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2H-1,2,3 Triazole-2-acetic acid

CAS No.
4320-91-6
Chemical Name:
2H-1,2,3 Triazole-2-acetic acid
Synonyms
AP8Impurity;2H-1,2,3 Triazole-2-acetic acid;2-(2H-1,2,3-triazol-2-yl)acetic acid
CBNumber:
CB4458252
Molecular Formula:
C4H5N3O2
Molecular Weight:
127.1
MDL Number:
MFCD03840810
MOL File:
4320-91-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:50

2H-1,2,3 Triazole-2-acetic acid Properties

Boiling point 344.0±44.0 °C(Predicted)
Density 1.53±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 2+-.0.10(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2H-1,2,3 Triazole-2-acetic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS36256 2H-1,2,3-Triazole-2-acetic acid 97% 4320-91-6 1g $118 2026-06-04 Buy
Activate Scientific AS36256 2H-1,2,3-Triazole-2-acetic acid 97% 4320-91-6 5g $398 2026-06-04 Buy
AK Scientific W6268 2H-1,2,3-Triazole-2-acetic acid 95% 4320-91-6 1g $75 2026-06-04 Buy
AK Scientific W6268 2H-1,2,3-Triazole-2-acetic acid 95% 4320-91-6 5g $261 2026-06-04 Buy
Matrix Scientific 076486 2H-1,2,3-Triazole-2-acetic acid 4320-91-6 250.00mg $36 2026-05-18 Buy
Product number Packaging Price Buy
AS36256 1g $118 Buy
AS36256 5g $398 Buy
W6268 1g $75 Buy
W6268 5g $261 Buy
076486 250.00mg $36 Buy

2H-1,2,3 Triazole-2-acetic acid Chemical Properties, Uses, Production

Synthesis

2H-1,2,3 TRIAZOLE-2-ACETIC ACID ETHYL ESTER

4320-90-5

2H-1,2,3 TRIAZOLE-2-ACETIC ACID

4320-91-6

The general procedure for the synthesis of 2H-2-acetic acid-1,2,3-triazole-1,2,3-triazole from ethyl 2-(2H-1,2,3-triazol-2-yl)acetate was as follows: 1. Preparation of 2H-1,2,3-triazol-2-ylacetic acid: a solution of lithium hydroxide monohydrate (2.5 g, 60 mmol) in water (15 mL) was added to a solution of ethyl 2-(2H-1,2,3-triazol-2-yl)acetate (7.8 g, 50 mmol), and the reaction was stirred for 18 h at room temperature. 2. Upon completion of the reaction, the reaction mixture was acidified with 2M hydrochloric acid (150 mL) followed by extraction with dichloromethane (150 mL x 3). 3. The organic phases were combined, dried over magnesium sulfate and concentrated under reduced pressure to afford 2H-2-acetic acid-1,2,3-triazole as a white solid in 81% (5.2 g) yield. 4. 4. Product characterization: 1H NMR (400 MHz, CDCl3) δ: 5.35 (s, 2H), 7.72 (s, 2H); LRMS APCI m/z 128 [M + H]+.

References

[1] Patent: WO2006/123242, 2006, A1. Location in patent: Page/Page column 35

2H-1,2,3 Triazole-2-acetic acid Preparation Products And Raw materials

2H-1,2,3 Triazole-2-acetic acid Suppliers

Global Suppliers ( 55)
Supplier Tel Email Country ProdList Advantage
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
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Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
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DebyeTec.com Inc. 18086626237 18086626237 2693528373@qq.com China 2936 56

2H-1,2,3 Triazole-2-acetic acid Spectrum

2-(2H-1,2,3-triazol-2-yl)acetic acid AP8Impurity 2H-1,2,3 Triazole-2-acetic acid 4320-91-6