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BOC-VAL-PRO-OH

BOC-VAL-PRO-OH Structure
BOC-VAL-PRO-OH structure
CAS No.
23361-28-6
Chemical Name:
BOC-VAL-PRO-OH
Synonyms
Boc-Val-Pro;Boc-Val-L-Pro;BOC-VAL-PRO-OH;-3-methylbutanoyl);Boc-L-Val-L-Pro-OH;BOC-L-VALYL PROLINE;N-BOC-L-VALYL-L-PROLINE;(Tert-Butoxy)Carbonyl Val-Pro-OH;N-tert-Butoxycarbonyl-L-valyl-L-proline;N-(tert-butyloxycarbonyl)-L-valyl-L-proline
CBNumber:
CB7177422
Molecular Formula:
C15H26N2O5
Molecular Weight:
314.38
MDL Number:
MFCD00076997
MOL File:
23361-28-6.mol
Last updated:2025-07-24 18:13:43
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BOC-VAL-PRO-OH Properties

Melting point 137-138 °C
Boiling point 503.2±45.0 °C(Predicted)
Density 1.171±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
pka 3.50±0.20(Predicted)
form Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

BOC-VAL-PRO-OH price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B663298 BOC-VAL-PRO-OH 23361-28-6 10mg $45 2021-12-16 Buy
Usbiological 236722 Boc-Val-Pro-OH 23361-28-6 250mg $184 2021-12-16 Buy
Usbiological 264996 Boc-Val-Pro-OH 23361-28-6 500mg $333 2021-12-16 Buy
Biosynth Carbosynth FB48372 Boc-Val-Pro-OH 23361-28-6 1g $111.4 2021-12-16 Buy
American Custom Chemicals Corporation AAA0002202 BOC-VAL-PRO-OH 95.00% 23361-28-6 250MG $141.75 2021-12-16 Buy
Product number Packaging Price Buy
B663298 10mg $45 Buy
236722 250mg $184 Buy
264996 500mg $333 Buy
FB48372 1g $111.4 Buy
AAA0002202 250MG $141.75 Buy

BOC-VAL-PRO-OH Chemical Properties,Uses,Production

Uses

Boc-Val-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-, methyl ester

38017-75-3

BOC-VAL-PRO-OH

23361-28-6

N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-L-proline (Compound 2) was prepared from compound (CAS: 38017-75-3) by alkali hydrolysis reaction using a modified literature method. The procedure was as follows: compound 1 (1.372 g, 4.18 mmol) was dissolved in a solvent mixture of tetrahydrofuran (THF) and water (3:1 volume ratio, total volume of 80 mL, wherein 60 mL of THF and 20 mL of water). Subsequently, lithium hydroxide monohydrate (LiOH-H2O, 0.878 g, 20.89 mmol) was added and the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was acidified with 0.5 M hydrochloric acid (50 mL) to quench the reaction, followed by extraction with ethyl acetate (EtOAc, 4 × 60 mL). The organic phases were combined, washed with saturated saline (1 × 100 mL) and dried over anhydrous magnesium sulfate (MgSO4). The solvent was removed by evaporation under reduced pressure to give a white solid product (1.186 g, 90% yield). The structure of the product was confirmed by 1H NMR, 13C NMR and ESI-MS: 1H NMR (400 MHz, CDCl3) δ 9.37 (br s, 1H, COOH), 5.46 (d, J = 9.4 Hz, 1H, NH), 4.55 (dd, J = 8.1, 4.8 Hz, 1H, Pro-αH), 4.26 (dd, J = 9.4, 6.4, 6.4, 6.4), 1H, Pro-αH), 1H, Pro-αH, 1H, Pro-αH), 1H, Pro-αH, Pro-αH, Pro-αH, Pro-αH. J = 9.4, 6.8 Hz, 1H, Val-αH), 3.83-3.59 (m, 2H, Pro-δH), 2.25-1.86 (m, 5H, Pro-βH, Pro-γH, Val-βH), 1.40 (s, 9H, tBu), 0.98 (d, J = 6.7 Hz, 3H, Val-γH), 0.91 (d , J = 6.7 Hz, 3H, Val-γH); 13C NMR (101 MHz, CDCl3) δ 174.5, 172.4, 155.9, 79.6, 59.1, 57.0, 47.5, 31.2, 28.5, 28.3, 24.8, 19.2, 17.6; ESI-MS (m/z): [M+Na]+ calculated for C15H26N2NaO5 337.1739, found 337.1734.

