Chloromethanesulfonyl chloride
- CAS No.
- 3518-65-8
- Chemical Name:
- Chloromethanesulfonyl chloride
- Synonyms
- CHLOROMESYL CHLORIDE;CHLOROMETHYLSULFONYL CHLORIDE;CMSC;RARECHEM AW HA 0004;Chlormethansulfochlorid;Chlormethansulfonylchlorid;CHLORMETHYLSULFONYL CHLORIDE;chloro-methanesulfonylchlorid;Chloromethylsulphonylchloride;CHLOROMETHANESULFONYL CHLORIDE
- CBNumber:
- CB4492126
- Molecular Formula:
- CH2Cl2O2S
- Molecular Weight:
- 149
- MDL Number:
- MFCD00014727
- MOL File:
- 3518-65-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 80-81°C |
|---|---|
| Density | 1.64 g/mL at 20 °C(lit.) |
| refractive index | 1.488 |
| Flash point | 110.00°C |
| storage temp. | -20°C |
| solubility | Chloroform, Methanol |
| form | Liquid |
| Specific Gravity | 1.67 |
| color | White |
| Water Solubility | It is soluble in dichloromethane, pyridine, and most organic solvents. It is insoluble in water. |
| Sensitive | Moisture Sensitive |
| BRN | 1811761 |
| InChI | 1S/CH2Cl2O2S/c2-1-6(3,4)5/h1H2 |
| InChIKey | KQDDQXNVESLJNO-UHFFFAOYSA-N |
| SMILES | ClCS(Cl)(=O)=O |
| CAS DataBase Reference | 3518-65-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 7WRW5VDZ79 |
| NIST Chemistry Reference | Chloromethanesulfonyl chloride(3518-65-8) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,Xi | |||||||||
| Risk Statements | 22-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | PB2800000 | |||||||||
| F | 10-21 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | I | |||||||||
| HS Code | 2904990090 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Corr. 1B |
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| NFPA 704 |
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Chloromethanesulfonyl chloride price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 93479 | Chloromethanesulfonyl chloride technical, ≥90% (AT) | 3518-65-8 | 5G | $104 | 2026-04-30 | Buy |
| TCI Chemical | C0924 | Chloromethylsulfonyl Chloride >95.0%(T) | 3518-65-8 | 5g | $68 | 2026-04-30 | Buy |
| TCI Chemical | C0924 | Chloromethylsulfonyl Chloride >95.0%(T) | 3518-65-8 | 25g | $224 | 2026-04-30 | Buy |
| Usbiological | 267417 | Chloromethanesulfonyl chloride Asreported | 3518-65-8 | 5g | $396 | 2026-06-03 | Buy |
| Usbiological | 267417 | Chloromethanesulfonyl chloride Asreported | 3518-65-8 | 10g | $546 | 2026-06-03 | Buy |
Chloromethanesulfonyl chloride Chemical Properties,Uses,Production
Uses
Chloromethanesulfonyl Chloride is a very useful intermediate for organic synthesis. It enhances citric acid production by Aspergillus niger NCIM-1696 and increases the yield of citric acid. It also functions as a useful intermediate for pharmaceutical synthesis.
Synthesis
Chloromethylsulfonyl chloride is synthesized as follows: add Na2SO3252g, 500g of water, 504g of methylene chloride, I1.25g of cetyltrimethylammonium chloride to 2000ml of the reactor with a pressure and temperature detecting device, warm up to 0.2MPa pressure in the reactor and keep pressure to react for 3hr, stop the reaction, cool down, unload the reactor and remove the water and unreacted solvent by distillation. Unreacted solvent was removed by distillation and dried to obtain the product I260 g. Yield: 95%.
The above synthesized product I was added to 2000 ml reaction bottle with thermometer, drying and distillation device, add methanol 260g, triethylamine 1.04g, slowly raise the temperature to T = 40 , maintain the temperature, in 30min, through the chlorine gas 13g, keep warm to react 3.5hr, the end of the reaction. The solvent was removed by distillation. Obtained crude product, at a temperature of T = 70-80 , vacuum degree of 0.08-0.1MPa conditions, distillation, the product 240g. 85% yield.
Chloromethanesulfonyl chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Lastest Price from Chloromethanesulfonyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-12 | ChloroMethylsulfonyl Chloride
3518-65-8
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-13 | Chloromethanesulfonyl chloride
3518-65-8
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- ChloroMethylsulfonyl Chloride
3518-65-8
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- Chloromethanesulfonyl chloride
3518-65-8
- $9.80
- ≥98%
- Career Henan Chemical Co
