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tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate

tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate Structure
tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate structure
CAS No.
198904-84-6
Chemical Name:
tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate
Synonyms
Atazanavir Impurity 40;tert-Butyl 2-(4-(pyridin-2-yl);Hydrazinecarboxylic acid, [[4-(2-;2-[[4-(2-Pyridinyl)phenyl]methylene]- hydrazin;Hydrazinecarboxylicacid,[[4-(2-pyridinyl)phenyl];N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone;pyridinyl)phenyl]methylene]-, 1,1-dimethylethyl ester;[[4-(2-pyridinyl)phenyl]methylene]-, 1,1-dimethylethyl ester;tert-Butyl 2-(4-(pyridin-2-yl)benzylidene)hydrazinecarboxylate;tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarbox...
CBNumber:
CB4547453
Molecular Formula:
C17H19N3O2
Molecular Weight:
297.35
MDL Number:
MOL File:
198904-84-6.mol
MSDS File:
SDS
Last updated:2026-05-28 05:13:14
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tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate Properties

Density 1.10±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Dichloromethane, Methanol
pka 10.14±0.46(Predicted)
form Solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 262950 N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone 198904-84-6 100mg $389 2026-06-03 Buy
Usbiological 262950 N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone 198904-84-6 250mg $576 2026-06-03 Buy
Usbiological 262950 N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone 198904-84-6 500mg $864 2026-06-03 Buy
Usbiological 262950 N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone 198904-84-6 1g $1310 2026-06-03 Buy
Usbiological 262950 N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone 198904-84-6 2g $2076 2026-06-03 Buy
Product number Packaging Price Buy
262950 100mg $389 Buy
262950 250mg $576 Buy
262950 500mg $864 Buy
262950 1g $1310 Buy
262950 2g $2076 Buy

tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate Chemical Properties, Uses, Production

Chemical Properties

White Solid

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate

198904-84-6

General procedure for the synthesis of tert-butyl [[4-(2-pyridinyl)phenyl]methylene]-hydrazine carboxylate from di-tert-butyl dicarbonate: 4-(pyridin-2-yl)benzaldehyde hydrazone (2.2 g, 12.0 mmol), THF (50 mL), and a 0.5 M aqueous sodium hydroxide solution (10 mL) were added to a 100 mL four-necked flask, followed by a 20-minute period at 30 °C under stirring. A solution of di-tert-butyl dicarbonate (5.2 g, 23.8 mmol) in THF (5 mL) was added dropwise. The reaction mixture was heated to 55-60 °C and stirred vigorously for 3 h at this temperature. The reaction progress was monitored by HPLC and the yield of N-(tert-butoxycarbonyl)-N'-[4-(pyridin-2-yl)phenylmethylene]hydrazine was confirmed to be 93.2%. After completion of the reaction, the mixture was concentrated under reduced pressure and the resulting crystalline residue was washed with a small amount of cold methanol and recrystallized from toluene to give purified N-(tert-butoxycarbonyl)-N'-[4-(pyridin-2-yl)phenylmethylene]hydrazine (yield 2.1 g). The product was characterized by the following data: melting point: 169.2-171.5 °C; IR (KBr, cm-1): 3308, 1712, 1612, 1586, 1528, 1510, 1468, 1434, 1394, 1360, 1310, 1246, 1158, 780; 1H-NMR (CDCl3, ppm) δ: 1.55 (s, 9H), 7.24 (m, 1H), 7.75 (m, 2H), 7.78 (d, 2H), 7.87 (s, 1H), 8.00 (d, 2H), 8.16 (s, 1H), 8.70 (m, 1H).

References

[1] Patent: US6147218, 2000, A

tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate Preparation Products And Raw materials

Raw materials

4-(2-Pyridinyl)benzaldehyde Di-tert-butyl dicarbonate tert-Butyl carbazate Sodium hydroxide Tetrahydrofuran

Preparation Products

Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir

tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate Suppliers

Global Suppliers ( 86)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Nanjing Vital Chemical Co., Ltd. Please Send Email 18652950785 chemweiao@163.com China 4368 65
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Shanghai Synchem Pharma Co., ltd 21-619849051-1 18521059765 synchempharma@aliyun.com China 4988 55
Roark Standards 0755-83552066 15986688328 service@roarkstandards.com China 1442 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9609 60
Capot Chemical Co.,Ltd. +86-（0）57185586718 +86-13336195806 sales@capot.com China 29626 60
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Nanjing Vital Chemical Co., Ltd. 65
Nanjing Norris-Pharm Technology Co., Ltd 55
Shanghai Synchem Pharma Co., ltd 55
Roark Standards 58
Amadis Chemical Company Limited 58
Shenzhen SUNGENING Bio-Medical Co., Ltd. 60
Capot Chemical Co.,Ltd. 60
Aikon International Limited 58

View Latest Price from tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate pictures 2026-09-02 tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate
198904-84-6
 $5.00 1KG 99% Henan Fengda Chemical Co., Ltd
tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate pictures 2025-12-24 tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate
198904-84-6
 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
Tert-butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate pictures 2023-06-19 Tert-butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate
198904-84-6
 1kg 98% Capot Chemical Co.,Ltd.

198904-84-6 (tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate) Related Search:

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tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate Hydrazinecarboxylic acid, [[4-(2-pyridinyl)phenyl]methylene]-, 1,1-dimethylethyl ester [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylic acid 1,1-dimethylethyl ester [[4-(2-pyridinyl)phenyl]methylene]-, 1,1-dimethylethyl ester Hydrazinecarboxylicacid,[[4-(2-pyridinyl)phenyl] N-1-Boc-N-2-[4-(2-pyridinyl)benzylidene]hydrazone Hydrazinecarboxylic acid, [[4-(2- pyridinyl)phenyl]methylene]-, 1,1-dimethylethyl ester N-[[4-(2-pyridinyl)phenyl]methylideneamino]carbamic acid tert-butyl ester Atazanavir Impurity 40 tert-Butyl [[4-(2-pyridinyl)phenyl]Methylene]hydrazinecarboxylatecas tert-Butyl 2-(4-(pyridin-2-yl)benzylidene)hydrazinecarboxylate (E)-tert-butyl 2-(4-(pyridin-2-yl)benzylidene)hydrazinecarboxylate tert-Butyl 2-(4-(pyridin-2-yl) 2-[[4-(2-Pyridinyl)phenyl]methylene]- hydrazin Hydrazinecarboxylic acid, 2-[[4-(2-pyridinyl)phenyl]methylene]-, 1,1-dimethylethyl ester tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarbox... 2-[[4-(2-Pyridinyl)phenyl]methylene]-hydrazinecarboxylic acid-1,1-dimethylethyl ester (BPBH) 198904-84-6 198904-86-4 Aromatics Compounds Aromatics Heterocycles