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DL-METHIONINE METHYLSULFONIUM CHLORIDE

DL-METHIONINE METHYLSULFONIUM CHLORIDE structure

CAS No.: 1115-84-0

Chemical Name:: DL-METHIONINE METHYLSULFONIUM CHLORIDE

Synonyms: MMSC;Methylmethionine;u-vit;yucron;C04078;cabagin;ardesyl;Vitas U;merastom;epadyn-u

CBNumber:: CB7249996

Molecular Formula:: C6H14ClNO2S

Molecular Weight:: 199.7

MDL Number:: MFCD00067196

MOL File:: 1115-84-0.mol

MSDS File:: SDS

Last updated:2026-05-28 03:20:59

Product description	Number	Pack Size	Price
L-Methionine-S-Methyl Sulfonium Chloride ≥95%	016116	500mg	$559
L-Methionine-S-Methyl Sulfonium Chloride ≥95%	016116	1g	$799
L-Methionine-S-methyl sulfonium chloride	FM25160	0.25g	$227.15
L-Methionine-S-methyl sulfonium chloride	FM25160	0.5g	$421.85
L-Methionine-S-methyl sulfonium chloride	FM25160	1g	$778.8
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DL-METHIONINE METHYLSULFONIUM CHLORIDE Properties

Melting point	134 °C (decomp)
FEMA	3445 \| DL-(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE
storage temp.	Hygroscopic, Refrigerator, Under inert atmosphere
solubility	Water (Soluble), Methanol (Slightly)
form	Solid
color	White to Off-White
Odor	at 100.00 %. malty tomato potato sulfury green
Odor Type	malty
JECFA Number	1427
Stability	Hygroscopic
LogP	0.28
CAS DataBase Reference	1115-84-0(CAS DataBase Reference)
FDA UNII	G9CUR2204U
ATC code	A02BX04

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Toxicity	LD50 oral in rat: > 6gm/kg

DL-METHIONINE METHYLSULFONIUM CHLORIDE price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	016116	L-Methionine-S-Methyl Sulfonium Chloride ≥95%	1115-84-0	500mg	$559	2026-06-03	Buy
Usbiological	016116	L-Methionine-S-Methyl Sulfonium Chloride ≥95%	1115-84-0	1g	$799	2026-06-03	Buy
Biosynth	FM25160	L-Methionine-S-methyl sulfonium chloride	1115-84-0	0.25g	$227.15	2026-06-04	Buy
Biosynth	FM25160	L-Methionine-S-methyl sulfonium chloride	1115-84-0	0.5g	$421.85	2026-06-04	Buy
Biosynth	FM25160	L-Methionine-S-methyl sulfonium chloride	1115-84-0	1g	$778.8	2026-06-04	Buy

Product number	Packaging	Price	Buy
016116	500mg	$559	Buy
016116	1g	$799	Buy
FM25160	0.25g	$227.15	Buy
FM25160	0.5g	$421.85	Buy
FM25160	1g	$778.8	Buy

DL-METHIONINE METHYLSULFONIUM CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

Naturally occurs as the L-form in a variety of vegetables. Although used in food as a flavoring ingredient in fish products, it has also been used therapeutically in the treatment of peptic ulcers, colitis and gastritis.

Originator

Cabagin-U,Kowa

Occurrence

Reported found in asparagus, cabbage, cabbage juice, celery, sweet corn, milk, potato, tea, green tea and tomato.

Uses

A derivative of L-Methionine (M260440). Naturally occurring sulfonium compound found in a large number of plants. Identification of antiulcer vitamin in cabbage leaves. Antiulcerative.

Definition

ChEBI: Methylmethionine sulfonium salt is an organic molecular entity.

Application

Methiosulfonium chloride is used for its protective effect on the liver and gastrointestinal mucosa, whereas the iodide finds use for rheumatic disorders.

Manufacturing Process

298 g dl-methionine, 2000 ml water and 151.1 methyl chloride were put into autoclave (volume 3 L) made from V4-a steel. The mixture was heated at temperature 50°-55°C for 8 hours and pressure 12-13 atmospheres.
On cooling an excess of methyl chloride was evaporated, the slightly yellow residue was mixed with 0.2% activated coal and filtered. Water was evaporated in vacuum at 45°-55°C. 2 L methanol was poured into an almost colorless syrup obtained, cooled to -5°-(-10°)C. The methylmethioninesulfonium chloride crystallized.
It was filtered off to give 340 g (85.3%) of desired product 99.5 % purity (data of thin-layer chromatography).

