9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt
- CAS No.
- 89847-02-9
- Chemical Name:
- 9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt
- Synonyms
- (5R)-Dinoprost tromethamine;9BETA-PGF2ALPHA (TROMETHAMINE SALT);Prostaglandin F2β (tromethamine salt);PROSTAGLANDIN F2BETA TROMETHAMINE SALT;9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt;2-amino-2-(hydroxymethyl)propane-1,3-diol (Z)-7-((1R,2R,3R,5R)-3,5-dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoate
- CBNumber:
- CB4408929
- Molecular Formula:
- C24H45NO8
- Molecular Weight:
- 475.62
- MDL Number:
- MFCD00135236
- MOL File:
- 89847-02-9.mol
- MSDS File:
- SDS
9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt Properties
| solubility | Acetone: >5 mg/ml (from PGF2a THAM); Acetonitrile: >5 mg/ml (from PGF2a THAM); DMSO: >50 mg/ml (from PGF2a THAM); Ethanol: >50 mg/ml (from PGF2a THAM); Methanol: >100 mg/ml (from PGF2a THAM); PBS pH 7.2: >25 mg/ml (from PGF2a THAM) |
|---|---|
| form | A crystalline solid |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H360 | |||||||||
| Precautionary statements | P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501 | |||||||||
| NFPA 704 |
|
9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16420 | Prostaglandin F2β (tromethamine salt) ≥99% | 89847-02-9 | 1mg | $93 | 2026-04-30 | Buy |
| Cayman Chemical | 16420 | Prostaglandin F2β (tromethamine salt) ≥99% | 89847-02-9 | 5mg | $406 | 2026-04-30 | Buy |
| Cayman Chemical | 16420 | Prostaglandin F2β (tromethamine salt) ≥99% | 89847-02-9 | 10mg | $717 | 2026-04-30 | Buy |
| ChemScene | CS-0133857 | (5R)-Dinoprost tromethamine | 89847-02-9 | 1mg | $200 | 2026-06-04 | Buy |
| ChemScene | CS-0133857 | (5R)-Dinoprost tromethamine | 89847-02-9 | 5mg | $880 | 2026-06-04 | Buy |
9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt Chemical Properties,Uses,Production
Description
Prostaglandin F2β (PGF2β) (tromethamine salt) is a derivative of PGF2β with increased water solubility. PGF2β is the 9β-hydroxy stereoisomer of PGF2α . It is much less active than PGF2α in antifertility and bronchoconstrictor activities. PGF2β exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2α.
Uses
(5R)-Dinoprost tromethamine (Prostaglandin F2β tromethamine) is a metabolite produced by the metabolism of arachidonic acid cyclooxygenase. (5R)-Dinoprost tromethamine induces dose-dependent release of hexosaccharide containing mucin[1][2].
References
[1] Lamont JT, et, al. Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb;84(2):306-13. PMID:6184259
[2] Jang Y, et, al. Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception. J Neuroinflammation. 2020 Jan 22;17(1):30. DOI:10.1186/s12974-020-1703-1
9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt Preparation Products And Raw materials
Raw materials
Preparation Products
9beta,11alpha,15S-trihydroxy-prosta-5z,13e-dien-1-oic acid, Tris (hydroxymethyl)aminomethane salt Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| TargetMol | 58 |
