ELEUTHEROSIDE B1(RG)
- CAS No.
- 16845-16-2
- Chemical Name:
- ELEUTHEROSIDE B1(RG)
- Synonyms
- ELEUTHEROSIDE B1(RG);Eleutheroside B1, 10 mM in DMSO;2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-;2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-6,8-dimethoxy-;6,8-Dimethoxy-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one;Eleutheroside B 1,Influenza Virus,anti-inflammatory,virus,host,Eleutheroside B1,anti-influenza,Eleutheroside B-1,Inhibitor,genes,biosynthesis,inhibit
- CBNumber:
- CB4655037
- Molecular Formula:
- C17H20O10
- Molecular Weight:
- 384.34
- MDL Number:
- MOL File:
- 16845-16-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 675.0±55.0 °C(Predicted) |
|---|---|
| Density | 1.524±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, away from moisture and light |
| pka | 12.65±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | AZA7PP6D4R |
ELEUTHEROSIDE B1(RG) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | RAA84516 | Eleutheroside B1 | 16845-16-2 | 25mg | $895.5 | 2026-06-05 | Buy |
| Biosynth | RAA84516 | Eleutheroside B1 | 16845-16-2 | 50mg | $1433 | 2026-06-05 | Buy |
| Biosynth | RAA84516 | Eleutheroside B1 | 16845-16-2 | 100mg | $1994 | 2026-06-05 | Buy |
| ChemScene | CS-0113675 | Eleutheroside B1 99.00% | 16845-16-2 | 1mg | $271 | 2026-06-04 | Buy |
| ChemScene | CS-0113675 | Eleutheroside B1 99.00% | 16845-16-2 | 5mg | $596 | 2026-06-04 | Buy |
ELEUTHEROSIDE B1(RG) Chemical Properties, Uses, Production
Chemical Properties
White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus.
Uses
Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50value of 64-125μg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].
Biological Activity
Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity.
in vitro
Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.
RT-PCR
| Cell Line: | Virus-infected A549 cells |
| Concentration: | 100 μg/ml |
| Incubation Time: | 24 hours |
| Result: | The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased. |
References
[1] Yan W, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.Int J Mol Med.2018Nov;42(5):2776-2792. DOI:10.3892/ijmm.2018.3863
ELEUTHEROSIDE B1(RG) Preparation Products And Raw materials
Raw materials
Preparation Products
ELEUTHEROSIDE B1(RG) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Chengdu Herbpurify Co.Ltd. | 2355253622; 18981954830 | 2355253622@qq.com; | China | 1089 | 58 |
| Shanghai Yihe Biological Technology Co., Ltd. | 021-68882955 17721395025 | 2423903095@qq.com | China | 5000 | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
| Hefei Bomei Biotechnology Co., Ltd. | 13739298932 13856598764 | 531626407@qq.com | China | 5107 | 58 |
| Nanjing Yuanzhi Biotechnology Co. Ltd. | 15805159960; | 1211550495@qq.com | China | 1797 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3147 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2934 | 58 |
View Latest Price from ELEUTHEROSIDE B1(RG) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-
16845-16-2
|
$9.80 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- 2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-
16845-16-2
- $9.80
- ≥98%
- Career Henan Chemical Co
