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4'-(TRIFLUOROMETHYL)PROPIOPHENONE

4'-(TRIFLUOROMETHYL)PROPIOPHENONE structure

CAS No.: 711-33-1

Chemical Name:: 4'-(TRIFLUOROMETHYL)PROPIOPHENONE

Synonyms: p-trifluoromethylpropiophenone;4-(TRIFLUOROMETHYL)PROPIOPHENONE;4'-(trifluoromethyl)propiophenone;4'-(Trifluoromethyl)propiophenone 97%;4'-(Trifluoromethyl)propiophenone,97%;Ethyl 4-(trifluoromethyl)phenyl ketone;p-Trifluoromethylpropiophenone, min. 97%;1-[4-(Trifluoromethyl)phenyl]-1-propanone;1-(4-(trifluoromethyl)phenyl)propan-1-one;1-Propanone, 1-[4-(trifluoromethyl)phenyl]-

CBNumber:: CB4723967

Molecular Formula:: C10H9F3O

Molecular Weight:: 202.17

MDL Number:: MFCD00039231

MOL File:: 711-33-1.mol

MSDS File:: SDS

Last updated:2026-05-28 01:56:59

Product description	Number	Pack Size	Price
1-[4-(Trifluoromethyl)phenyl]propan-1-one min. 98.0 %	T4250	5G	$63
4'-(Trifluoromethyl)propiophenone	006493	25.00g	$38
4'-(Trifluoromethyl)propiophenone	006493	100.00g	$146
4'-(Trifluoromethyl)propiophenone	006493	500.00g	$699
1-(4-(Trifluoromethyl)phenyl)propan-1-one 97%	T54064	1g	$13
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4'-(TRIFLUOROMETHYL)PROPIOPHENONE Properties

Melting point	36-39 °C(lit.)
Boiling point	216 °C(lit.)
Density	1,973 g/cm³
Flash point	210 °F
storage temp.	Inert atmosphere,Room Temperature
form	fused solid
color	White/colourless
BRN	1874014
InChI	1S/C10H9F3O/c1-2-9(14)7-3-5-8(6-4-7)10(11,12)13/h3-6H,2H2,1H3
InChIKey	QFKOWENRSZZLPK-UHFFFAOYSA-N
SMILES	CCC(=O)c1ccc(cc1)C(F)(F)F
CAS DataBase Reference	711-33-1(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

HazardClass

IRRITANT

HS Code

29147000

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
0		0

4'-(TRIFLUOROMETHYL)PROPIOPHENONE price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	T4250	1-[4-(Trifluoromethyl)phenyl]propan-1-one min. 98.0 %	711-33-1	5G	$63	2026-04-30	Buy
Matrix Scientific	006493	4'-(Trifluoromethyl)propiophenone	711-33-1	25.00g	$38	2026-05-18	Buy
Matrix Scientific	006493	4'-(Trifluoromethyl)propiophenone	711-33-1	100.00g	$146	2026-05-18	Buy
Matrix Scientific	006493	4'-(Trifluoromethyl)propiophenone	711-33-1	500.00g	$699	2026-05-18	Buy
Synthonix	T54064	1-(4-(Trifluoromethyl)phenyl)propan-1-one 97%	711-33-1	1g	$13	2026-05-06	Buy

Product number	Packaging	Price	Buy
T4250	5G	$63	Buy
006493	25.00g	$38	Buy
006493	100.00g	$146	Buy
006493	500.00g	$699	Buy
T54064	1g	$13	Buy

4'-(TRIFLUOROMETHYL)PROPIOPHENONE Chemical Properties,Uses,Production

Chemical Properties

solid

Uses

4-(Trifluoromethyl)propiophenone is used as a reagent in the preparation of ketones and alcohols in organic synthesis. It is also used as a starting material for the synthesis of various compounds such as 4-(trifluoromethyl)phenylacetic acid, which is used as a building block in the synthesis of pharmaceuticals.

Synthesis

1-[4-(TRIFLUOROMETHYL)PHENYL]PROPAN-1-OL

67081-98-5

711-33-1

General procedure for the synthesis of 4-(trifluoromethyl)propiophenone from 1-(4-trifluoromethylphenyl)-1-propanol: First, a solution of 1-(4-trifluoromethylphenyl)-1-propanol prepared in step 1 was mixed with 3.9 kg of tetrabutylammonium hydrogensulphate and 12.3 kg of sodium dihydrogen phosphate dihydrate and dissolved in 32 L of deionized water. Subsequently, the mixture was washed with 10 L of deionized water, and then 318 kg of a 12% aqueous sodium perchlorate solution was added to the mixture, followed by washing the reaction mixture with 35 L of deionized water. The resulting solution was allowed to stand for 30 minutes before the organic layer was separated and mixed with 358 L of deionized water and 18 kg of 38% hydrochloric acid and stirred for 5 minutes. The organic layer was separated and washed with deionized water to finally obtain 378 kg of 4-(trifluoromethyl)propiophenone from the organic layer (yield: 97.2%).

