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2-Amino-4-(4-chlorophenyl)thiazole

CAS No.
2103-99-3
Chemical Name:
2-Amino-4-(4-chlorophenyl)thiazole
Synonyms
4-(4-CHLOROPHENYL)THIAZOL-2-AMINE;f1654;AURORA 13234;AKOS B000490;TOSLAB 14871;AKOS BBS-00000674;BUTTPARK 18\03-88;IFLAB-BB F1912-0041;TIMTEC-BB SBB000503;OTAVA-BB BB7010240509
CBNumber:
CB4404608
Molecular Formula:
C9H7ClN2S
Molecular Weight:
210.68
MDL Number:
MFCD00047058
MOL File:
2103-99-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:49

2-Amino-4-(4-chlorophenyl)thiazole Properties

Melting point 169-171 °C(lit.)
Boiling point 389.8±17.0 °C(Predicted)
Density 1.389±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 3.95±0.10(Predicted)
form Powder
color White to off-white
λmax 232nm(phosphate buffer sol.)(lit.)
BRN 153889
InChI 1S/C9H7ClN2S/c10-7-3-1-6(2-4-7)8-5-13-9(11)12-8/h1-5H,(H2,11,12)
InChIKey DWGWNNCHJPKZNC-UHFFFAOYSA-N
SMILES Nc1nc(cs1)-c2ccc(Cl)cc2
LogP 3.411 (est)
CAS DataBase Reference 2103-99-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII WFJ6DX9BPJ
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38
Safety Statements  26-36-36/37/39
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  XJ1026732
HazardClass  IRRITANT
PackingGroup  III
HS Code  29341000
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-Amino-4-(4-chlorophenyl)thiazole price More Price(75)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 339369 2-Amino-4-(4-chlorophenyl)thiazole 98% 2103-99-3 1g $25.5 2023-01-07 Buy
TCI Chemical A2841 2-Amino-4-(4-chlorophenyl)thiazole >98.0%(GC)(T) 2103-99-3 1g $61 2026-04-30 Buy
TCI Chemical A2841 2-Amino-4-(4-chlorophenyl)thiazole >98.0%(GC)(T) 2103-99-3 5g $215 2026-04-30 Buy
Biosynth FA36275 2-Amino-4-(4-chlorophenyl)thiazole 2103-99-3 1g $250 2026-06-04 Buy
Biosynth FA36275 2-Amino-4-(4-chlorophenyl)thiazole 2103-99-3 5g $250 2026-06-04 Buy
Product number Packaging Price Buy
339369 1g $25.5 Buy
A2841 1g $61 Buy
A2841 5g $215 Buy
FA36275 1g $250 Buy
FA36275 5g $250 Buy

2-Amino-4-(4-chlorophenyl)thiazole Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powde

Uses

2-Amino-4-(4-chlorophenyl)thiazole was used in the preparation of 2-chloroacetamido-4-(4-chlorophenyl)thiazole.

Synthesis

Carbamimidothioic acid

17356-08-0

4-Chloro-2'-bromoacetophenone

536-38-9

2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE

2103-99-3

GENERAL METHOD: A mixture of thiourea (1.2 mmol) and α-bromo-4-chloroacetophenone (1 mmol) in ethanol (2 mL) was stirred and reacted at 70 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature, poured into ice water, filtered to collect the precipitate precipitated, and dried to obtain the target product 2-amino-4-(4-chlorophenyl)thiazole. The product yields and physical properties were as follows: [6a (99% yield), white solid, melting point 150-152 °C (literature value 26: 149-150 °C); 6b (100% yield), white solid, melting point 162-165 °C (literature value 26: 163-164 °C); 6c (0.236 g, 93% yield), white solid, melting point 179-181 °C (literature value 26: 180-181 °C); 6d (98% yield), white solid, melting point 203.6-204.2 °C (literature value 28/22: 204.0-204.5 °C); 6e (94% yield), bright yellow solid, melting point 287-288 °C (literature values 26,27: 285-286 °C); 6f (100% yield), white solid, melting point 172-174°C (literature values 29-31: 172°C).

References

[1] Arkivoc, 2018, vol. 2018, # 7, p. 110 - 118
[2] Chinese Chemical Letters, 2014, vol. 25, # 1, p. 172 - 175
[3] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8099 - 8109
[4] Molecules, 2017, vol. 22, # 5,
[5] Synthetic Communications, 2009, vol. 39, # 16, p. 2895 - 2906

Global Suppliers ( 164)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57

View Latest Price from 2-Amino-4-(4-chlorophenyl)thiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Histone acetyltransferase p300 Inhibitor 4c pictures 2026-08-08 Histone acetyltransferase p300 Inhibitor 4c
2103-99-3
99.86% 10g TargetMol Chemicals Inc.
2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE pictures 2020-01-13 2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE
2103-99-3
$9.80 1g ≥99% 100kg Career Henan Chemical Co
2-AMINO 4(P-CHLORO)PHENYL THIAZOLE AKOS B000490 AKOS BBS-00000674 4-(4-CHLORO-PHENYL)-THIAZOL-2-YLAMINE 4-(4-CHLOROPHENYL)-1,3-THIAZOL-2-AMINE AURORA 13234 BUTTPARK 18\03-88 IFLAB-BB F1912-0041 4-(4-chlorophenyl)-2-thiazolamin 4-(4-chlorophenyl)-2-thiazolamine f1654 p-chlorophenyl-4amino-2thiazole TOSLAB 14871 TIMTEC-BB SBB000503 OTAVA-BB BB7010240509 4-(4-chlorophenyl)-1,3-thiazol-2-ylamine 4-(4-chlorophenyl)-1,3-thiazol-2-amine(SALTDATA: FREE) 2-Thiazolamine, 4-(4-chlorophenyl)- p-Chloro phenyl-4 amino-2 thiazole [French] Thiazol-2-amine, 4-(4-chlorophenyl)- Thiazole, 2-amino-4-(p-chlorophenyl)- 2-Amino-4-(4-chlorophenyl)thiazole 98% JR-8887, 2-Amino-4-(4-chlorophenyl)thiazole, 97% Histone acetyltransferase p300 Inhibitor 4c 4-(4-CHLOROPHENYL)THIAZOL-2-AMINE 2-Amino-4-(4-chlorophenyl)thiazole 2103-99-3 C9H7ClN2S C9H7ClN2SBrH Halogenated Heterocycles Heterocyclic Building Blocks Thiazoles Building Blocks Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Thiazoles ThiazolesHeterocyclic Building Blocks Building Blocks C8 to C9 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks