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Ethanesulfonyl chloride

Ethanesulfonyl chloride structure

CAS No.: 594-44-5

Chemical Name:: Ethanesulfonyl chloride

Synonyms: ethanesulflonyl chloride;tl77;TL 77;Ethylsulfochloride;Ethane sulfochloride;1,2-Ethane-disulfonic;ethylsulfurylchloride;Tirofiban Impurity 72;Ethyl sulfone chloride;ETHYLSULFONYL CHLORIDE

CBNumber:: CB0461854

Molecular Formula:: C2H5ClO2S

Molecular Weight:: 128.58

MDL Number:: MFCD00007460

MOL File:: 594-44-5.mol

MSDS File:: SDS

Last updated:2026-06-22 17:37:45

Product description	Number	Pack Size	Price
Ethanesulfonyl chloride ≥99%	471542	100ml	$102
Ethanesulfonyl chloride ≥99%	471542	500ml	$376
Ethanesulfonyl Chloride >98.0%(T)	E0035	25g	$26
Ethanesulfonyl Chloride >98.0%(T)	E0035	250g	$179
Ethanesulfonyl chloride	FE138684	0.5kg	$900
More product size

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Ethanesulfonyl chloride Properties

Melting point	-70°C
Boiling point	177 °C (lit.)
Density	1.357 g/mL at 25 °C (lit.)
refractive index	n20/D 1.452(lit.)
Flash point	182 °F
storage temp.	Inert atmosphere,2-8°C
solubility	soluble in dichloromethane,Ether
form	Liquid
color	Clear colorless to light yellow or light brownish to pinkish-purple
Water Solubility	DECOMPOSES
Sensitive	Moisture Sensitive
BRN	773865
InChI	1S/C2H5ClO2S/c1-2-6(3,4)5/h2H2,1H3
InChIKey	FRYHCSODNHYDPU-UHFFFAOYSA-N
SMILES	CCS(Cl)(=O)=O
CAS DataBase Reference	594-44-5(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	B56ZOC898A
NIST Chemistry Reference	Ethanesulfonyl chloride(594-44-5)
EPA Substance Registry System	Ethanesulfonyl chloride (594-44-5)
UNSPSC Code	12352107
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS06

Signal word

Danger

Hazard statements

H302+H312-H314-H330-H335

Precautionary statements

P260-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338

target organs

Respiratory system

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

21/22-23-34-22

Safety Statements

26-36/37/39-45

RIDADR

UN 2927 6.1/PG 2

WGK Germany

RTECS

KI8050000

19-21

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

HS Code

29049090

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 2 Inhalation
Acute Tox. 4 Dermal
Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1B
STOT SE 3

Hazardous Substances Data

594-44-5(Hazardous Substances Data)

REACH Registrations

Active

NFPA 704

	1
3		0

Ethanesulfonyl chloride price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	471542	Ethanesulfonyl chloride ≥99%	594-44-5	100ml	$102	2026-04-30	Buy
Sigma-Aldrich	471542	Ethanesulfonyl chloride ≥99%	594-44-5	500ml	$376	2026-04-30	Buy
TCI Chemical	E0035	Ethanesulfonyl Chloride >98.0%(T)	594-44-5	25g	$26	2026-04-30	Buy
TCI Chemical	E0035	Ethanesulfonyl Chloride >98.0%(T)	594-44-5	250g	$179	2026-04-30	Buy
Biosynth	FE138684	Ethanesulfonyl chloride	594-44-5	0.5kg	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
471542	100ml	$102	Buy
471542	500ml	$376	Buy
E0035	25g	$26	Buy
E0035	250g	$179	Buy
FE138684	0.5kg	$900	Buy

Ethanesulfonyl chloride Chemical Properties,Uses,Production

Chemical Properties

clear light brownish to pinkish-purple liquid

Uses

Chloroethylsulfone was used in discovery of a selective inhibitor of oncogenic B-raf kinase with potent antimelanoma activity.

Application

Ethanesulfonyl chloride can make sulfonyl-substituted imides, methide lithium salts, and pentafluoroethanesulfonyl fluoride, a fluorinated surfactant. It is an intermediate in synthesizing new, low-cost, non-fluorinated, sulfonyl-substituted imide and methide lithium salts and an intermediate in preparing the fluorinated surfactant pentafluoroethanesulfonyl fluoride.

Synthesis Reference(s)

Journal of the American Chemical Society, 61, p. 2548, 1939 DOI: 10.1021/ja01878a085

Hazard

Ethanesulphonyl chloride is harmful to humans; it is corrosive, irritant and acutely toxic. Contact may cause severe skin burns and eye damage, whilst inhalation may cause respiratory irritation and, in severe cases, may be fatal.

Ethanesulfonyl chloride synthesis

Synthesis of Ethanesulfonyl chloride from ETHANE

Ethanesulfonyl chloride Preparation Products And Raw materials

Raw materials

Sodium disulfide Ethylthiocyanate

Preparation Products

1-ETHYLSULFONYL-PIPERAZINE Methyl ethanesulfonate Ethanesulfonamide ABBV-075 Ethylicin

Methyl 4-ethanesulfonaMidobenzoate 2-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile 2-(1-(ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile 4-[(ETHYLSULFONYL)AMINO]BENZOIC ACID

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Ethanesulfonyl chloride Suppliers

Global( 344)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
JIANGXI TIME PHARMACEUTICAL CO.,LTD	+86-0794-7183888 +86-13155888520	sales@groupchem.com	China	27	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325	sales1@chuanghaibio.com	China	5215	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21533	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114	sales@amoychem.com	China	6339	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413	contact@trustwe.com	China	5757	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
Shouguang Nuomeng Chemical Co Ltd.	536-5119508	export@nuomengchem.com	China	46	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58

Supplier	Advantage
JIANGXI TIME PHARMACEUTICAL CO.,LTD	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
SIMAGCHEM CORP	58
Shouguang Nuomeng Chemical Co Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from Ethanesulfonyl chloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-25	Ethanesulfonyl chloride 594-44-5	$115.00	1KG	99% Min.		Shouguang Nuomeng Chemical Co Ltd.
2026-05-28	Ethanesulfonyl Chloride 594-44-5	$80.00-100.00	1KG	98%	10 ton	Hebei Chuanghai Biotechnology Co,.LTD
2026-03-20	Ethanesulfonyl chloride 594-44-5	$10.00	1KG	99%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd

Ethanesulfonyl chloride
594-44-5
$115.00
99% Min.
Shouguang Nuomeng Chemical Co Ltd.

Ethanesulfonyl Chloride
594-44-5
$80.00-100.00
98%
Hebei Chuanghai Biotechnology Co,.LTD

Ethanesulfonyl chloride
594-44-5
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

Ethanesulfonyl chloride Spectrum

Ethanesulfonyl chloride(594-44-5)MS Ethanesulfonyl chloride(594-44-5)¹HNMR Ethanesulfonyl chloride(594-44-5)IR1 Ethanesulfonyl chloride(594-44-5)Raman

594-44-5(Ethanesulfonyl chloride)Related Search:

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Potassium chloride Polyvinyl chloride Ethyl glycolate

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