5-Fluoro-2-methoxynicotinic acid
- CAS No.
- 884494-82-0
- Chemical Name:
- 5-Fluoro-2-methoxynicotinic acid
- Synonyms
- 5-FLUORO-2-METHOXYNICOTINIC ACID;5-Fluoro-2-methoxypyridine-3-carboxylic acid;3-Pyridinecarboxylicacid, 5-fluoro-2-methoxy-;5-Fluoro-2-methoxynicotinic acid ISO 9001：2015 REACH;5-Fluoro-2-methoxypyridine-3-carboxylic acid, 3-Carboxy-5-fluoro-2-methoxypyridine
- CBNumber:
- CB4458782
- Molecular Formula:
- C7H6FNO3
- Molecular Weight:
- 171.13
- MDL Number:
- MFCD04972399
- MOL File:
- 884494-82-0.mol
- MSDS File:
- SDS
| Boiling point | 283.7±35.0 °C(Predicted) |
|---|---|
| Density | 1.386±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 3.02±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C7H6FNO3/c1-12-6-5(7(10)11)2-4(8)3-9-6/h2-3H,1H3,(H,10,11) |
| InChIKey | WMTDYCWMCDHQHR-UHFFFAOYSA-N |
| SMILES | C1(OC)=NC=C(F)C=C1C(O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| WGK Germany | WGK 3 |
| HS Code | 2933399990 |
| Storage Class | 11 - Combustible Solids |
5-Fluoro-2-methoxynicotinic acid price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC10656 | 5-Fluoro-2-methoxynicotinic acid 98% | 884494-82-0 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC10656 | 5-Fluoro-2-methoxynicotinic acid 98% | 884494-82-0 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC10656 | 5-Fluoro-2-methoxynicotinic acid 98% | 884494-82-0 | 1g | $37 | 2026-06-04 | Buy |
| Apolloscientific | PC10656 | 5-Fluoro-2-methoxynicotinic acid 98% | 884494-82-0 | 5g | $142 | 2026-06-04 | Buy |
| Matrix Scientific | 104391 | 5-Fluoro-2-methoxynicotinic acid | 884494-82-0 | 1.00g | $34 | 2026-05-18 | Buy |
5-Fluoro-2-methoxynicotinic acid Chemical Properties,Uses,Production
Uses
5-Fluoro-2-methoxynicotinic acid is used as a pharmaceutical and chemical intermediate.
Synthesis
351410-62-3
884494-82-0
In a round-bottomed flask, 5-fluoro-2-methoxypyridine-3-carbaldehyde (37, 0.500 g, 3.22 mmol) was dissolved in a solvent mixture of 30 mL of 1,4-dioxane and 10 mL of water, to which was added sodium chlorite (0.6734 g, 5.957 mmol) and sulfamic acid (2.39 g, 24.6 mmol) in that order. The reaction mixture was stirred at room temperature for 5 min and then poured into 100 mL of water and extracted with 100 mL of ethyl acetate. The organic layer was washed with water and brine sequentially, dried over anhydrous magnesium sulfate, filtered and the filtrate was concentrated in vacuum to give the crude product 5-fluoro-2-methoxynicotinic acid (150, 512 mg), which was used directly in the subsequent reaction.
References
[1] Patent: US9096593, 2015, B2. Location in patent: Page/Page column 321; 322
5-Fluoro-2-methoxynicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| nanjing dingda Pharmatech. co. ltd | 18013843276 | 1642441764@qq.com | China | 152 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3836 | 58 |
| Tianjin Jinyuda Chemical Co., Ltd. | 022-58013646 13011382049 | sales@jinyudachem.com | China | 1976 | 55 |
| Wuhan Taiyicheng Biopharmaceutical Co., Ltd. | 027-88320699 | tycshyy@126.com | China | 297 | 66 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3544 | 55 |
View Lastest Price from 5-Fluoro-2-methoxynicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 5-fluoro-2-methoxynicotinic acid
884494-82-0
|
$2.00-6.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-08-20 | 5-Fluoro-2-methoxynicotinic acid
884494-82-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-12 | 5-Fluoro-2-methoxynicotinic acid
884494-82-0
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 5-fluoro-2-methoxynicotinic acid
884494-82-0
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 5-Fluoro-2-methoxynicotinic acid
884494-82-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-Fluoro-2-methoxynicotinic acid
884494-82-0
- $1.00
- 99%
- Career Henan Chemical Co
