22-(tert-Butoxy)-22-oxodocosanoic acid
- CAS No.
- 1642333-05-8
- Chemical Name:
- 22-(tert-Butoxy)-22-oxodocosanoic acid
- Synonyms
- 22-(tert-butoxy)-22-oxoicosanoic acid;22-(tert-Butoxy)-22-oxodocosanoic acid;Docosanedioic acid, 1-(1,1-dimethylethyl) ester;Docosanedioic acid, mono(1,1-dimethylethyl) ester
- CBNumber:
- CB44798433
- Molecular Formula:
- C26H50O4
- Molecular Weight:
- 426.67
- MDL Number:
- MFCD30830215
- MOL File:
- 1642333-05-8.mol
| Product description | Number | Pack Size | Price |
| 22-(tert-Butoxy)-22-oxodocosanoic acid | 2123-1-87 | 250mg | $600 |
| 22-(tert-Butoxy)-22-oxodocosanoicacid 97% | AS145122 | 1g | $1348 |
| 22-(tert-Butoxy)-22-oxodocosanoicacid 97% | A971470 | 100g | $2534 |
| 22-(tert-Butoxy)-22-oxodocosanoicacid 98+% | A1490292 | 100g | $2534 |
| 22-(tert-Butoxy)-22-oxodocosanoicacid 98+% | A1490292 | 25g | $774 |
| storage temp. | Storage temp. 2-8°C |
|---|---|
| form | powder |
| color | White |
| InChI | InChI=1S/C26H50O4/c1-26(2,3)30-25(29)23-21-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-22-24(27)28/h4-23H2,1-3H3,(H,27,28) |
| InChIKey | OXPWLSZVTHVKQN-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCCCCCC(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P301+P312-P261 |
| HS Code | 2917198090 |
22-(tert-Butoxy)-22-oxodocosanoic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| SynQuest Laboratories | 2123-1-87 | 22-(tert-Butoxy)-22-oxodocosanoic acid | 1642333-05-8 | 250mg | $600 | 2021-12-16 | Buy |
| Activate Scientific | AS145122 | 22-(tert-Butoxy)-22-oxodocosanoicacid 97% | 1642333-05-8 | 1g | $1348 | 2021-12-16 | Buy |
| Ambeed | A971470 | 22-(tert-Butoxy)-22-oxodocosanoicacid 97% | 1642333-05-8 | 100g | $2534 | 2021-12-16 | Buy |
| Ambeed | A1490292 | 22-(tert-Butoxy)-22-oxodocosanoicacid 98+% | 1642333-05-8 | 100g | $2534 | 2021-12-16 | Buy |
| Ambeed | A1490292 | 22-(tert-Butoxy)-22-oxodocosanoicacid 98+% | 1642333-05-8 | 25g | $774 | 2021-12-16 | Buy |
22-(tert-Butoxy)-22-oxodocosanoic acid Chemical Properties,Uses,Production
Uses
22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t
IC 50
Non-cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. DOI:10.1038/nrd.2016.268
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
22-(tert-Butoxy)-22-oxodocosanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
22-(tert-Butoxy)-22-oxodocosanoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Protheragen-ING | +16313385890 | info@protheragen-ing.com | United States | 3868 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Anhuyan (Hainan) Biotechnology Co., LTD | +86-18163349544; +8618163349544 | mollylucking@foxmail.com | China | 3000 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
| Changsha Morning Shine Co., Ltd. | +8613751227286 | chenkaijie@csmspharm.com | China | 300 | 58 |
| Zhengzhou anmousse chemical products co. LTD | 0371-55289822 18737195735 | 483339295@qq.com | China | 7292 | 58 |
| Nanjing Machido Pharmaceutical Technology Co., Ltd. | 19556085883 | sales@machidopharma.com | China | 396 | 58 |
