ChemicalBook >> CAS DataBase List >>VL285
VL285
- CAS No.
- 1448188-57-5
- Chemical Name:
- VL285
- Synonyms
- VL285;VL285, 10 mM in DMSO;VL-285; VL 285; VL285;E3 ligase-recruiting Moiety,VL-285,Ligands for E3 Ligase,Inhibitor,inhibit,VL285,VL 285;(2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, 1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-
- CBNumber:
- CB44812456
- Molecular Formula:
- C29H32N4O4S
- Molecular Weight:
- 532.65
- MDL Number:
- MOL File:
- 1448188-57-5.mol
Last updated:2025-04-18 09:52:19
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
VL285 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb573256 | VL-285 >98% | 1448188-57-5 | 100mg | $1431.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573256 | VL-285 >98% | 1448188-57-5 | 250mg | $2541.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573256 | VL-285 >98% | 1448188-57-5 | 1g | $5062.6 | 2021-12-16 | Buy |
| DC Chemicals | DC12676 | VL-285 >98% | 1448188-57-5 | 1g | $3400 | 2021-12-16 | Buy |
| Ambeed | A1142888 | VL285 98% | 1448188-57-5 | 1mg | $69 | 2021-12-16 | Buy |
VL285 Chemical Properties,Uses,Production
Uses
VL285 is a potent VHL ligand with an IC50 of 0.34 μM[1].
IC 50
VHL
References
[1] Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7. DOI:10.1021/acschembio.5b00442
VL285 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 57)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
VL285
VL-285; VL 285; VL285
2-Pyrrolidinecarboxamide, 1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-
(2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide
(2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
E3 ligase-recruiting Moiety,VL-285,Ligands for E3 Ligase,Inhibitor,inhibit,VL285,VL 285
VL285, 10 mM in DMSO
1448188-57-5