Prallethrin | 23031-36-9

Prallethrin Properties

Melting point	25°C
Boiling point	381.62°C (rough estimate)
Density	d420 1.03
vapor pressure	﹤4.3×10^-5 Pa (23.1 °C)
refractive index	1.4200 (estimate)
Flash point	139 °C
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly)
Water Solubility	8 mg l^-1 (25 °C)
Henry's Law Constant	6.2×10⁰ mol/(m³Pa) at 25℃, HSDB (2015)
Stability	Stable. Incompatible with strong oxidizing agents.
Major Application	agriculture environmental
InChI	1S/C19H24O3/c1-7-8-13-12(4)16(10-15(13)20)22-18(21)17-14(9-11(2)3)19(17,5)6/h1,9,14,16-17H,8,10H2,2-6H3
InChIKey	SMKRKQBMYOFFMU-UHFFFAOYSA-N
SMILES	C\C(C)=C/C1C(C(=O)OC2CC(=O)C(CC#C)=C2C)C1(C)C
CAS DataBase Reference	23031-36-9(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	2X67A9B2Z7
EPA Substance Registry System	Prallethrin (23031-36-9)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06,GHS09
Signal word	Danger
Hazard statements	H302-H331-H410
Precautionary statements	P261-P264-P270-P273-P301+P312-P304+P340+P311
PPE	Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes	T,N
Risk Statements	22-23-50/53
Safety Statements	45-60-61
RIDADR	UN2811 6.1/PG 2
WGK Germany	3
HS Code	29162090
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 3 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1
Hazardous Substances Data	23031-36-9(Hazardous Substances Data)
Toxicity	mouse,LD50,oral,190mg/kg (190mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 228, 1989.

Prallethrin price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	32917	Prallethrin PESTANAL	23031-36-9	100mg	$256	2026-04-30	Buy
Cayman Chemical	25813	Prallethrin ≥90%(mixtureofdiastereomers)	23031-36-9	25mg	$69	2026-04-30	Buy
Cayman Chemical	25813	Prallethrin ≥90%(mixtureofdiastereomers)	23031-36-9	50mg	$130	2026-04-30	Buy
Cayman Chemical	25813	Prallethrin ≥90%(mixtureofdiastereomers)	23031-36-9	100mg	$246	2026-04-30	Buy
Cayman Chemical	25813	Prallethrin ≥90%(mixtureofdiastereomers)	23031-36-9	250mg	$546	2026-04-30	Buy

Product number	Packaging	Price	Buy
32917	100mg	$256	Buy
25813	25mg	$69	Buy
25813	50mg	$130	Buy
25813	100mg	$246	Buy
25813	250mg	$546	Buy

Prallethrin Chemical Properties, Uses, Production

Chemical properties

The original medicine is an oil like liquid. At b.p.>313.5℃ , the relative density is 1.03. It is easy to dissolve in methanol and hexane. The solubility is >50% at normal temperature, The solubility in the water at 25 C is 8.03mg/L, The distribution coefficient is 30800.

Application

The product characteristics of fenvalerate are the same as those of fenpropathrin with strong contact toxicity. The knockdown and killing performance is 4 times higher than that of the right-handed trans pyrethrin, and has a prominent driving effect on cockroaches. It is mainly used for processing mosquito repellent incense, electric mosquito repellent incense, liquid mosquito repellent incense and spray to control household pests such as housefly, mosquito, louse, cockroach etc. The recommended amount of use is as follows: (with effective ingredients) mosquito repellent incense: The electric heat mosquito incense containing 0.05% of the product: Containing 10mg/ tablets of this product to control the temperature of the electric heater center at 125-135℃. Liquid mosquito repellent incense: containing 0.66% of this product, plus proper stabilizer; Sustained-release agent; Aerosols: 0.05 0.2% of this product with appropriate amount of lethal agent, synergist and emulsifier.

Chemical Properties

solid

Uses

Prallethrin ia a synthetic pyrethroid; propynyl analog of allethrin. Prallethrin is used as an insecticide.

Uses

Prallethrin is used for the control of insects in domestic and public health situations.

Definition

ChEBI: Prallethrin is a member of cyclopropanes and a terminal acetylenic compound. It has a role as a pyrethroid ester insecticide and an agrochemical. It is functionally related to a chrysanthemic acid.

Production Methods

Prallethrin is synthesised through a multi-step chemical process rooted in pyrethroid chemistry, specifically involving the esterification of chrysanthemic acid derivatives with alcohols. The key intermediate is a cyclopropane carboxylic acid, which is reacted with a substituted cyclopentenol, often containing a propargyl group, to form the final ester compound. This reaction is carefully controlled to yield the desired cis-trans isomeric mixture, which is crucial for prallethrin’s insecticidal potency. The process emphasises high purity and precise stereochemistry, as impurities can affect both efficacy and safety.

