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Boc-Val-Pro-OH

Boc-Val-Pro-OH Structure
Boc-Val-Pro-OH structure
CAS No.
23361-28-6
Chemical Name:
Boc-Val-Pro-OH
Synonyms
Boc-Val-Pro;Boc-Val-L-Pro;Boc-Val-Pro-OH;-3-methylbutanoyl);Boc-L-Val-L-Pro-OH;BOC-L-VALYL PROLINE;N-BOC-L-VALYL-L-PROLINE;(Tert-Butoxy)Carbonyl Val-Pro-OH;N-tert-Butoxycarbonyl-L-valyl-L-proline;N-(tert-butyloxycarbonyl)-L-valyl-L-proline
CBNumber:
CB7177422
Molecular Formula:
C15H26N2O5
Molecular Weight:
314.38
MDL Number:
MFCD00076997
MOL File:
23361-28-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:43
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Boc-Val-Pro-OH Properties

Melting point 137-138 °C
Boiling point 503.2±45.0 °C(Predicted)
Density 1.171±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
pka 3.50±0.20(Predicted)
form Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Boc-Val-Pro-OH price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264996 Boc-Val-Pro-OH Asreported 23361-28-6 500mg $333 2026-06-03 Buy
Usbiological 264996 Boc-Val-Pro-OH Asreported 23361-28-6 1g $476 2026-06-03 Buy
Usbiological 264996 Boc-Val-Pro-OH Asreported 23361-28-6 2g $642 2026-06-03 Buy
Usbiological 264996 Boc-Val-Pro-OH Asreported 23361-28-6 5g $1020 2026-06-03 Buy
Usbiological 264996 Boc-Val-Pro-OH Asreported 23361-28-6 10g $1426 2026-06-03 Buy
Product number Packaging Price Buy
264996 500mg $333 Buy
264996 1g $476 Buy
264996 2g $642 Buy
264996 5g $1020 Buy
264996 10g $1426 Buy

Boc-Val-Pro-OH Chemical Properties, Uses, Production

Uses

Boc-Val-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-, methyl ester

38017-75-3

BOC-VAL-PRO-OH

23361-28-6

N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-L-proline (Compound 2) was prepared from compound (CAS: 38017-75-3) by alkali hydrolysis reaction using a modified literature method. The procedure was as follows: compound 1 (1.372 g, 4.18 mmol) was dissolved in a solvent mixture of tetrahydrofuran (THF) and water (3:1 volume ratio, total volume of 80 mL, wherein 60 mL of THF and 20 mL of water). Subsequently, lithium hydroxide monohydrate (LiOH-H2O, 0.878 g, 20.89 mmol) was added and the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was acidified with 0.5 M hydrochloric acid (50 mL) to quench the reaction, followed by extraction with ethyl acetate (EtOAc, 4 × 60 mL). The organic phases were combined, washed with saturated saline (1 × 100 mL) and dried over anhydrous magnesium sulfate (MgSO4). The solvent was removed by evaporation under reduced pressure to give a white solid product (1.186 g, 90% yield). The structure of the product was confirmed by 1H NMR, 13C NMR and ESI-MS: 1H NMR (400 MHz, CDCl3) δ 9.37 (br s, 1H, COOH), 5.46 (d, J = 9.4 Hz, 1H, NH), 4.55 (dd, J = 8.1, 4.8 Hz, 1H, Pro-αH), 4.26 (dd, J = 9.4, 6.4, 6.4, 6.4), 1H, Pro-αH), 1H, Pro-αH, 1H, Pro-αH), 1H, Pro-αH, Pro-αH, Pro-αH, Pro-αH. J = 9.4, 6.8 Hz, 1H, Val-αH), 3.83-3.59 (m, 2H, Pro-δH), 2.25-1.86 (m, 5H, Pro-βH, Pro-γH, Val-βH), 1.40 (s, 9H, tBu), 0.98 (d, J = 6.7 Hz, 3H, Val-γH), 0.91 (d , J = 6.7 Hz, 3H, Val-γH); 13C NMR (101 MHz, CDCl3) δ 174.5, 172.4, 155.9, 79.6, 59.1, 57.0, 47.5, 31.2, 28.5, 28.3, 24.8, 19.2, 17.6; ESI-MS (m/z): [M+Na]+ calculated for C15H26N2NaO5 337.1739, found 337.1734.

