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N-Desmethyl zopiclone

N-Desmethyl zopiclone Structure
N-Desmethyl zopiclone structure
CAS No.
59878-63-6
Chemical Name:
N-Desmethyl zopiclone
Synonyms
RP32273;Norzopiclone;Desmethylzopiclone;Zopiclone Impurity E;N-Desmethyl zopiclone;N-Desmethylzopiclone solution;N-Desmethyl Zopiclone Impurity;N-Desmethyl Zopiclone Hydrochloride;N-Desmethyl zopiclone Solution, 100ppm;6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxyl
CBNumber:
CB4409320
Molecular Formula:
C16H15ClN6O3
Molecular Weight:
374.78
MDL Number:
MFCD08063745
MOL File:
59878-63-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:49
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N-Desmethyl zopiclone Properties

Melting point 226-2280C
Boiling point 599.0±50.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
Flash point 2°C
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka 8.26±0.10(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02, GHS07
Signal word  Danger
Hazard statements  H225-H302+H332-H319
Precautionary statements  P210-P305+P351+P338
RIDADR  UN 1648 3 / PGII
WGK Germany  2

N-Desmethyl zopiclone price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D-111 N-Desmethylzopiclone solution 100?μg/mL in acetonitrile, certified reference material, Cerilliant? 59878-63-6 1mL $133 2026-04-30 Buy
Biosynth FD21348 N-Desmethyl zopiclone hydrochloride 59878-63-6 1mg $250 2026-06-04 Buy
Biosynth FD21348 N-Desmethyl zopiclone hydrochloride 59878-63-6 5mg $923.95 2026-06-04 Buy
Biosynth FD21348 N-Desmethyl zopiclone hydrochloride 59878-63-6 10mg $1478.2 2026-06-04 Buy
ChemScene CS-7301 Norzopiclone 59878-63-6 1mg $498 2026-06-04 Buy
Product number Packaging Price Buy
D-111 1mL $133 Buy
FD21348 1mg $250 Buy
FD21348 5mg $923.95 Buy
FD21348 10mg $1478.2 Buy
CS-7301 1mg $498 Buy

N-Desmethyl zopiclone Chemical Properties, Uses, Production

Chemical Properties

White to Off-White Solid

Uses

A metabolite of Zopiclone (Z700500).

Uses

N-Desmethyl Zopiclone is a metabolite of Zopiclone (Z700500), N-Desmethyl Zopiclone is an intermediate in the synthesis of N-Desmethyl Zopiclone Hydrochloride (D296770).

in vivo

A demethylation metabolic pathway produces Norzopiclone (N-desmethylzopiclone), a metabolite which reportedly accounts for 15% of an oral dose of racemic Zopiclone, and which is also reportedly inactive[2]. N-oxide-Zopiclone has a similar t1/2 compared to parent Zopiclone, while the t1/2 of Norzopiclone (N-desmethyl-Zopiclone) ranges from 7 to 11 h[3].

N-Desmethyl zopiclone Preparation Products And Raw materials

Raw materials

Preparation Products

N-Desmethyl zopiclone Suppliers

Global Suppliers ( 37)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Artis Chemistry (Shanghai) Co. Ltd. 86-21-60936353 China 335 58
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1949 55
Shandong Boluoda Biological Technology Co., Ltd. 0531-68651502 2310993908@qq.com China 3228 58
Nanjing ERan Biological Pharmaceutical Co., Ltd. 13770809694 googlexu_0114@sina.com China 992 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Nanjing Nohon Biological Technology Co., Ltd. 025-85767923 18512596075; sales@nuoxibio.com China 975 55
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9609 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Artis Chemistry (Shanghai) Co. Ltd. 58
Clearsynth Labs Limited 58
Cato Research Chemicals Inc. 55
Shandong Boluoda Biological Technology Co., Ltd. 58
Nanjing ERan Biological Pharmaceutical Co., Ltd. 58
Amadis Chemical Company Limited 58
Nanjing Nohon Biological Technology Co., Ltd. 55
Shenzhen SUNGENING Bio-Medical Co., Ltd. 60

59878-63-6 (N-Desmethyl zopiclone) Related Search:

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1of2

N-Desmethyl Zopiclone Hydrochloride Piperazine -1-carboxylic Acid 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester Hydrochloride 6-(5-CHLOROPYRIDIN-2-YL)-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRAZIN-5-YL PIPERAZINE-1-CARBOXYLATE Desmethylzopiclone 1-Piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b] pyrazin-5-yl ester 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxyl Norzopiclone N-Desmethyl zopiclone Solution, 100ppm N-Desmethyl Zopiclone Impurity N-Desmethylzopiclone solution N-Desmethyl ZopicloneQ: What is N-Desmethyl Zopiclone Q: What is the CAS Number of N-Desmethyl Zopiclone Q: What is the storage condition of N-Desmethyl Zopiclone Q: What are the applications of N-Desmethyl Zopiclone RP32273 Zopiclone Impurity E N-Desmethyl zopiclone 59878-63-6 C16H16Cl2N6O3 Isotopically Labeled Pharmaceutical Reference Standard Heterocycles GABA/Glycine receptor Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals