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N-Acetyl-D-mannosamine

N-Acetyl-D-mannosamine structure

CAS No.: 7772-94-3

Chemical Name:: N-Acetyl-D-mannosamine

Synonyms: N-ACETYL-D-MANNOSAMINE MONOHYDRATE;2-(Acetylamino)-2-deoxy-β-D-mannopyranose;3515-17-6;N-((2R,3S,4R,5S,6R);N-Acetyl-D-mannosamine;N-Acetyl-β-D-mannosamine;N-Acetyl-D-mannosamine,98%;beta-D-N-Acetylmannosamine;Cyclic N-Acetyl-D-mannosamine;N-ACETYL-D-MANNOSAMINE HYDRATE

CBNumber:: CB4667317

Molecular Formula:: C8H15NO6

Molecular Weight:: 221.21

MDL Number:: MFCD00069808

MOL File:: 7772-94-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-11 08:51:26

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N-Acetyl-D-mannosamine Properties

Melting point	130°C (dec.)
Boiling point	595.4±50.0 °C(Predicted)
Density	1.50±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Methanol (Slightly), Water (Slightly)
pka	12.04±0.70(Predicted)
form	powder
color	White to Off-White
biological source	animal (crustaceans)
Water Solubility	water: 50mg/mL, clear, colorless to faintly yellow
BRN	1346524
Stability	Hygroscopic
InChI	1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5+,6-,7-,8+/m1/s1
InChIKey	MBLBDJOUHNCFQT-YWIQKCBGSA-N
SMILES	CC(=O)N[C@@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
CAS DataBase Reference	7772-94-3(CAS DataBase Reference)
FDA UNII	88J1ZMR63L
EPA Substance Registry System	.beta.-D-Mannopyranose, 2-(acetylamino)-2-deoxy- (7772-94-3)
UNSPSC Code	12352201
NACRES	NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280-P271

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25

WGK Germany

TSCA

TSCA listed

HS Code

29329985

Storage Class

11 - Combustible Solids

NFPA 704

	0
0		0

N-Acetyl-D-mannosamine price More Price(65)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHG0017	N-Acetyl-D-mannosamine	7772-94-3	10g	$321	2026-04-30	Buy
Sigma-Aldrich	PHG0017	N-Acetyl-D-mannosamine	7772-94-3	1kg	$17860	2026-04-30	Buy
Cayman Chemical	10011060	N-acetyl-D-Mannosamine ≥95%	7772-94-3	100mg	$13	2026-04-30	Buy
Cayman Chemical	10011060	N-acetyl-D-Mannosamine ≥95%	7772-94-3	250mg	$25	2026-04-30	Buy
Cayman Chemical	10011060	N-acetyl-D-Mannosamine ≥95%	7772-94-3	500mg	$44	2026-04-30	Buy

Product number	Packaging	Price	Buy
PHG0017	10g	$321	Buy
PHG0017	1kg	$17860	Buy
10011060	100mg	$13	Buy
10011060	250mg	$25	Buy
10011060	500mg	$44	Buy

N-Acetyl-D-mannosamine Chemical Properties, Uses, Production

Description

N-Acetyl-D-mannosamine is used as a substrate to identify, distinguish and characterise enzymes; it is also an effective glycan modulator that significantly reduces the proportion of high-mannose glycans in antibodies by promoting glycan maturation.
N-Acetyl-D-mannosamine(ManNAc) is primarily used in protein expression—particularly in the production of recombinant proteins such as therapeutic antibodies—to precisely regulate the glycosylation quality of the product, which is crucial for optimising the safety and efficacy of the drug. N-Acetyl-D-mannosamine (ManNAc) is a direct precursor of sialic acid (Neu5Ac) and can be converted into Neu5Ac via enzymatic reactions, playing a vital role in the glycan chains on the cell surface. As an effective glycan modifier, it significantly reduces the proportion of high-mannose-type glycans in antibodies by promoting glycan maturation.

Chemical Properties

Off-White Solid

Uses

A derivative of D-Mannosamine (M167000).

Definition

ChEBI: N-acetyl-D-mannosamine is an N-acetylmannosamine having D-configuration. It has a role as a bacterial metabolite. It is a N-acyl-D-mannosamine, a N-acetyl-D-hexosamine and a N-acetylmannosamine.

Biological Activity

N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of polysialic acid. Transport studies in the E. coli K1 strain have been performed to probe the effect of ManNAc on capsular polysialic acid production.

IC 50

Microbial Metabolite; Human Endogenous Metabolite

N-Acetyl-D-mannosamine Preparation Products And Raw materials

Raw materials

Preparation Products

N-Acetyl-D-mannosamine Suppliers

Global Suppliers ( 299)

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Zhengshuo Biological Technology Co., Ltd	13665754639	wulicheng2@126.com	China	21	58
Ning Bo hongxiang bio-chem Co.,Ltd.	574-66003444 13071918355	hongyubiochem@aliyun.com	China	9	60
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd	0512-66317708 13372112871	huijuan@zitrans.cn	China	1280	58
Hubei Chenghai Chemical Co., Ltd	027-59220433 18327245847	1400838877@qq.com	China	9527	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64

Supplier	Advantage
Zhejiang Zhengshuo Biological Technology Co., Ltd	58
Ning Bo hongxiang bio-chem Co.,Ltd.	60
Z-trans Biochemistry Technology (Suzhou) Co.,Ltd	58
Hubei Chenghai Chemical Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Alfa Aesar	84
Energy Chemical	61
Adamas Reagent, Ltd.	59
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64

View Latest Price from N-Acetyl-D-mannosamine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	N-Acetyl-D-mannosamine 7772-94-3		10G	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-08-22	N-Acetyl-D-mannosamine 3615-17-6			99.84%	10g	TargetMol Chemicals Inc.
2025-04-15	N-Acetyl-D-mannosamine 7772-94-3	$32.00	1kg	99%	5000kg/week	Hebei Zhuanglai Chemical Trading Co.,Ltd

N-Acetyl-D-mannosamine
7772-94-3
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

N-Acetyl-D-mannosamine
3615-17-6
$0.00
99.84%
TargetMol Chemicals Inc.

N-Acetyl-D-mannosamine
7772-94-3
$32.00
99%
Hebei Zhuanglai Chemical Trading Co.,Ltd

N-Acetyl-D-mannosamine Spectrum

N-Acetyl-D-mannosamine(7772-94-3)¹HNMR

7772-94-3 (N-Acetyl-D-mannosamine) Related Search:

TATM Acetyl chloride Acetazolamide D-Mannitol Acetylacetone

Tetraacetylethylenediamine 2-Acetamido-2-deoxy-D-mannopyranose D-Mannose 2-acetamido-2-deoxy-D-mannose D-Mannosamine

mannosamine ManNaz 2-Acetamido-2-deoxy-D-mannono-1,4-lactone N-Acetyl-D-mannosamine-6-3H N-Acetyl L-mannosamine

N-Acetyl-D-mannosamine Acetyl-D-mannosamine, N-(P) N-Acetyl-D-mannosamine-2-h(3)

1of4

2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE N-ACETYL-D-MANNOSAMINE HYDRATE 2-(acetylamino)-2-deoxy-beta-d-mannopyranos N-Acetyl-D-mannosamine(ManNAc) 2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE, N-ACETYL-D-MANNOSAMINE HYDRATE N-Acetyl-D-mannosamine N-Acetyl-D-mannosamine,98% 2-ACETAMIDO-2-DEOXY-D-MANNOPYRANOSE HYDRATE, N-ACETYL-D-MANNOSAMINE HY 2-(Acetylamino)-2-deoxy-beta-D-mannopyranose 2-Acetamido-2-deoxy-D-mannose monohydrate N-((2R,3S,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-3-yl)acetaMide (2S,3S,4R,5R)-N-acetyl-2,3,4,5,6-pentahydroxyhexanamide 2-(Acetamido)-2-deoxy-beta-D-mannopyranose98% 2-(Acetamido)-2-deoxy-beta-D-mannopyranose 98% N-Acetyl-beta-D-mannosamine, N-[(2R,3S,4R,5S,6R)-6-(Hydroxymethyl)tetrahydro-2,4,5-trihydroxy-2H-pyran-3-yl]acetamide N-((2S,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl)acetaMide hydrate -2,4,5-Trihydroxy-6-(hydroxymethyl) N-((2R,3S,4R,5S,6R) 3515-17-6 β-D-Mannopyranose, 2-(acetylamino)-2-deoxy- N-Acetyl-D-mannosamine USP/EP/BP Cyclic N-Acetyl-D-mannosamine N-Acetyl-D-mannosamine (Cyclic ManNAc) High purity CAS 7772-94-3 N-Acetyl-D-mannosamine in stock N-Acetyl-D-mannosamine x H2O (2-Acetamido-2-deoxy-D-mannose monohydrate, D-ManAc x H2O) N-Acetyl-β-D-mannosamine beta-D-N-Acetylmannosamine N-Acetyl-D-mannosamine 2-(Acetamido)-2-deoxy-beta-D-mannopyranose 2-(Acetcarboxcarboxcarboxamido)-2-deoxy-beta-D-mannopyranose 2-(Acetylamino)-2-deoxy-β-D-mannopyranose N-ACETYL-D-MANNOSAMINE MONOHYDRATE N-[(2R,3S,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide 7772-94-3 3515-17-6 C8H15NO6H2O Metabolomics Metabolites and Cofactors on the Metabolic Pathways Chart Metabolic Pathways Carbohydrate BioChemical 13C & 2H Sugars Carbohydrates & Derivatives Carbohydrate Metabolic Pathways Metabolites and Cofactors on the Metabolic Pathways Chart Carbohydrates Bioproducts Sugar derivatives Glycon Biochem