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4-Isopropoxyaniline

CAS No.
7664-66-6
Chemical Name:
4-Isopropoxyaniline
Synonyms
AKOS BBB/094;AKOS BC-2569;4-isopropoxyanline;4-ISOPROPOXYANILINE;P-ISOPROPOXYANILINE;TIMTEC-BB SBB010330;4-ISOPROPOXYLANILINE;4-ISOPROPYLOXYANILINE;Tandutinib Impurity 4;4-Isopropoxyaniline>
CBNumber:
CB4715847
Molecular Formula:
C9H13NO
Molecular Weight:
151.21
MDL Number:
MFCD00059188
MOL File:
7664-66-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:48:27
Product description Number Pack Size Price
4-Isopropoxyaniline >98.0%(GC)(T) I0399 5g $19
4-Isopropoxyaniline >98.0%(GC)(T) I0399 25g $64
4-Isopropoxyaniline FI67289 0.05kg $207.68
4-Isopropoxyaniline FI67289 0.1kg $324.5
4-Isopropoxyaniline FI67289 0.25kg $519.2
More product size

4-Isopropoxyaniline Properties

Melting point 244 °C (decomp)
Boiling point 95°C 0,4mm
Density 1.03
refractive index 1.5430-1.5470
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form clear liquid
pka 6.15±0.10(Predicted)
color Colorless to Red to Green
LogP 1.620 (est)
CAS DataBase Reference 7664-66-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HazardClass  IRRITANT
HS Code  29214200
NFPA 704
0
2 0

4-Isopropoxyaniline price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical I0399 4-Isopropoxyaniline >98.0%(GC)(T) 7664-66-6 5g $19 2026-04-30 Buy
TCI Chemical I0399 4-Isopropoxyaniline >98.0%(GC)(T) 7664-66-6 25g $64 2026-04-30 Buy
Biosynth FI67289 4-Isopropoxyaniline 7664-66-6 0.05kg $207.68 2026-06-04 Buy
Biosynth FI67289 4-Isopropoxyaniline 7664-66-6 0.1kg $324.5 2026-06-04 Buy
Biosynth FI67289 4-Isopropoxyaniline 7664-66-6 0.25kg $519.2 2026-06-04 Buy
Product number Packaging Price Buy
I0399 5g $19 Buy
I0399 25g $64 Buy
FI67289 0.05kg $207.68 Buy
FI67289 0.1kg $324.5 Buy
FI67289 0.25kg $519.2 Buy

4-Isopropoxyaniline Chemical Properties,Uses,Production

Uses

4-Isopropoxyaniline is an aniline derivative used as a raw material or intermediate component in organic synthesis. It can be used in the preparation of pyrimidines and their derivatives. Anilines are toxic to humans and can cause strong skin and eye irritation on contact or ingestion, as well as some damage to the liver and kidneys.

Synthesis

4-Aminophenol

123-30-8

2-Bromopropane

75-26-3

4-Isopropoxyaniline

7664-66-6

GENERAL STEPS: The synthesis was carried out according to the one-step method reported by De Marco et al. 4-Aminophenol (92 mmol) and sodium hydride (suspension in mineral oil, 275 mmol) were added to anhydrous N,N-dimethylformamide (100 mL). Subsequently, 2-bromopropane (137 mmol) was added dropwise and the reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, distilled water (400 mL) was added to quench the reaction and the aqueous phase was extracted with ethyl acetate (3 x 150 mL). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The final product was purified by distillation under reduced pressure.

References

[1] Molecules, 2015, vol. 20, # 6, p. 9767 - 9787
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 20, p. 4898 - 4908
[3] Molecules, 2018, vol. 23, # 7,

4-Isopropoxyaniline Preparation Products And Raw materials

Global( 172)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Lidu New Material Technology Co., Ltd
+86-19307248857 +86-19307248857 19307248857@163.com China 885 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10236 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from 4-Isopropoxyaniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Isopropoxyaniline pictures 2026-06-04 4-Isopropoxyaniline
7664-66-6
1kg 97% 20 tons Hubei Lidu New Material Technology Co., Ltd
4-Isopropoxyaniline pictures 2019-07-06 4-Isopropoxyaniline
7664-66-6
$1.00 1kg 98% 200kg Career Henan Chemical Co
P-ISOPROPOXYANILINE 4-ISOPROPOXYBENZENAMINE:99+% 4-(propan-2-yloxy)aniline 4-isopropoxyanline AKOS BC-2569 AKOS BBB/094 4-ISOPROPOXYANILINE 4-ISOPROPOXYBENZENAMINE 4-ISOPROPOXY-PHENYLAMINE 4-ISOPROPOXYLANILINE 4-ISOPROPYLOXYANILINE TIMTEC-BB SBB010330 1,4-diethoxyanthracene-9,10-dione 4-Isopropoxyaniline> Tandutinib Impurity 4 Benzenamine, 4-(1-methylethoxy)- 4-(1-Methylethoxy)benzenamine 4-(1-Methylethoxy)-aniline 7664-66-6 7664-46-6 Anilines, Aromatic Amines and Nitro Compounds