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(R)-(+)-1-(4-PYRIDYL)ETHANOL

(R)-(+)-1-(4-PYRIDYL)ETHANOL structure

CAS No.: 27854-88-2

Chemical Name:: (R)-(+)-1-(4-PYRIDYL)ETHANOL

Synonyms: (r)-(+)-α-methyl-4-pyridinemethanol;(1R)-1-(4-Pyridyl)ethanol;(R)-1-(pyridin-4-yl)ethanol;(R)-(+)-1-(4-PYRIDYL)ETHANOL;4-[(R)-1-Hydroxyethyl]pyridine;(R)-1-(pyridin-4-yl)ethan-1-ol;(1R)-1-(pyridin-4-yl)ethan-1-ol;(R)-4-(1-HYDROXYETHYL) PYRIDINE;(R)-α-Methylpyridine-4-methanol;(aR)-a-Methyl-4-PyridineMethanol

CBNumber:: CB4444367

Molecular Formula:: C7H9NO

Molecular Weight:: 123.15

MDL Number:: MFCD00077865

MOL File:: 27854-88-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 03:20:42

Product description	Number	Pack Size	Price
(R)-(+)-α-Methyl-4-pyridinemethanol 99%	448532	1g	$160
(R)-4-(1-Hydroxyethyl)pyridine	H1733	1G	$78
(R)-4-(1-Hydroxyethyl)pyridine	H1733	5G	$273
(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98% min.98%	07-1160	50mg	$70
(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98% min.98%	07-1160	100mg	$111
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(R)-(+)-1-(4-PYRIDYL)ETHANOL Properties

Melting point	67-69 °C(lit.)
Boiling point	239.7±15.0 °C(Predicted)
Density	1.082±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	soluble in Methanol
form	Crystalline Powder or Needles
pka	13.52±0.20(Predicted)
color	White
optical activity	[α]20/D +55°, c = 1 in chloroform
BRN	4306037
InChI	1S/C7H9NO/c1-6(9)7-2-4-8-5-3-7/h2-6,9H,1H3/t6-/m1/s1
InChIKey	HVOAMIOKNARIMR-ZCFIWIBFSA-N
SMILES	C[C@@H](O)c1ccncc1
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

3-10

HS Code

29333999

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

(R)-(+)-1-(4-PYRIDYL)ETHANOL price More Price(66)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	448532	(R)-(+)-α-Methyl-4-pyridinemethanol 99%	27854-88-2	1g	$160	2023-01-07	Buy
TCI Chemical	H1733	(R)-4-(1-Hydroxyethyl)pyridine	27854-88-2	1G	$78	2026-04-30	Buy
TCI Chemical	H1733	(R)-4-(1-Hydroxyethyl)pyridine	27854-88-2	5G	$273	2026-04-30	Buy
Strem Chemicals	07-1160	(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98% min.98%	27854-88-2	50mg	$70	2026-04-30	Buy
Strem Chemicals	07-1160	(R)-(+)-α-Methyl-4-pyridinemethanol, min. 98% min.98%	27854-88-2	100mg	$111	2026-04-30	Buy

Product number	Packaging	Price	Buy
448532	1g	$160	Buy
H1733	1G	$78	Buy
H1733	5G	$273	Buy
07-1160	50mg	$70	Buy
07-1160	100mg	$111	Buy

(R)-(+)-1-(4-PYRIDYL)ETHANOL Chemical Properties,Uses,Production

Reaction

Used for the synthesis of chiral 1-(4-pyridinyl)ethylamines
Precursor for intermediates of highly stable chiral (A)6-B Supramolecular Copolymers

Chemical Properties

White needles

Uses

(1R)-1-(4-Pyridyl)ethanol is a building block reagent used in the synthesis of potent GPR119 receptor agonists used in the treatment of diabetes.

Synthesis

1122-54-9

27854-88-2

GENERAL PROCEDURE: BH3-SMe2 (2.0 M toluene solution, 250 μL, 500 μmol) was added to a pre-prepared toluene (1 mL) solution of B-alkoxyoxazaborolidine 8 (7.43 mg, 25.0 μmol) (refer to Procedure 1.2.6 for preparation). The reaction mixture was kept at 50°C for 15 min and then cooled to 20°C. Subsequently, a solution of acetophenone (1a, 60.1 mg, 58.3 μL, 500 μmol) in toluene (1 mL) was slowly added dropwise over 60 min using a syringe pump. After the dropwise addition, the reaction was continued with stirring for 10 min, and then the reaction was quenched by the addition of H2SO4 (1.1 M, 500 μL). The mixture was stirred for another 15 min and then directly separated by column chromatography (silica gel, pentane/Et2O 2:1) to afford the target product (R)-1-(pyridin-4-yl)ethanol ((R)-2a, 58.3 mg, 477 μmol, 95% yield, 97% ee) as a colorless oil.

Purification Methods

Purify it by recrystallisation from pet ether. The m recorded after sublimation was 59.9-60.2o, and 55o after crystallisation from *C6H6/pet ether or pet ether/*C6H6. The (-)-di-O-benzoyl tartrate salt has m 146-148o (from EtOH). [UV, ORD: Harelli & Samori J Chem Soc Perkin Trans 2 1462 1974.] The racemate recrystallises from Et2O with m 74-76o,b 90-94o/1mm. The picrate has m 125-126o (from *C6H6). [Ferles & Attia Collect Czech Chem Commun 38 611 1973, UV, NMR: Nielson et al. J Org Chem 29 2898 1964, Beilstein 21 III/IV 522, 21/2 V 217.]