References

[1] Tetrahedron, 2018, vol. 74, # 12, p. 1184 - 1190
[2] Journal of Organic Chemistry, 2003, vol. 68, # 12, p. 5006 - 5008
[3] Recueil: Journal of the Royal Netherlands Chemical Society, 1980, vol. 99, # 4, p. 124 - 130
[4] Polish Journal of Chemistry, 1988, vol. 62, # 4-6, p. 457 - 464
[5] Bollettino Chimico Farmaceutico, 1999, vol. 138, # 4, p. 160 - 164

Boc-Val-Pro-OH Preparation Products And Raw materials

Raw materials

N-Boc-L-valine L-Proline, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-, methyl ester L-Proline Lithium hydroxide monohydrate Tetrahydrofuran

Preparation Products

Boc-Val-Pro-OH Suppliers

Global Suppliers ( 99)
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Supplier Advantage
Capot Chemical Co., Ltd 66
Jia Xing Isenchem Co.,Ltd 66
Chemsky (shanghai) International Co.,Ltd 60
Shandong Xiya Chemical Co., Ltd 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai Sphchem Co., Ltd. 55
Hangzhou Sage Chemical Co., Ltd. 58
9ding chemical ( Shanghai) Limited 56
Bide Pharmatech Ltd. 60
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58

View Latest Price from Boc-Val-Pro-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Val-Pro-OH pictures 2026-09-15 Boc-Val-Pro-OH
23361-28-6
 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
BOC-VAL-PRO-OH pictures 2026-08-21 BOC-VAL-PRO-OH
23361-28-6
 $1400.00-1590.00 1kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
BOC-VAL-PRO-OH pictures 2019-12-27 BOC-VAL-PRO-OH
23361-28-6
 $6.60 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
  • BOC-VAL-PRO-OH pictures
  • BOC-VAL-PRO-OH
    23361-28-6
  • $1400.00-1590.00
  • 99%
  • Hebei Dangtong Import and export Co LTD

23361-28-6 (Boc-Val-Pro-OH) Related Search:

(S)-1-N-Boc-2-methyl-1-pyrrolidin-1-ylmethyl-propylamine Diethylcarbamoylmethyl-carbamic acid tert-butyl ester Boc-Val-Pro-OH Boc-Val-Gly-OH Carbamic acid, [2-(dimethylamino)ethyl]-, 1,1-dimethylethyl ester
Boc-Ala-Gly-OH Boc-Ala-Ala-OH Boc-Ala-Pro-OH H-Val-Pro-OH HCl tert-Butyl 2-(butylamino)ethylcarbamate
(S)-2-N-Boc-amino-1-pyrrolidin-1-yl-propan-1-one Boc-Ile-Pro-OMe Boc-Val-NH2 Boc-Gly-Pro-OH N-(tert-Butoxycarbonyl)glycylglycine
tert-butyl N-[2-(dimethylamino)-2-oxoethyl]carbamate

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BOC-L-VALYL PROLINE Boc-L-Val-L-Pro-OH -3-methylbutanoyl) (S)-1-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylic acid (Tert-Butoxy)Carbonyl Val-Pro-OH N-tert-Butoxycarbonyl-L-valyl-L-proline Boc-Val-Pro L-Proline, N-[(1,1-diMethylethoxy)carbonyl]-L-valyl- N-BOC-L-VALYL-L-PROLINE (2S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanoyl]pyrrolidine-2-carboxylic acid N-(tert-butyloxycarbonyl)-L-valyl-L-proline N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-L-proline (2S)-1-[(2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoyl]pyrrolidine-2-carboxylic acid Boc-Val-L-Pro Boc-Val-Pro-OH 23361-28-6 C15H26N2O5