L-SELENOCYSTINE
- CAS No.
- 29621-88-3
- Chemical Name:
- L-SELENOCYSTINE
- Synonyms
- H-Se-Cystine-OH;L-SELENOCYSTINE 98%;L-SELENOCYSTINE;SELENO-L-CYSTINE;L-Selenocystine,98%;Seleno-L-cystine 95%;3’-diselenodi-l-alanin;3,3'-DISELENO-L-ALANINE;l-3,3’-diselenodialanine;Seleno-
L -cystine
- CBNumber:
- CB4464888
- Molecular Formula:
- C6H12N2O4Se2
- Molecular Weight:
- 334.09
- MDL Number:
- MFCD00800971
- MOL File:
- 29621-88-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 224.5-229.5 °C (lit.) |
|---|---|
| Boiling point | 538.3±60.0 °C(Predicted) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly) |
| pka | 1.69±0.10(Predicted) |
| form | Powder |
| color | Yellow |
| optical activity | [α]20/D 28°, c = 1 in NaOH |
| BRN | 1969559 |
| Stability | Hygroscopic |
| Major Application | peptide synthesis |
| InChI | 1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1 |
| InChIKey | JULROCUWKLNBSN-IMJSIDKUSA-N |
| SMILES | N[C@@H](C[Se][Se]C[C@H](N)C(O)=O)C(O)=O |
| EWG's Food Scores | 1 |
| FDA UNII | 261B157KR8 |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H331-H373-H410 | |||||||||
| Precautionary statements | P273-P301+P310+P330-P304+P340+P311-P314 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 23/25-33-50/53 | |||||||||
| Safety Statements | 20/21-28-45-60-61 | |||||||||
| RIDADR | UN 3283 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AY6032000 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Inhalation Acute Tox. 3 Oral Aquatic Acute 1 Aquatic Chronic 1 STOT RE 2 |
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| NFPA 704 |
|
L-SELENOCYSTINE price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 545996 | Seleno-L-cystine 95% | 29621-88-3 | 250mg | $176 | 2026-04-30 | Buy |
| Sigma-Aldrich | 545996 | Seleno-L-cystine 95% | 29621-88-3 | 1g | $300 | 2026-04-30 | Buy |
| TCI Chemical | E1368 | L-Selenocystine | 29621-88-3 | 250MG | $88 | 2026-04-30 | Buy |
| Cayman Chemical | 17793 | L-Selenocystine ≥90% | 29621-88-3 | 50mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17793 | L-Selenocystine ≥90% | 29621-88-3 | 100mg | $68 | 2026-04-30 | Buy |
L-SELENOCYSTINE Chemical Properties, Uses, Production
Description
L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.
Chemical Properties
yellow fine powder
Uses
Seleno-L-cystine can be used for the synthesis of:
- Biologically active selenol compounds.
- Non-natural selenylated diamino acids.
reaction suitability
reaction type: solution phase peptide synthesis
References
[1] SPALLHOLZ J E. On the nature of selenium toxicity and carcinostatic activity[J]. Free Radical Biology and Medicine, 1994, 17 1: Pages 45-64. DOI: 10.1016/0891-5849(94)90007-8
[2] SOUGAT MISRA. Redox-active selenium compounds–from toxicity and cell death to cancer treatment.[J]. Nutrients, 2015, 7 5: 3536-3556. DOI: 10.3390/nu7053536
[3] BRIAN CUNNIFF . A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates[J]. Analytical biochemistry, 2013, 443 1: Pages 34-40. DOI: 10.1016/j.ab.2013.08.013
[4] MARITA WALLENBERG. Selenium induces a multi-targeted cell death process in addition to ROS formation[J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2014, 18 4: 671-684. DOI: 10.1111/jcmm.12214
L-SELENOCYSTINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alabiochem Tech.Co., Ltd. | 512-58900862 400-0707518 | sales@alabiochem.com | China | 988 | 59 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Chembon Pharmaceutical Co., Ltd. | 028-84252981 18583719936 | sales@chembon.com.cn | China | 854 | 64 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
View Latest Price from L-SELENOCYSTINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | L-Selenocystine
29621-88-3
|
$31.00-54.00 | 99.88% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-02-13 | selenocystine
29621-88-3
|
$1.00 | 1g | 98% | 1000 | Apeloa production Co.,Limited | |
 |
2020-03-06 | L-SELENOCYSTINE
29621-88-3
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- L-Selenocystine
29621-88-3
- $31.00-54.00
- 99.88%
- TargetMol Chemicals Inc.
-
- selenocystine
29621-88-3
- $1.00
- 98%
- Apeloa production Co.,Limited
-
- L-SELENOCYSTINE
29621-88-3
- $1.00
- 99%
- Career Henan Chemical Co