Hazard

A poison by ingestion and inhalation. Low toxicity by skin contact.

Mechanism of action

Contact, with rapid knock down effect, acts on the insects nervous system. Sodium channel modulator.

Pharmacology

Prallethrin is a propynyl analog of allethrin, with 2-methyl-4-oxo-3-(prop-2-ynyl)-cyclopent-2-enyl as the secondary alcohol moiety that has been introduced against public health pests (113–115). The ester of the (S)-alcohol with (1R)-trans,cis-chrysanthemic acid resolved partially is commercialized on the strength of the assessment of insecticidal action of individual stereoisomers (116). Compared with d-allethrin, it is approximately four, six, and five times more effective on Musca domestica (for killing), Blattella germanica (for killing), and Culex pipiens pallens (for knockdown), respectively (43). A lower level of resistance to prallethrin than to phenoxybenzyl pyrethroids was demonstrated in a kdr-resistant housefly strain (116).

Safety Profile

A poison by ingestion and inhalation. Low toxicity by skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.

Metabolic pathway

Prallethrin is stable under normal room temperature storage conditions for up to 36 months. It is labile to alkali at the ester linkage, forming 2 and 3 (Scheme 1). Analogy with the allethrins (from which it differs only in the degree of unsaturation in the side chain - propyne rather than propene) would suggest that the compound is very photolabile.

Degradation

The metabolism of prallethrin was studied following single oral administration and subcutaneous injection of the cis- and trans-isomers to rats at two dose levels and after repeated dosing. The compound was labelled in the alcohol moiety (inferred from the results) (PSD, 1995).
Absorption was rapid with maximum tissue residues being attained 3 hours after the dosing of each isomer. Biphasic clearance of radioactivity then occurred with half-lives of 3 and 14-23 hours (cis-isomer) and 3-5 and 7-35 hours (trans-isomer). Urinary excretion accounted for 13-32% (cis-isomer) and 45-62% (trans-isomer) of the dose with most of the balance in the faeces. Less than 0.1% was exhaled as ¹⁴CO₂ . Residues in tissues were very low (0.3% of the dose at 7 days). Metabolism and disposition were independent of dose and dose route but residues in tissues were somewhat higher for the cis-isomer.
Twenty-one metabolites were identified (taking account of stereochemistry and conjugates). The major pathways of metabolism involved oxidation at a methyl group of the isobutenyl group in the acid moiety (giving 4 and 5), at the C1 and C2 positions of the propynyl group in the alcohol moiety (giving 6 and 9) and dihydroxylation (to 7 and 8). The resulting hydroxy derivatives were conjugated with glucuronic acid and sulfate.
Hydrolysis of prallethrin also occurred to afford the acid 2 (presumed) and the alcohol 3. Hydrolysis of the hydroxylated prallethrins and further oxidation of 3 afforded 10 and 11. Further oxidation of 10 to the cyclic tertiary alcohol (12) was observed.
When bluegill sunfish were exposed to a l4C-labelled (acid and alcohol groups) prallethrin isomer (1Rtrans), more than 50% of the biliary radioactivity recovered from the gall bladder was observed as one ester metabolite. This was identified as the taurine conjugate of carboxylic acid metabolite 5 (Oshima et al., 1992).

Pesticide Type

Insecticide; Veterinary substance

Prallethrin Preparation Products And Raw materials

Raw materials

Ethyl acetoacetate Methylglyoxal Ethanol N,N-Dimethylformamide Propargyl benzenesulfonate

Sodium ethoxide Acetylacetone 6-Heptynoic acid 1-Hexyne Ethyl acetate

CHAMAZULEN

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Preparation Products

Prallethrin Suppliers

Global Suppliers ( 155)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11674	57
UHN Shanghai Research & Development Co., Ltd.	021-58958002 18930822973	sales@uhnshanghai.com	China	997	58
The future of Shanghai Industrial Co., Ltd.	021-61552785	sales@shshiji.com	China	9531	55
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810 18652991625	sales@sunlidabio.com	China	3223	55
Shanghai JONLN Reagent Co., Ltd.	400-0066400 13621662912	422131432@qq.com	China	9970	55
TianJin Alta Scientific Co., Ltd.	022-65378550-8551	contact@altascientific.com	China	2772	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
ShangHai DEMO Chemical Co.,Ltd	57
Chemsky（shanghai）International Co.,Ltd.	50
Syntechem Co.,Ltd	57
Sichuan Kulinan Technology Co., Ltd	57
UHN Shanghai Research & Development Co., Ltd.	58
The future of Shanghai Industrial Co., Ltd.	55
Nanjing Sunlida Biological Technology Co., Ltd.	55
Shanghai JONLN Reagent Co., Ltd.	55
TianJin Alta Scientific Co., Ltd.	58

