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4-Bromo-3,5-dimethylpyrazole

4-Bromo-3,5-dimethylpyrazole Structure
4-Bromo-3,5-dimethylpyrazole structure
CAS No.
3398-16-1
Chemical Name:
4-Bromo-3,5-dimethylpyrazole
Synonyms
4-BROMO-3,5-DIMETHYL-1H-PYRAZOLE;GF 12;AKOS B001459;AKOS PAO-1351;BUTTPARK 47\04-31;VITAS-BB TBB000654;IFLAB-BB F0900-0030;Bromo-3,5-dimethylpyrazole;4-BROMO-3,5-DIMETHYLPYRAZOLE;4-bromo-3,5-dimethyl-pyrazol
CBNumber:
CB4402295
Molecular Formula:
C5H7BrN2
Molecular Weight:
175.03
MDL Number:
MFCD00005242
MOL File:
3398-16-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:27:40
Request For Quotation

4-Bromo-3,5-dimethylpyrazole Properties

Melting point 123-125 °C(lit.)
Boiling point 269.1±35.0 °C(Predicted)
Density 1.595
refractive index 1.5500 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka 13.83±0.50(Predicted)
form powder to crystal
color White to Light yellow
BRN 108534
InChI InChI=1S/C5H7BrN2/c1-3-5(6)4(2)8-7-3/h1-2H3,(H,7,8)
InChIKey RISOHYOEPYWKOB-UHFFFAOYSA-N
SMILES N1C(C)=C(Br)C(C)=N1
CAS DataBase Reference 3398-16-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 3AT7M73HWM

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
RTECS  UQ6210000
HazardClass  IRRITANT
HS Code  29331990
Toxicity LD50 intraperitoneal in mouse: 580mg/kg
NFPA 704
1
2 0

4-Bromo-3,5-dimethylpyrazole price More Price(88)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B3306 4-Bromo-3,5-dimethylpyrazole >98.0%(GC)(T) 3398-16-1 5g $28 2026-04-30 Buy
TCI Chemical B3306 4-Bromo-3,5-dimethylpyrazole >98.0%(GC)(T) 3398-16-1 25g $77 2026-04-30 Buy
Usbiological 263946 4-Bromo-3,5-dimethylpyrazole Asreported 3398-16-1 10g $305 2026-06-03 Buy
Usbiological 263946 4-Bromo-3,5-dimethylpyrazole Asreported 3398-16-1 25g $403 2026-06-03 Buy
Usbiological 263946 4-Bromo-3,5-dimethylpyrazole Asreported 3398-16-1 50g $531 2026-06-03 Buy
Product number Packaging Price Buy
B3306 5g $28 Buy
B3306 25g $77 Buy
263946 10g $305 Buy
263946 25g $403 Buy
263946 50g $531 Buy

4-Bromo-3,5-dimethylpyrazole Chemical Properties, Uses, Production

Chemical Properties

white crystalline powder

Uses

4-Bromo-3,5-dimethylpyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

3,5-Dimethylpyrazole

67-51-6

4-Bromo-3,5-dimethylpyrazole

3398-16-1

The general procedure for the synthesis of 3,5-dimethyl-4-bromopyrazole from 3,5-dimethylpyrazole is as follows: 1. In a 16 mL vial, 1-benzyl-3,5-dimethyl-1H-pyrazole (196 mg, 1.05 mmol), a magnetic stir bar, 0.7 mL of water, and 0.3 mL of ethyl acetate were added. 2. NaCl (123 mg, 2 mmol) was added and the vial was placed in a room temperature water bath to control the exothermic nature of the reaction. 3. Oxone (322 mg, 0.52 mmol or 1.05 mmol KHSO5) was added and the vial was capped. 4. React under continuous vigorous stirring until thin layer chromatography (TLC) analysis (1 hr) showed complete consumption of the raw material. 5. Reduce the remaining oxidizing agent using solid sodium bisulfite until the starch iodide paper tests negative. 6. Water (5 mL) was added and the reaction mixture was extracted with a 1:1 hexane/ether solvent mixture (3 x 5 mL). 7. The organic phases were combined, dried over anhydrous magnesium sulfate (MgSO4) and concentrated to give the crude product. 8. The crude product was purified by fast chromatography (14 x 1 cm, eluent 9:1 hexane/ethyl acetate) to afford pure 1-benzyl-4-chloro-3,5-dimethyl-1H-pyrazole as a light yellow oil (215 mg, 93% yield).

