- SALOR-INT L224693-1EA
- Synonyms
- 3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;FDI 6;FDI-6 >=98% (HPLC);FOXM1 Inhibitor III;FDI-6, 10 mM in DMSO;FDI 6 - NCGC 00099374;SALOR-INT L224693-1EA;inhibit,FDI-6,Inhibitor;FOXM1 Inhibitor III (FDI-6);3-AMINO-N-(4-FLUOROPHENYL)-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
- CBNumber:
- CB4384683
- Molecular Formula:
- C19H11F4N3OS2
- Molecular Weight:
- 437.43
- MDL Number:
- MFCD01416826
- MOL File:
- 313380-27-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| FDI-6 ≥98% (HPLC) | SML1392 | 5MG | $129 |
| FDI-6 ≥98% (HPLC) | SML1392 | 25MG | $509 |
| FOXM1 Inhibitor III, FDI-6 | 5.33259 | 10MG | $217 |
| FOXM1 Inhibitor III ≥98% | 36932 | 1mg | $32 |
| FOXM1 Inhibitor III ≥98% | 36932 | 5mg | $125 |
| Boiling point | 533.7±50.0 °C(Predicted) |
|---|---|
| Density | 1.562±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO:64.34(Max Conc. mg/mL);147.09(Max Conc. mM) |
| form | powder (flocculent) |
| pka | 10.24±0.70(Predicted) |
| color | white to beige |
| InChI | 1S/C19H11F4N3OS2/c20-9-3-5-10(6-4-9)25-17(27)16-15(24)14-11(19(21,22)23)8-12(26-18(14)29-16)13-2-1-7-28-13/h1-8H,24H2,(H,25,27) |
| InChIKey | ZATJMMZPGVDUOM-UHFFFAOYSA-N |
| SMILES | NC1=C(C(NC2=CC=C(F)C=C2)=O)SC3=C1C(C(F)(F)F)=CC(C4=CC=CS4)=N3 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338-P337+P313 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
SALOR-INT L224693-1EA price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1392 | FDI-6 ≥98% (HPLC) | 313380-27-7 | 5MG | $129 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1392 | FDI-6 ≥98% (HPLC) | 313380-27-7 | 25MG | $509 | 2026-04-30 | Buy |
| Sigma-Aldrich | 5.33259 | FOXM1 Inhibitor III, FDI-6 | 10MG | $217 | 2026-04-30 | Buy | |
| Cayman Chemical | 36932 | FOXM1 Inhibitor III ≥98% | 313380-27-7 | 1mg | $32 | 2026-04-30 | Buy |
| Cayman Chemical | 36932 | FOXM1 Inhibitor III ≥98% | 313380-27-7 | 5mg | $125 | 2026-04-30 | Buy |
SALOR-INT L224693-1EA Chemical Properties,Uses,Production
Uses
FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation.
Biochem/physiol Actions
Forkhead domain inhibitor-6 (FDI-6) is used to treat anaemia patients because of diminished red blood production. In Hep-2 cells, FDI-6 can stimulate cell death and also helps to prevent cell proliferation, invasion and migration.
References
[1] Gormally MV, et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165. DOI:10.1038/ncomms6165
SALOR-INT L224693-1EA Preparation Products And Raw materials
Raw materials
Preparation Products
SALOR-INT L224693-1EA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9636 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Apeloa Pharmaceutical Co., Ltd. | +86-0571-87635730 +8615858229168 | chem1022@hengdian-group.com | China | 1478 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Hangzhou IKSChem Technology Co., Limited | 13625816949 | zheng@ikschem.com | China | 979 | 58 |
| ShangHai IKSChem Technology Co.,LTD | +86-18337276608 | zheng@ikschem.com | China | 2402 | 58 |
| Zhengzhou convergence chemical co., LTD | 037155153829 18003835034 | 3897192574@qq.com | China | 9983 | 58 |
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