View Latest Price from Prallethrin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-30	Prallethrin 23031-36-9		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2026-05-28	Prallethrin 23031-36-9	$10.60	1KG	98%	5000kg	Hebei Chuanghai Biotechnology Co,.LTD
2025-06-27	Prallethrin 23031-36-9		1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

Prallethrin
23031-36-9
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

Prallethrin
23031-36-9
$10.60
98%
Hebei Chuanghai Biotechnology Co,.LTD

Prallethrin
23031-36-9
$0.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

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s-4068sf trans-(+-)-ydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-on (RS)-2-Methyl-4-oxo-3-prop-2-ynylcyclopent-2-enyl (1RS,3RS:1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate 2-methyl-4-oxo-3-prop-2-ynylcyclopent-2-enyl-2,2-dimethyl-3-(2-methylprop-1-enyl) cyclopropanecarboxylate Pralle 2,2-Dimethyl-3-(2-methyl-1-propen-1-yl)-1-cyclopropanecarboxylic acid 2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl ester 2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid 2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl ester Rethrinpropargyl S-4068 forte 2,2-DiMethyl-3-(2-Methyl-1-propen-1-yl)cyclopropanecarboxylic Acid 2-Methyl-4-oxo-3-(2-propyn-1-yl)-2-cyclopenten-1-yl Ester Acetylene C PerMethrin trans-(±)-4-Hydroxy- 3-Methyl-2-(2-propynyl)-2-cyclopenten-1-one 2,2-DiMethyl-3-(2-Methylpropenyl) cyclopropanecarboxylate, (8CI) Prallethrin 10mg [23031-36-9] 2-Methyl-4-oxo-3-(prop-2-yn-1-yl)cyclopent-2-en-1-yl 2,2-diMethyl-3-(2-Methylprop-1-en-1-yl)cyclopropanecarboxylate Prallethrin (Mixture of diastereoMers) (S)-2-METHYL-4-OXO-3-(2-PROPYNYL)-CYCLOPENT-1-YL (1R)-CIS-TRANS-CHRYSANTHEMATE (S)-2-METHYL-4-OXO-3-PROP-2-YNYLCYCLOPENT-1-YL(1R)-CIS,TRANS-2,2-DIMETHYL-3-(2-METHYLPROP-1-ENYL)-CYCLOPROPANECARBOXYLATE PRALLETHRIN NYLAR(R) (RS)-2-methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl(1RS)-cis,trans-chrysanthemate Prallethrin 0 (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-enyl)-1-cyclopropanecarboxylic acid [(1R)-2-methyl-4-oxo-3-prop-2-ynyl-1-cyclopent-2-enyl] ester D-Trans-Prallethrin 2-Methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate prallethrin (bsi,draft e-iso9, prallethrine (draft f-iso)etoc PRALLETHRIN,RICH-D-TRANS 2,2-Dimethyl-3-(2-methylprop-1-enyl)-cyclopropanecarboxylate 2-Methyl-4-oxo-3-(prop-2-ynyl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate ETOC(R) CYCLOPROPANECARBOXYLIC ACID, 2,2-DIMETHYL-3-(2-METHYL-1-PROPENYL)-(1S)-2-METHYL-4-OXO-3-(2-PROPENYL)-2-CYCLOPENTEN-1-YL ESTER, (1R) prallethrin ETOC 2-methyl-4-oxo-3-(prop-2-ynyl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate 2,2-dimethyl-3-(2-methylpropenyl)-,esterwith4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-oCyclopropanecarboxylicacid 2-dimethyl-3-(2-methylpropenyl)-esterwith4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopenten-1-onecyclopropanecarboxylicaci 2-Methyl-4-oxo-3-(2-propynyl)cyclopent-2-enyl(1R)-cis,trans-chrysanthemate ai3-29750 d,d-t80-prallethrin s4068 Prallethrin @100 μg/mL in Methanol Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 2-methyl-4-oxo-3-(2-propyn-1-yl)-2-cyclopenten-1-yl ester Prallethrin(Mixture of diastereom) Prallethrin 10.0 μg/ml Acetonitrile 2-methyl-4-oxo-3-(prop-2-ynyl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate (Prallethrin) Propathrin Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propynyl)-2-cyclopenten-1-yl ester ETOC 23031-36-9 Agro-Products INSECTICIDE