Therapeutic Function

Hepatoprotectant

Taste threshold values

Taste characteristics at 5 ppm: sulfureous creamy, tomato, malty, vegetable like

Trade name

Chloride: Ardesyl (Beytout, France), withdrawn from the market; Cabagin (Kowa, Japan). Iodide: Lobarthrose (Opodex, France), withdrawn from the market.

Purification Methods

Likely impurities are methionine, methionine sulfoxide and methionine sulfone. Crystallise Vitamin U from water by adding a large excess of EtOH. It is hygroscopic. It should be stored in a cool, dry place and protected from light. It has also been purified on a column of Dowex 50 H+ form, washed with H2O and eluted with 6N ammonia, lyophilised, the residue is dissolved in dilute HCl, lyophilised again and then it is obtained as colourless prisms by vapour diffusion of Et2O in a 1:1 (v/v) mixture of MeOH/EtOH in which the hydrochloride is dissolved [Del Re Acta Cryst B 33 3289 1977]. The iodide salt, m ~ 150o(dec), is obtained by dissolving it in 50% aqueous EtOH and adding ~3.5 volumes of absolute EtOH. The bromide salt has m 140o(dec) [Toennies & Kolb J Amer Chem Soc 67 849 1945].

DL-METHIONINE METHYLSULFONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Chloromethane DL-Methionine

Preparation Products

DL-METHIONINE METHYLSULFONIUM CHLORIDE Suppliers

Global( 74)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19935	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 17389186172	1077@dideu.com	China	3999	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
Hebei Zhanyao Biotechnology Co. Ltd	15369953316 +8615369953316	admin@zhanyaobio.com	China	2115	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +8619957148339	market18@leapchem.com	China	24569	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49709	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49859	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Hebei Zhanyao Biotechnology Co. Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from DL-METHIONINE METHYLSULFONIUM CHLORIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-08-07	L-Methionine-S-Methyl SulfoniuM Chloride 1115-84-0	$1.00	1KG	99%	200000KG	Shaanxi Dideu Medichem Co. Ltd
	2021-10-19	Methyl Methanesulfonate 1115-84-0	$10.00	1Kg/Bag	99%	20 Tons	Hebei Zhanyao Biotechnology Co. Ltd

L-Methionine-S-Methyl SulfoniuM Chloride
1115-84-0
$1.00
99%
Shaanxi Dideu Medichem Co. Ltd

Methyl Methanesulfonate
1115-84-0
$10.00
99%
Hebei Zhanyao Biotechnology Co. Ltd

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(3-amino-3-carboxypropyl)dimethyl-,chloride,(s)-sulfoniu (3-amino-3-carboxypropyl)dimethyl-,chloride,l-sulfoniu (3-amino-3-carboxypropyl)dimethyl-,chloride,L-Sulfonium VITAMIN U VITAMIN U CHLORIDE ardesyl cabagin cabaginu epadyn-u merastom methylmethioninesulfoniumchloride s-methymethioninechloride u-vit yucron S-methylmethioninium chloride (S)-(3-Amino-3-carboxypropyl)dimethyl sulfonium chloride L-MethionineS-methylsulfoniumchloride Sulfonium, (3S)-3-amino-3-carboxypropyldimethyl-, chloride METHIOSULFONIUMCHLORIDE S-METHYLMETHIONINESULFONIUM CHLORIDE S-METHYL-DL-METHIONINE-SULFONIUMCHLORIDE (3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE DL-METHIONINE METHYLSULFONIUM CHLORIDE DL-METHYLMETHIONINE SULFONIUMCHLORIDE DL-(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE METHYL-METHIONINE SULPHONIUM CHLORIDE DL-(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULPHONIUMCHLORIDE Vitamin U,chlorine type L-Methionine methylsulfonium chloride VITAMIN U (USP) (S-METHYLMETHIONINESULFONIUM CHLORIDE) [(3S)-3-AMino-3-carboxypropyl](diMethyl)sulfoniuM Chloride L-(3-AMino-3-carboxypropyl)(diMethyl)sulfoniuM Chloride S-MethylMethionine Chloride Vitas U [(3S)-3-amino-3-carboxypropyl]-dimethylsulfanium:chloride L-Methylmethionine sulfonium chloride Methionine methylsulfonium chloride C04078 Methylmethionine sulfonium salt Pardoprunox Impurity 26 Decarboxylated (S)-Adenosyl Methionine Tritrifluoromethanesulfonic Acid S-Methylmethioniniumchlorid Methylmethionine MMSC 1115-84-0 115-84-0 C6H14NO2SCl C6H16ClNO2S Modified Amino Acids I - Z Sulfonium Compounds Iodonium Sulfonium & Oxonium Compounds BioChemical Amino Acids and Peptides Biochemicals and Reagents Vitamins and derivatives Amino Acids & Derivatives Sulfur & Selenium Compounds