2-Amino-4-(4-chlorophenyl)thiazole
- CAS No.
- 2103-99-3
- Chemical Name:
- 2-Amino-4-(4-chlorophenyl)thiazole
- Synonyms
- 4-(4-CHLOROPHENYL)THIAZOL-2-AMINE;f1654;AURORA 13234;AKOS B000490;TOSLAB 14871;AKOS BBS-00000674;BUTTPARK 18\03-88;IFLAB-BB F1912-0041;TIMTEC-BB SBB000503;OTAVA-BB BB7010240509
- CBNumber:
- CB4404608
- Molecular Formula:
- C9H7ClN2S
- Molecular Weight:
- 210.68
- MDL Number:
- MFCD00047058
- MOL File:
- 2103-99-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 169-171 °C(lit.) |
|---|---|
| Boiling point | 389.8±17.0 °C(Predicted) |
| Density | 1.389±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 3.95±0.10(Predicted) |
| form | Powder |
| color | White to off-white |
| λmax | 232nm(phosphate buffer sol.)(lit.) |
| BRN | 153889 |
| InChI | 1S/C9H7ClN2S/c10-7-3-1-6(2-4-7)8-5-13-9(11)12-8/h1-5H,(H2,11,12) |
| InChIKey | DWGWNNCHJPKZNC-UHFFFAOYSA-N |
| SMILES | Nc1nc(cs1)-c2ccc(Cl)cc2 |
| LogP | 3.411 (est) |
| CAS DataBase Reference | 2103-99-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | WFJ6DX9BPJ |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-36/37/39 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XJ1026732 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29341000 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Amino-4-(4-chlorophenyl)thiazole price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 339369 | 2-Amino-4-(4-chlorophenyl)thiazole 98% | 2103-99-3 | 1g | $25.5 | 2023-01-07 | Buy |
| TCI Chemical | A2841 | 2-Amino-4-(4-chlorophenyl)thiazole >98.0%(GC)(T) | 2103-99-3 | 1g | $61 | 2026-04-30 | Buy |
| TCI Chemical | A2841 | 2-Amino-4-(4-chlorophenyl)thiazole >98.0%(GC)(T) | 2103-99-3 | 5g | $215 | 2026-04-30 | Buy |
| Biosynth | FA36275 | 2-Amino-4-(4-chlorophenyl)thiazole | 2103-99-3 | 1g | $250 | 2026-06-04 | Buy |
| Biosynth | FA36275 | 2-Amino-4-(4-chlorophenyl)thiazole | 2103-99-3 | 5g | $250 | 2026-06-04 | Buy |
2-Amino-4-(4-chlorophenyl)thiazole Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal powde
Uses
2-Amino-4-(4-chlorophenyl)thiazole was used in the preparation of 2-chloroacetamido-4-(4-chlorophenyl)thiazole.
Synthesis
17356-08-0
536-38-9
2103-99-3
GENERAL METHOD: A mixture of thiourea (1.2 mmol) and α-bromo-4-chloroacetophenone (1 mmol) in ethanol (2 mL) was stirred and reacted at 70 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature, poured into ice water, filtered to collect the precipitate precipitated, and dried to obtain the target product 2-amino-4-(4-chlorophenyl)thiazole. The product yields and physical properties were as follows: [6a (99% yield), white solid, melting point 150-152 °C (literature value 26: 149-150 °C); 6b (100% yield), white solid, melting point 162-165 °C (literature value 26: 163-164 °C); 6c (0.236 g, 93% yield), white solid, melting point 179-181 °C (literature value 26: 180-181 °C); 6d (98% yield), white solid, melting point 203.6-204.2 °C (literature value 28/22: 204.0-204.5 °C); 6e (94% yield), bright yellow solid, melting point 287-288 °C (literature values 26,27: 285-286 °C); 6f (100% yield), white solid, melting point 172-174°C (literature values 29-31: 172°C).
References
[1] Arkivoc, 2018, vol. 2018, # 7, p. 110 - 118
[2] Chinese Chemical Letters, 2014, vol. 25, # 1, p. 172 - 175
[3] Research on Chemical Intermediates, 2015, vol. 41, # 11, p. 8099 - 8109
[4] Molecules, 2017, vol. 22, # 5,
[5] Synthetic Communications, 2009, vol. 39, # 16, p. 2895 - 2906
2-Amino-4-(4-chlorophenyl)thiazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Latest Price from 2-Amino-4-(4-chlorophenyl)thiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-08-08 | Histone acetyltransferase p300 Inhibitor 4c
2103-99-3
|
99.86% | 10g | TargetMol Chemicals Inc. | |||
![]() |
2020-01-13 | 2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE
2103-99-3
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-

- Histone acetyltransferase p300 Inhibitor 4c
2103-99-3
- $0.00
- 99.86%
- TargetMol Chemicals Inc.
-

- 2-AMINO-4-(4-CHLOROPHENYL)THIAZOLE
2103-99-3
- $9.80
- ≥99%
- Career Henan Chemical Co
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