1-Indanone-6-carboxylic acid
- CAS No.
- 60031-08-5
- Chemical Name:
- 1-Indanone-6-carboxylic acid
- Synonyms
- 3-oxo-2,3-dihydro-1H-indene-5-carboxylic acid;6-CARBOXY-1-INDANONE;6-CARBOXYLIC ACID 1-INDANONE;1-INDANONE-6-CARBOXYLIC ACID;3-OXOINDANE-5-CARBOXYLIC ACID;3-OXO-INDAN-5-CARBOXYLIC ACID;3-oxo-1,2-dihydroindene-5-carboxylic Acid;2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBOXYLIC ACID;1H-Indene-5-carboxylic acid, 2,3-dihydro-3-oxo-;JR-8361, 2,3-Dihydro-3-oxo-1H-indene-5-carboxylic acid, 97%
- CBNumber:
- CB4684307
- Molecular Formula:
- C10H8O3
- Molecular Weight:
- 176.17
- MDL Number:
- MFCD02179295
- MOL File:
- 60031-08-5.mol
- MSDS File:
- SDS
| Melting point | 256-260 °C |
|---|---|
| Boiling point | 375.2±31.0 °C(Predicted) |
| Density | 1.381±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.99±0.20(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 60031-08-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 2918300090 |
1-Indanone-6-carboxylic acid price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR30552 | 3-Oxoindane-5-carboxylic acid 97% | 60031-08-5 | 250mg | $116 | 2026-06-04 | Buy |
| Matrix Scientific | 293703 | 3-Oxo-2,3-dihydro-1H-indene-5-carboxylic acid | 60031-08-5 | 250.00mg | $60 | 2026-05-19 | Buy |
| Matrix Scientific | 293703 | 3-Oxo-2,3-dihydro-1H-indene-5-carboxylic acid | 60031-08-5 | 1.00g | $138 | 2026-05-19 | Buy |
| Matrix Scientific | 293703 | 3-Oxo-2,3-dihydro-1H-indene-5-carboxylic acid | 60031-08-5 | 5.00g | $578 | 2026-05-19 | Buy |
| Synthonix | X53810 | 3-Oxo-2,3-dihydro-1H-indene-5-carboxylic acid 97% | 60031-08-5 | 100mg | $47 | 2026-05-06 | Buy |
1-Indanone-6-carboxylic acid Chemical Properties,Uses,Production
Synthesis
38628-51-2
60031-08-5
The general procedure for the synthesis of 1-indanone-6-carboxylic acid from 4-(2-carboxyethyl)benzoic acid is as follows: 6-carboxy-1-indanone, which is the feedstock of Example 206, was prepared as follows: 3-(4-carboxyphenyl)propionic acid (5 g, 0.026 mol), fresh AlCl3 (25 g, 7.2 equivalents, 0.187 mol) and NaCl (2.5 g , 10% of the mass of AlCl3) were added to a 100 mL flask equipped with a condenser and an internal thermometer. The flask was shaken briefly to mix the solids well and subsequently heated in an oil bath set at 190°C. The reaction was maintained at an internal temperature of 180°C or above for 1 hour (the mixture melted to a dark brown liquid during the reaction). After the reaction was complete, the mixture was cooled and poured into a 2000 mL beaker containing ice and washed with water. 180mL of 6M HCl and 250mL of EtOAc were added and the layers were separated. The aqueous layer was extracted with EtOAc (3 x 200mL). The organic layers were combined, washed sequentially with 2M HCl, water and brine, dried with MgSO4, filtered and concentrated in vacuum to give a light brown solid 6-carboxy-1-indanone (4.10 g, 90% yield), which was used directly in the next synthesis.
References
[1] Patent: WO2005/87236, 2005, A1. Location in patent: Page/Page column 39
[2] Patent: US2010/249095, 2010, A1. Location in patent: Page/Page column 68-69
[3] Tetrahedron, 1995, vol. 51, # 1, p. 203 - 216
[4] Journal of the Chemical Society, 1956, p. 4647,3652
[5] Patent: US2012/71461, 2012, A1. Location in patent: Page/Page column 60
1-Indanone-6-carboxylic acid Preparation Products And Raw materials
1-Indanone-6-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Acesys Pharmatech | 18860950986 | tangmanman@zenjipharma.com | China | 1731 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. | +86-28-85122536 85324413 | market@astatech.cn | China | 8016 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| NINGBO INNO PHARMCHEM CO.,LTD. | 86-574-27787657 | info@dearchem.com | China | 4607 | 58 |
| Shanghai YuLue Chemical Co., Ltd. | 021-60345187 13671753212 | lzz841106@aliyun.com | China | 10244 | 55 |
| LABTER PHARMATECH(BEIJING) CO.,LTD | 010-56330744 18310155299 | sales@labter.com.cn | China | 19999 | 55 |
View Lastest Price from 1-Indanone-6-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | 1-Indanone-6-carboxylic acid
60031-08-5
|
$1.00-10.00 | 98% | 200TONS | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-12-26 | 1-Indanone-6-carboxylic acid
60031-08-5
|
$1.00 | 1KG | 99% | 10000KGS | Career Henan Chemical Co |
-
- 1-Indanone-6-carboxylic acid
60031-08-5
- $1.00-10.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-Indanone-6-carboxylic acid
60031-08-5
- $1.00
- 99%
- Career Henan Chemical Co
