Boc-Ala-Ala-OH
- CAS No.
- 27317-69-7
- Chemical Name:
- Boc-Ala-Ala-OH
- Synonyms
- Boc-Ala-Ala;(tert-Butoxycarbonyl)-L-alanyl-L-alanine;Boc-AA-OH;Boc-Ala-Ala-OH;Boc-L-Ala-L-Ala-OH;BOC-ALA-ALA-OH H2O;BOC-L-ALANYL-L-ALANINE H2O;BOC-L-ALANYL-L-ALANINE MONOHYDRATE;N-tert-Butoxycarbonyl-L-alanyl-L-alanine;L-Alanine,N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-
- CBNumber:
- CB4673170
- Molecular Formula:
- C11H20N2O5
- Molecular Weight:
- 260.29
- MDL Number:
- MFCD00038564
- MOL File:
- 27317-69-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 132-133 °C |
|---|---|
| Boiling point | 483.5±30.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.52±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChI | 1S/C11H20N2O5/c1-6(8(14)12-7(2)9(15)16)13-10(17)18-11(3,4)5/h6-7H,1-5H3,(H,12,14)(H,13,17)(H,15,16)/t6-,7-/m0/s1 |
| InChIKey | BZNDDHWTEVCBAD-BQBZGAKWSA-N |
| SMILES | C[C@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(O)=O |
| UNSPSC Code | 12352209 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| REACH Registrations | Active |
Boc-Ala-Ala-OH price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6187 | (tert-Butoxycarbonyl)-L-alanyl-L-alanine | 27317-69-7 | 1G | $42 | 2026-04-30 | Buy |
| TCI Chemical | B6187 | (tert-Butoxycarbonyl)-L-alanyl-L-alanine | 27317-69-7 | 5G | $124 | 2026-04-30 | Buy |
| Usbiological | 264954 | Boc-Ala-Ala-OH Asreported | 27317-69-7 | 2g | $375 | 2026-06-03 | Buy |
| Usbiological | 264954 | Boc-Ala-Ala-OH Asreported | 27317-69-7 | 5g | $608 | 2026-06-03 | Buy |
| Usbiological | 264954 | Boc-Ala-Ala-OH Asreported | 27317-69-7 | 10g | $852 | 2026-06-03 | Buy |
Boc-Ala-Ala-OH Chemical Properties,Uses,Production
Uses
N-Phthalyl-alanine is used in the preparation of endothiopeptide inhibitors of HIV-1 Protease.
Synthesis
1948-31-8
24424-99-5
27317-69-7
GENERAL STEPS: L-alanyl-L-alanine (1 mmol) was slowly added to a solution of ethanol (1 mL) containing guanidine hydrochloride (15 mmol) and di-tert-butyl dicarbonate (2.5-3 mmol) under stirring conditions, maintaining the reaction temperature at 35-40°C. The reaction mixture was stirred continuously until a clarified solution was formed. Subsequently, the ethanol was removed by evaporation under reduced pressure. The residue was washed sequentially with distilled water (2 mL) and hexane or petroleum ether (2 mL) to obtain nearly pure N-tert-butoxycarbonyl-alanylalanine. If further product purity is required, the crude product can be purified by recrystallization.
References
[1] Journal of Organic Chemistry, 2007, vol. 72, # 2, p. 525 - 531
[2] Journal of the American Chemical Society, 2000, vol. 122, # 12, p. 2687 - 2697
[3] Journal of Organic Chemistry, 1994, vol. 59, # 19, p. 5784 - 5793
[4] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1260 - 1264
[5] Journal of Medicinal Chemistry, 2005, vol. 48, # 16, p. 5305 - 5320
Boc-Ala-Ala-OH Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sichuan Ampebiochem Co., Ltd. | 028-65294243 18682730901 | sales@ampebiochem.com | China | 1000 | 58 |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6959 | 55 |
| NINGBO INNO PHARMCHEM CO.,LTD. | 86-574-27787657 | info@dearchem.com | China | 4607 | 58 |
| Shanghai GL Peptide Ltd. | +86-21-61263310 13764994101 | fisherwang@glschina.com | China | 8058 | 55 |
View Lastest Price from Boc-Ala-Ala-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Boc-Ala-Ala-OH
27317-69-7
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2025-04-04 | BOC-ALA-ALA-OH
27317-69-7
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Boc-Ala-Ala-OH
27317-69-7
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- BOC-ALA-ALA-OH
27317-69-7
- 98%
- Henan Aochuang Chemical Co.,Ltd.