References

[1] Synthetic Communications, 1989, vol. 19, # 9-10, p. 1735 - 1744
[2] Patent: WO2006/112565, 2006, A1. Location in patent: Page/Page column 16-17
[3] Journal of Medicinal Chemistry, 1995, vol. 38, # 20, p. 3918 - 3932
[4] European Journal of Medicinal Chemistry, 1995, vol. 30, # 1, p. 85 - 94
[5] Journal of Organic Chemistry, 2003, vol. 68, # 4, p. 1594 - 1596

4'-(TRIFLUOROMETHYL)PROPIOPHENONE synthesis

Synthesis of 4'-(TRIFLUOROMETHYL)PROPIOPHENONE from 2-Bromobenzotrifluoride and Propionic anhydride

4'-(TRIFLUOROMETHYL)PROPIOPHENONE Preparation Products And Raw materials

Raw materials

PHENYL 4‐(TRIFLUOROMETHYL)BENZOATE Benzene, 1-(1-propynyl)-4-(trifluoromethyl)- Benzene, 1-(1E)-1-propen-1-yl-4-(trifluoromethyl)- Lithium, [4-(trifluoromethyl)phenyl]- 1-(4-(trifluoromethyl)phenyl)prop-2-en-1-ol

alpha,alpha,alpha-Trifluoro-o-toluoyl chloride 1-[4-(TRIFLUOROMETHYL)PHENYL]PROPAN-1-OL 4'-(Trifluoromethyl)acetophenone 1-(4-(trifluoroMethyl)phenyl)propan-2-one N-METHOXY-N-METHYL-PROPIONAMIDE

2-Bromobenzotrifluoride Bromoethane 4-(Trifluoromethyl)benzoic acid 4-Bromobenzotrifluoride

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Preparation Products

2-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]PROPAN-1-ONE

4'-(TRIFLUOROMETHYL)PROPIOPHENONE Suppliers

Global( 141)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971	deasea125996@gmail.com	China	2472	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	10000	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	17259	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Shaanxi Dideu Medichem Co. Ltd	58
CD Chemical Group Limited	58

View Lastest Price from 4'-(TRIFLUOROMETHYL)PROPIOPHENONE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	4'-(TRIFLUOROMETHYL)PROPIOPHENONE 711-33-1	$10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2024-04-24	4'-(Trifluoromethyl)propiophenone 711-33-1	$30.00-100.00	1kg	99.93%	1000kg per week	Ouhuang Engineering Materials (Hubei) Co., Ltd
2023-08-18	4'-(TRIFLUOROMETHYL)PROPIOPHENONE 711-33-1	$50.00	1kg	99.9%	10000MT	Henan Bao Enluo International TradeCo.，LTD

4'-(TRIFLUOROMETHYL)PROPIOPHENONE
711-33-1
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

4'-(Trifluoromethyl)propiophenone
711-33-1
$30.00-100.00
99.93%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4'-(TRIFLUOROMETHYL)PROPIOPHENONE
711-33-1
$50.00
99.9%
Henan Bao Enluo International TradeCo.，LTD

4'-(TRIFLUOROMETHYL)PROPIOPHENONE Spectrum

4'-(TRIFLUOROMETHYL)PROPIOPHENONE(711-33-1)¹HNMR

711-33-1(4'-(TRIFLUOROMETHYL)PROPIOPHENONE)Related Search:

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4'-(Trifluoromethyl)propiophenone,97% 4'-(Trifluoromethyl)propiophenone 97% 1-(4-(trifluoromethyl)phenyl)propan-1-one p-Trifluoromethylpropiophenone, min. 97% 1-[4-(Trifluoromethyl)phenyl]-1-propanone Ethyl 4-(trifluoromethyl)phenyl ketone 4-(TRIFLUOROMETHYL)PROPIOPHENONE p-trifluoromethylpropiophenone 1-Propanone, 1-[4-(trifluoromethyl)phenyl]- 1-[4-(trifluoromethyl)phenyl]propan-1-one 4'-(TRIFLUOROMETHYL)PROPIOPHENONE 4'-(trifluoromethyl)propiophenone 4′-(Trifluoromethyl)propiophenone, CAS 711-33-1 711-33-1 Carbonyl Compounds C10 Building Blocks Ketones Organic Building Blocks KETONE C10 Carbonyl Compounds Ketones