References

[1] Organic Letters, 2017, vol. 19, # 3, p. 690 - 693
[2] Advanced Synthesis and Catalysis, 2014, vol. 356, # 10, p. 2293 - 2302
[3] Tetrahedron Letters, 2016, vol. 57, # 23, p. 2492 - 2495
[4] Synlett, 1997, vol. 1997, # 3, p. 273 - 274
[5] Synthesis, 2009, # 14, p. 2413 - 2417

(R)-(+)-1-(4-PYRIDYL)ETHANOL Preparation Products And Raw materials

Raw materials

4-Acetylpyridine 1-PYRIDIN-4-YL-ETHANOL Vinyl acetate Toluene Borane-methyl sulfide complex

Preparation Products

(R)-(+)-1-(4-PYRIDYL)ETHANOL Suppliers

Global( 119)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16512	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5973	58
Dideu Industries Group Limited	+86-86-15536356810 +8617392712697	1022@dideu.com	China	28755	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
ATK CHEMICAL COMPANY LIMITED	60
Zhejiang ZETian Fine Chemicals Co. LTD	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Win-Win chemical CO., Limited	58
ANHUI WITOP BIOTECH CO., LTD	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Dideu Industries Group Limited	58

View Lastest Price from (R)-(+)-1-(4-PYRIDYL)ETHANOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-02	(R)-(+)-1-(4-Pyridyl)ethanol 27854-88-2	$1.10-9.90	1kg	99%min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-11-18	(R)-(+)-1-(4-PYRIDYL)ETHANOL 27854-88-2	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2025-04-04	(R)-(+)-1-(4-PYRIDYL)ETHANOL 27854-88-2		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

(R)-(+)-1-(4-Pyridyl)ethanol
27854-88-2
$1.10-9.90
99%min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

(R)-(+)-1-(4-PYRIDYL)ETHANOL
27854-88-2
$1.10
99.00%
Dideu Industries Group Limited

(R)-(+)-1-(4-PYRIDYL)ETHANOL
27854-88-2
98%
Henan Aochuang Chemical Co.,Ltd.

(R)-(+)-1-(4-PYRIDYL)ETHANOL Spectrum

(R)-(+)-1-(4-PYRIDYL)ETHANOL(27854-88-2)¹HNMR

27854-88-2((R)-(+)-1-(4-PYRIDYL)ETHANOL)Related Search:

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1of4

4-[(R)-1-Hydroxyethyl]pyridine (R)-4-(1-Hydroxyethyl)pyridine,99+%,(99+% ee) (R)-4-(1-Hydroxyethyl)pyridine(R)-(+)-1-(4-Pyridyl)ethanol (R)-1-(pyridin-4-yl)ethanol (1R)-1-(pyridin-4-yl)ethan-1-ol 4-PyridineMethanol, α-Methyl-, (R)- (aR)-a-Methyl-4-PyridineMethanol (R)-(+)-alpha-Methyl-4-pyridinemethanol 99% (R)-1-(pyridin-4-yl)ethan-1-ol (αR)-α-Methyl-4-pyridinemethanol,99%e.e. (R)-(+)-1-(4-PYRIDYL)ETHANOL (R)-(+)-ALPHA-METHYL-4-PYRIDINEMETHANOL (R)-4-(1-HYDROXYETHYL) PYRIDINE (R)-(+)-ALPHA-METHYL-4-PYRIDINEMETHANOL, 99% (98% EE/GLC) (R)-4-(1-Hydroxyethyl)pyridine, (99+% ee), 99+% (R)-4-(1-Hydroxyethyl)pyridine, (99+% ee) (1R)-1-(4-Pyridyl)ethanol (R)-α-Methylpyridine-4-methanol (αR)-α-Methylpyridine-4-methanol (R)-(+)-Α-METHYL-4-PYRIDINEMETHANOL,MIN.98% (R)-(+)-α-Methyl-4-pyridinemethanol, min. 98% -Methyl-4-pyridinemethanol, min. 98% (R)-1-(pyridin-4-yl)ethan-1-ol27854-88-2 4-Pyridinemethanol, α-methyl-, (αR)- (R)-(+)-1-(4-PYRIDYL)ETHANOL ISO 9001：2015 REACH 2-Thiazolamine,5-bromo-,hydrobromide(1:3) 1-Naphthalenecarbonitrile,9-methyl- 2-Amino-4-(4-fluorbenzylamino)-5-ethoxycarbonylaminobenzene (αR)-α-methyl-4-Pyridinemethanol (R)-(+)-α-Methyl-4-pyridinemethanol (R)-(+)-α-Methyl-4-pyridinemethanol, CAS 27854-88-2 (r)-(+)-α-methyl-4-pyridinemethanol 27854-88-2 Chiral Resolution Reagents Chiral Resolving Reagents Asymmetric Synthesis Alcohols, Hydroxy Esters and Derivatives Chiral Compounds