References

[1] Tetrahedron Letters, 2005, vol. 46, # 40, p. 6833 - 6837
[2] Chemical & Pharmaceutical Bulletin, 1988, vol. 36, # 10, p. 3838 - 3848
[3] Tetrahedron Letters, 2017, vol. 58, # 43, p. 4111 - 4114
[4] Canadian Journal of Chemistry, 1992, vol. 70, # 4, p. 1121 - 1128
[5] Journal of the Chemical Society, 1923, vol. 123, p. 1315

4-Bromo-3,5-dimethylpyrazole Preparation Products And Raw materials

Raw materials

3,5-Dimethylpyrazole Potassium peroxymonosulfate Sodium bromide

Preparation Products

1,3,5-Trimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 4-Bromo-1,3,5-trimethyl-1H-pyrazole 4-Bromo-3,5-dimethyl-1-(4-nitro-phenyl)-1H-pyrazole

4-Bromo-3,5-dimethylpyrazole Suppliers

Global Suppliers ( 246)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11592 64
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 64
Jia Xing Isenchem Co.,Ltd 66

View Latest Price from 4-Bromo-3,5-dimethylpyrazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-3,5-dimethylpyrazole pictures 2026-07-21 4-Bromo-3,5-dimethylpyrazole
3398-16-1
 1kg 98% 20TON Hubei Lidu New Material Technology Co., Ltd
4-Bromo-3,5-dimethylpyrazole pictures 2026-06-30 4-Bromo-3,5-dimethylpyrazole
3398-16-1
 1KG 98 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Bromo-3,5-dimethylpyrazole pictures 2026-03-20 4-Bromo-3,5-dimethylpyrazole
3398-16-1
 $8.00-10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd

4-Bromo-3,5-dimethylpyrazole Spectrum

4-Bromo-3,5-dimethylpyrazole(3398-16-1)1HNMR4-Bromo-3,5-dimethylpyrazole(3398-16-1)FT-IR

3398-16-1 (4-Bromo-3,5-dimethylpyrazole) Related Search:

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Ethane Zolpidem Bromine

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4-BROMO-3,5-DIMETHYLPYRAZOLE AKOS B001459 AKOS PAO-1351 VITAS-BB TBB000654 IFLAB-BB F0900-0030 BUTTPARK 47\04-31 4-bromo-3,5-dimethyl-pyrazol 3,5-Dimethyl-4-bromoisoxazole 4-Bromo-3,5-dimethylpyrazole,99% 3.5-Dimethyl-4-bromo pyrazole 3,5- two Methylpyrazole-4-broMide 3,5- two-4- MethylbroMidepyrazole 3, 5 - diMethyl - 4 - broMine pyrazole 4-Bromo-3,5-dimethyl-1H-pyrazole,99% GF 12 Pyrazole, 4-bromo-3,5-dimethyl- 4-Bromo-3,5-dimethylpyrazole > 1H-Pyrazole, 4-bromo-3,5-dimethyl- 4-BROMO-3,5-DIMETHYLPYRAZOLE 3398-16-1 Bromo-3,5-dimethylpyrazole 4-BROMO-3,5-DIMETHYL-1H-PYRAZOLE 3398-16-1 C5H7BrN2 Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Pyrazoles Building Blocks C3 to C5 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Halides Pyrazoles & Triazoles Pyrazoles & Triazoles Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyrazoles PyrazolesHeterocyclic Building Blocks bc0001