Glycine-15N
- CAS No.
- 7299-33-4
- Chemical Name:
- Glycine-15N
- Synonyms
- [15N]GLYCINE;GLYCINE-15N;H-[15N]GLY-OH;[15N]-L-GLYCINE;15N,98%-Glycine;Glycine (1?N, 98%);Nitrogen-15 glycine;2-azanylacetic acid;2-azanylethanoic acid;Glycine-15N
- CBNumber:
- CB4494014
- Molecular Formula:
- C2H5NO2
- Molecular Weight:
- 76.08
- MDL Number:
- MFCD00064426
- MOL File:
- 7299-33-4.mol
- MSDS File:
- SDS
| Melting point | 240 °C (dec.)(lit.) |
|---|---|
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Aqueous Base (Slightly, Sonicated, Heated), Water (Sparingly) |
| form | Solid |
| color | White to Off-White |
| BRN | 1853034 |
| InChI | 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)/i3+1 |
| InChIKey | DHMQDGOQFOQNFH-LBPDFUHNSA-N |
| SMILES | [15NH2]CC(O)=O |
| UNSPSC Code | 12352209 |
| NACRES | NA.12 |
| CAS Number Unlabeled | 56-40-6 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| HS Code | 28459000 |
| Storage Class | 11 - Combustible Solids |
Glycine-15N price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 299294 | Glycine-15N 98 atom % | 7299-33-4 | 250mg | $124 | 2026-04-30 | Buy |
| Sigma-Aldrich | 299294 | Glycine-15N 98 atom % | 7299-33-4 | 1g | $266 | 2026-04-30 | Buy |
| Usbiological | 451331 | Glycine-15N | 7299-33-4 | 10mg | $319 | 2026-06-03 | Buy |
| Usbiological | 451331 | Glycine-15N | 7299-33-4 | 50mg | $425 | 2026-06-03 | Buy |
| TRC | TRC-G615989-50MG | Glycine-15N | 7299-33-4 | 50mg | $130 | 2026-06-03 | Buy |
Glycine-15N Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Glycine-15N is the labelled form of Glycine (G615990). Glycine is a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Biological Activity
Glycine-15N is the 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1].
IC 50
NMDA Receptor
References
[1] EDWARD M RUSSAK Edward M B. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals.[J]. Annals of Pharmacotherapy, 2019, 53 2: 211-216. DOI:10.1177/1060028018797110.
[2] W. GREENAWAY F. R W. A convenient synthesis of creatine-15N from glycine-15N via sarcosine-15N[J]. Journal of labelled compounds & radiopharmaceuticals, 1978, 14 4: 611-615. DOI:10.1002/jlcr.2580140417.
[3] HE J, ZHANG X, HE Q, et al. Synthesis of 15N-labeled heterocycles via the cleavage of C–N bonds of anilines and glycine-15N†[J]. Chemical Communications, 2021, 44: 5442-5445. DOI:10.1039/D1CC01734A.
[4] T P STEIN. Measurement of protein synthesis rates with [15N]glycine.[J]. American Journal of Physiology, 1980, 239 4: E294-E300. DOI:10.1152/ajpendo.1980.239.4.E294.
[5] MOSTAFA OTHMAN. Millimeter-Sized Clusters of Triple Cation Perovskite Enables Highly Efficient and Reproducible Roll-to-Roll Fabricated Inverted Perovskite Solar Cells[J]. Advanced Functional Materials, 2021, 32 12. DOI:10.1002/adfm.202110700.
Glycine-15N Preparation Products And Raw materials
Glycine-15N Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai Xilong Biochemical Technology Co., Ltd. | 021-52907766-8042 | China | 9928 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
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