References

[1] Tetrahedron, 2018, vol. 74, # 12, p. 1184 - 1190
[2] Journal of Organic Chemistry, 2003, vol. 68, # 12, p. 5006 - 5008
[3] Recueil: Journal of the Royal Netherlands Chemical Society, 1980, vol. 99, # 4, p. 124 - 130
[4] Polish Journal of Chemistry, 1988, vol. 62, # 4-6, p. 457 - 464
[5] Bollettino Chimico Farmaceutico, 1999, vol. 138, # 4, p. 160 - 164

BOC-VAL-PRO-OH Preparation Products And Raw materials

Raw materials

N-Boc-L-valine L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-, methyl ester L-Proline Lithium hydroxide monohydrate Tetrahydrofuran

Preparation Products

BOC-VAL-PRO-OH Suppliers

Global( 97)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		+8617390183901 cynthia@enlaibio.com China 1100 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29734 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29800 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Finetech Industry Limited 		+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9629 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Supplier Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
GL Biochem(Binhai) Ltd. 		58
Finetech Industry Limited 		58
Nextpeptide Inc 		58
Labnetwork lnc. 		58

View Lastest Price from BOC-VAL-PRO-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Val-Pro-OH pictures 2025-09-24 Boc-Val-Pro-OH
23361-28-6
 US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
BOC-VAL-PRO-OH pictures 2025-09-17 BOC-VAL-PRO-OH
23361-28-6
 US $1590.00-1400.00 / kilograms 1kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
BOC-VAL-PRO-OH pictures 2019-12-27 BOC-VAL-PRO-OH
23361-28-6
 US $6.60 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
  • Boc-Val-Pro-OH pictures
  • Boc-Val-Pro-OH
    23361-28-6
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
  • BOC-VAL-PRO-OH pictures
  • BOC-VAL-PRO-OH
    23361-28-6
  • US $1590.00-1400.00 / kilograms
  • 99%
  • Hebei Dangtong Import and export Co LTD

23361-28-6(BOC-VAL-PRO-OH)Related Search:

BOC-VAL-GLY-OH BOC-GLY-PRO-OH BOC-ALA-ALA-OH N-(tert-Butoxycarbonyl)glycylglycine BOC-ILE-PRO-OME
CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER BOC-VAL-PRO-OH (S)-2-N-BOC-AMINO-1-PYRROLIDIN-1-YL-PROPAN-1-ONE BOC-ALA-GLY-OH DIETHYLCARBAMOYLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER
TERT-BUTYL 2-(BUTYLAMINO)ETHYLCARBAMATE (S)-1-N-BOC-2-METHYL-1-PYRROLIDIN-1-YLMETHYL-PROPYLAMINE tert-butyl N-[2-(dimethylamino)-2-oxoethyl]carbamate H-VAL-PRO-OH HCL BOC-ALA-PRO-OH
BOC-VAL-NH2

1of4

BOC-L-VALYL PROLINE BOC-VAL-PRO-OH Boc-L-Val-L-Pro-OH -3-methylbutanoyl) (S)-1-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylic acid (Tert-Butoxy)Carbonyl Val-Pro-OH N-tert-Butoxycarbonyl-L-valyl-L-proline Boc-Val-Pro L-Proline, N-[(1,1-diMethylethoxy)carbonyl]-L-valyl- N-BOC-L-VALYL-L-PROLINE (2S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanoyl]pyrrolidine-2-carboxylic acid N-(tert-butyloxycarbonyl)-L-valyl-L-proline N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-L-proline (2S)-1-[(2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoyl]pyrrolidine-2-carboxylic acid Boc-Val-L-Pro 23361-28-6 C15H26N2O5