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2,2-Difluoroethyl trifluoromethanesulfonate

CAS No.
74427-22-8
Chemical Name:
2,2-Difluoroethyl trifluoromethanesulfonate
Synonyms
2,2-DIFLUOROETHYL TRIFLATE;DK883;DKSI046;DKFELEX0235;Difluoroethyl triflate;2,2-Difluoro-ethyl 1,1,1- triflate;2-DIFLUOROETHYL TRIFLUOROMETHANESULFONATE;2,2-Difluoroethyl trifluoromethanesulfonate;2,2-DIFLUOROETHYL TRIFLUOROMETHANESULPHONATE;2,2-Difluoroethyltrifluoromethanesulphonate98%
CBNumber:
CB4679804
Molecular Formula:
C3H3F5O3S
Molecular Weight:
214.11
MDL Number:
MFCD02093342
MOL File:
74427-22-8.mol
Last updated:2026-09-12 18:52:56

2,2-Difluoroethyl trifluoromethanesulfonate Properties

Boiling point 118-120°C
Density 1.6150
refractive index 1.3300-1.3340
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form clear liquid
color Colorless to Light yellow
InChI InChI=1S/C3H3F5O3S/c4-2(5)1-11-12(9,10)3(6,7)8/h2H,1H2
InChIKey NKULBUOBGILEAR-UHFFFAOYSA-N
SMILES C(F)(F)(F)S(OCC(F)F)(=O)=O
EPA Substance Registry System 2,2-Difluoroethyl triflate (74427-22-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Corrosion (GHS05)
GHS02,GHS05
Signal word  Danger
Hazard statements  H226-H290-H314
Precautionary statements  P210-P233-P234-P240-P241+P242+P243-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P390-P403+P235-P405-P406-P501
Hazard Codes  T,Xi
Risk Statements  20/21/22-36/37/38-23/24/25
Safety Statements  23-26-36-63-45-36/37/39
RIDADR  2810
Hazard Note  Toxic
HazardClass  IRRITANT-HARMFUL
PackingGroup  II
HS Code  29159000
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
3 0

2,2-Difluoroethyl trifluoromethanesulfonate price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D5299 2,2-Difluoroethyl Trifluoromethanesulfonate >98.0%(GC) 74427-22-8 1g $41 2026-04-30 Buy
TCI Chemical D5299 2,2-Difluoroethyl Trifluoromethanesulfonate >98.0%(GC) 74427-22-8 5g $121 2026-04-30 Buy
Apolloscientific PC3793 2,2-Difluoroethyl trifluoromethanesulphonate 97% 74427-22-8 1g $21 2026-06-04 Buy
Apolloscientific PC3793 2,2-Difluoroethyl trifluoromethanesulphonate 97% 74427-22-8 5g $24 2026-06-04 Buy
Apolloscientific PC3793 2,2-Difluoroethyl trifluoromethanesulphonate 97% 74427-22-8 25g $66 2026-06-04 Buy
Product number Packaging Price Buy
D5299 1g $41 Buy
D5299 5g $121 Buy
PC3793 1g $21 Buy
PC3793 5g $24 Buy
PC3793 25g $66 Buy

2,2-Difluoroethyl trifluoromethanesulfonate Chemical Properties, Uses, Production

Uses

2,2-Difluoroethyl Triflate is used to prepare kinesin spindle protein inhibitors for treatment of taxane-refractory cancer. It is also used to synthesize MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa.

2,2-Difluoroethyl trifluoromethanesulfonate Preparation Products And Raw materials

Global Suppliers ( 206)
Supplier Tel Email Country ProdList Advantage
Hechi Zhuangming Biopharmaceutical Co., Ltd 18116363706 lvqiong@zmsilane.com China 100 58
Chongqing Xingcan Pharmaceutical Technology Co., Ltd. 13594048950 19923294409 xingcanyaoye@sina.com China 1590 58
SHANG FLUORO 021-65170832 15601903708 qinba_1@163.com China 401 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66

View Latest Price from 2,2-Difluoroethyl trifluoromethanesulfonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2-Difluoroethyl trifluoromethanesulfonate pictures 2026-08-25 2,2-Difluoroethyl trifluoromethanesulfonate
74427-22-8
$3.00-9.00 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2,2-DIFLUOROETHYL TRIFLUOROMETHANESULFONATE pictures 2026-06-30 2,2-DIFLUOROETHYL TRIFLUOROMETHANESULFONATE
74427-22-8
1KG 95.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2,2-Difluoroethyl trifluoromethanesulfonate pictures 2025-04-04 2,2-Difluoroethyl trifluoromethanesulfonate
74427-22-8
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2,2-DIFLUOROETHYL TRIFLUOROMETHANESULPHONATE 2,2-Difluoroethyl trifluoromethanesulphonate 98% 2,2-Difluoroethyltrifluoromethanesulphonate98% Trifluoromethanesulfonic acid 2,2-difluoroethyl ester Methanesulfonic acid, 1,1,1-trifluoro-, 2,2-difluoroethyl ester 1,1,1-Trifluoro-2,2-difluoroethyl Ester Methanesulfonic Acid 2-DIFLUOROETHYL TRIFLUOROMETHANESULFONATE Difluoroethyl triflate 2,2-Difluoroethyl 1,1,1-trifluoromethanesulfonate DK883 2,2-Difluoro-ethyl 1,1,1- triflate DKFELEX0235 DKSI046 2,2-difluoroethyl trifluoromethanesulfonate - [D87361] 2,2-DIFLUOROETHYL TRIFLATE 2,2-Difluoroethyl trifluoromethanesulfonate 74427-22-8 C3H3F5O3S