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APC4

CAS No.
682794-85-0
Chemical Name:
APC4
Synonyms
APC4;1H-Indole-3-ethanamine, N-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-pyrimidinyl]-
CBNumber:
CB45388136
Molecular Formula:
Molecular Weight:
372.42
MDL Number:
MOL File:
682794-85-0.mol
Last updated:2025-04-18 09:52:21

APC4 Properties

Boiling point 652.326±65.00 °C(Press: 760.00 Torr)(predicted)
Density 1.334±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 17.174±0.30(predicted)

APC4 Chemical Properties, Uses, Production

Uses

AP-C4 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 5.2. AP-C3 does not inhibit cGKII-dependent anion secretion[1].

References

[1] Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181. DOI:10.1074/jbc.RA118.002835

APC4 Preparation Products And Raw materials

Raw materials

Preparation Products

APC4 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
TargetMol Chemicals Inc. 58
APC4 1H-Indole-3-ethanamine, N-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-pyrimidinyl]- 682794-85-0