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S-Adenosyl-L-methionine chloride salt

S-Adenosyl-L-methionine chloride salt structure

CAS No.: 24346-00-7

Chemical Name:: S-Adenosyl-L-methionine chloride salt

Synonyms: S-ADENOSYL-L-METHIONINE CHLORIDE;SAM-Cl;SAM CHLORIDE;Einecs 246-184-8;ACTIVE METHIONINE;SAM-E CHLORIDE SALT;ADEMETHIONINECHLORIDE;Active methionine chloride;ADENOSYL-L-METHIONINE CHLORIDE, S-;S-ADENOSYL METHIONINE CHLORIDE SALT

CBNumber:: CB4723189

Molecular Formula:: C15H23ClN6O5S

Molecular Weight:: 434.9

MDL Number:: MFCD00036337

MOL File:: 24346-00-7.mol

MSDS File:: SDS

Last updated:2026-09-12 18:52:57

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S-Adenosyl-L-methionine chloride salt Properties

storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	H₂O: 100 mg/mL
form	Solid
color	Off-White to Dark Yellow
Stability	Hygroscopic
FDA UNII	B02SK72839

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes	Xn
Risk Statements	20/21/22-68/20/21/22
Safety Statements	36-45
WGK Germany	1
F	10-21

S-Adenosyl-L-methionine chloride salt price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0450063	S-(5'-Adenosyl)-L-methionine chloride ≥98%	24346-00-7	5g	$1621	2026-06-04	Buy
Matrix Scientific	097918	5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride	24346-00-7	250.00mg	$515	2026-05-18	Buy
Matrix Scientific	097918	5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride	24346-00-7	1.00g	$1143	2026-05-18	Buy
ACHEMBLOCK	X217857	S-(5'-Adenosyl)-L-methionine chloride 98%	24346-00-7	10MG	$335	2026-05-27	Buy
ACHEMBLOCK	X217857	S-(5'-Adenosyl)-L-methionine chloride 98%	24346-00-7	25MG	$670	2026-05-27	Buy

Product number	Packaging	Price	Buy
CS-0450063	5g	$1621	Buy
097918	250.00mg	$515	Buy
097918	1.00g	$1143	Buy
X217857	10MG	$335	Buy
X217857	25MG	$670	Buy

S-Adenosyl-L-methionine chloride salt Chemical Properties, Uses, Production

Uses

S-(5'-Adenosyl)-L-methionine (chloride) is a Alkaloids product that can be isolated from From Saccharomyces Ceverisiae.[1].

Purification Methods

Purify it by ion exchange on Amberlite IRC-150 and eluting with 0.1-4M HCl. [Stolowitz & Minch J Am Chem Soc 103 6015 1981.] It has been isolated as the tri-reineckate salt by adding 2volumes of 1% solution of ammonium reineckate in 2% perchloric acid. The reineckate salt separates at once but is kept at 2o overnight. The salt is collected on a sintered glass funnel, washed with 0.5% of ammonium reineckate, dried (all operations at 2o) and stored at 2o. To obtain adenosylmethionine, the reineckate is dissolved in a small volume of methyl ethyl ketone (MEK) and centrifuged at room temperature to remove a small amount of solid. The clear dark red supernatant is extracted (in a separating funnel) with a slight excess of 0.1N H2SO4. The aqueous phase is re-extracted with fresh MEK until it is colourless. [Note that reineckates have UV absorption at 305nm ( 15,000), and the optical density at 305nm is used to detect and estimate reineckate ions.] MEK is removed from the aqueous layer containing adenosylmethionine sulfate; the pH is adjusted to 5.6-6.0 and extracted with two volumes of Et2O. The sulfate is obtained by evaporating the aqueous layer in vacuo. The hydrochloride can be obtained in the same way but using HCl instead of H2SO4. SAM-HCl has a solubility of 10% in H2O. The salts are stable in the cold at pH 4-6 but decompose in alkaline media. [Cantoni Biochemical Preparations 5 58 1957.] The purity of SAM can be determined by paper chromatography [Cantoni J Biol Chem 204 403 1953, Methods Enzymol 3 601 1957], electrophoretic methods or enzymic analysis [Cantoni & Vignos J Biol Chem 209 647 1954]. [Beilstein 26 III/IV 3676.]

S-Adenosyl-L-methionine chloride salt Preparation Products And Raw materials

Raw materials

Preparation Products

S-Adenosyl-L-methionine chloride salt Suppliers

Global Suppliers ( 61)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Hongene Biotech Corporation	021-64757213	info@hongene.com	China	672	61
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chengdu NoVi Biotechnology Co., Ltd.	028-81458053	novibiotech@163.com sales@novi-biotech.com	China	226	55
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7717	56
Shanghai YuLue Chemical Co., Ltd.	021-60345187 13671753212	lzz841106@aliyun.com	China	10244	55
Wuhan ChemFaces Biochemical Co., Ltd.	18607101326 15172504745	aileen@chemfaces.com	China	6904	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai GL Peptide Ltd.	+86-21-61263310 13764994101	fisherwang@glschina.com	China	8058	55
Aikon International Limited	025-58859352 19370895928	sales01@aikonchem.com	China	15078	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Hongene Biotech Corporation	61
Shanghai Hanhong Scientific Co.,Ltd.	64
Chengdu NoVi Biotechnology Co., Ltd.	55
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Shanghai YuLue Chemical Co., Ltd.	55
Wuhan ChemFaces Biochemical Co., Ltd.	55
EMMX Biotechnology LLC	60
Shanghai GL Peptide Ltd.	55
Aikon International Limited	58

View Latest Price from S-Adenosyl-L-methionine chloride salt manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-15	S-ADENOSYL-L-METHIONINE CHLORIDE SALT 24346-00-7	$1.00	100g	>98%		Career Henan Chemical Co

S-ADENOSYL-L-METHIONINE CHLORIDE SALT
24346-00-7
$1.00
>98%
Career Henan Chemical Co

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SAM-E CHLORIDE SALT SAM CHLORIDE ACTIVE METHIONINE ADENOSYL-L-METHIONINE, S-CHLORIDE SALT (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfaniumyl)butanoate hydrochloride S-ADENOSYL METHIONINE CHLORIDE SALT (3S)-5'-[(3-amino-3-carboxypropyl)methylsulphonio]-5'-deoxyadenosine chloride S-Adenosyl-5'-L-MethionineChlorideEx ADEMETHIONINECHLORIDE Active methionine, AdoMet, SAM chloride Active methionine chloride S-Adenosyl-5'-L-methionine chloride Einecs 246-184-8 ADENOSYL-L-METHIONINE CHLORIDE, S-(RG) S-(5′-Adenosyl)-L-methionine chloride,Active methionine, AdoMet, SAM chloride 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-adenosine chloride SAM-Cl S-ADENOSYL-L-METHIONINE CHLORIDE SALT USP/EP/BP ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride (2S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate hydrochloride ADENOSYL-L-METHIONINE CHLORIDE, S- S-(5'-Adenosyl)-L-methionine chloride S-ADENOSYL-L-METHIONINE CHLORIDE S-Adenosyl-L-methionine chloride salt 24346-00-7 C15H23ClN6O5S C15H23N6O5SCl Enzyme Cofactor BioChemical Cancer Research Chemopreventive Agents Amino Acids & Derivatives Bases & Related Reagents Carbohydrates & Derivatives Nucleotides Sulfur & Selenium Compounds