ChemicalBook >> CAS DataBase List >>4-(Trifluoromethyl)benzoic acid
4-(Trifluoromethyl)benzoic acid
- CAS No.
- 455-24-3
- Chemical Name:
- 4-(Trifluoromethyl)benzoic acid
- Synonyms
- PTF;P-TRIFLUOROMETHYLBENZOIC ACID;PTF-BOA;C 71640;CF3-C6H4-COOH;p-benzoic Acid;RARECHEM AL BO 0066;TIMTEC-BB SBB008571;p-Trifluoromethylbenzoic;P-CARBOXYBENZOTRIFLUORIDE
- CBNumber:
- CB7377273
- Molecular Formula:
- C8H5F3O2
- Molecular Weight:
- 190.12
- MDL Number:
- MFCD00002562
- MOL File:
- 455-24-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:53:06
| Melting point | 219-220 °C(lit.) |
|---|---|
| Boiling point | 247°C 753mm |
| Density | 1.3173 (estimate) |
| Flash point | 247°C/753mm |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.69±0.10(Predicted) |
| form | Fine Crystalline Powder |
| color | White to slight gray |
| Water Solubility | Soluble in water. |
| BRN | 2049241 |
| InChI | InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13) |
| InChIKey | SWKPKONEIZGROQ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(C(F)(F)F)C=C1 |
| CAS DataBase Reference | 455-24-3(CAS DataBase Reference) |
| FDA UNII | KA05X8S21Z |
| NIST Chemistry Reference | «ALPHA»,«alpha»,«alpha»-trifluoro-p-toluic acid(455-24-3) |
| EPA Substance Registry System | Benzoic acid, 4-(trifluoromethyl)- (455-24-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
4-(Trifluoromethyl)benzoic acid price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 196894 | 4-(Trifluoromethyl)benzoic acid 98% | 455-24-3 | 5g | $67.8 | 2026-04-30 | Buy |
| TCI Chemical | T1145 | 4-(Trifluoromethyl)benzoic Acid >98.0%(T) | 455-24-3 | 5g | $45 | 2026-04-30 | Buy |
| TCI Chemical | T1145 | 4-(Trifluoromethyl)benzoic Acid >98.0%(T) | 455-24-3 | 25g | $134 | 2026-04-30 | Buy |
| ChemScene | CS-W015914 | 4-(Trifluoromethyl)benzoic acid ≥98% | 455-24-3 | 25g | $8 | 2026-06-04 | Buy |
| ChemScene | CS-W015914 | 4-(Trifluoromethyl)benzoic acid ≥98% | 455-24-3 | 100g | $21 | 2026-06-04 | Buy |
4-(Trifluoromethyl)benzoic acid Chemical Properties, Uses, Production
Uses
4-(Trifluoromethyl)benzaldehyde is a reactant that has been used in the preparation of N,N'-(Arylmethylene)bisamides with cytotoxic activity as anti cancer agents.
Chemical Properties
White to light yellow crystal powde
Uses
4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates viaN,N-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.
Definition
ChEBI: A benzoic acid carrying a 4-trifluoromethyl substituent.
4-(Trifluoromethyl)benzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global Suppliers ( 498)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Qingdao and Fine Chemical Co., Ltd. - | 0532-66915948 | sxq@unionfinechem.com | China | 46 | 62 |
| Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. | 13396369453 18678026865 | sdfantai@163.com | China | 904 | 58 |
| Jiangsu Chromene New Material Technology Co., Ltd | 15358977508 | lengyan1114@126.com | China | 21 | 58 |
| Changzhou Aifa Technology Co., Ltd | 0519-89892883 | jsafkj@126.com | China | 15 | 58 |
| Taoeng (Shandong) Chemicals Co., Ltd. | 15244440883 15244440883 | 2905712029@qq.com | China | 77 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd. | 0519-85195575 15861192208;15861192208;13685253038 | 850305@sunkechem.com | China | 72 | 69 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
Related articles
- 4-(Trifluoromethyl)benzoic Acid: Synthesis, Antifungal Esters, and Analytical Applications
- 4-(Trifluoromethyl)benzoic acid synthesizes salicylanilide esters with antifungal activity, serves as a GC/MS internal standar....
- Jun 27,2025
View Latest Price from 4-(Trifluoromethyl)benzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 4-(Trifluoromethyl)benzoic acid
455-24-3
|
$5.00 | 1kg | ≥99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-09-17 | 4-(Trifluoromethyl) benzoic acid
455-24-3
|
$45.00 | 1KG | 99% | 300MT/year | Speranza Chemical Co., Ltd. | |
 |
2026-09-17 | 4-(Trifluoromethyl)benzoic acid
455-24-3
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- 4-(Trifluoromethyl)benzoic acid
455-24-3
- $5.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 4-(Trifluoromethyl) benzoic acid
455-24-3
- $45.00
- 99%
- Speranza Chemical Co., Ltd.
-
- 4-(Trifluoromethyl)benzoic acid
455-24-3
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
455-24-3 (4-(Trifluoromethyl)benzoic acid) Related Search:
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4-(TRIFLUOROMETHYL)BENZOIC ACID
A,A,A-TRIFLUORO-P-TOLUIC ACID
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PTF-BOA
RARECHEM AL BO 0066
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p-Trifluoromethylbenzoic Acid 4-Trifluoromethylbenzoic Acid
4-TRIFLUOROMETHYL BENZOIC ACID FINE GRADE
4-TRIFLUOROMETHYL BENZOIC ACID TECHNICAL GRADE
α,α,α-Trifluoro-p-toluic acid, 4-Carboxybenzotrifluoride
C 71640
4-(Trifluoromethyl)benzoic acid ,99%
p-Trifluoromethylbenzoic acid, min. 98%
p-benzoic Acid
Alpha-Trifluoro-p-toluic acid
4-Carboxybenzotrifluoride, alpha,alpha,alpha-Trifluoro-p-toluic acid
4- threefluorine Methyl benzoic acid
The three fluorinated Methyl benzoic acid
CAS No.455-24-3 4-(Trifluoromethyl)benzoic acid
4-methyl-N'-(4- (trifluoromethyl)benzylidene)benzenesulfonohydrazide
4-(Trifluoromethyl)benzoic acid , 4-(Trifluoromethyl)benzoic acid
CF3-C6H4-COOH
P-TRIFLUOROMETHYLBENZOIC ACID
PTF
455-24-3
455-24-31
Organic Building Blocks
CARBOXYLIC ACID
Carboxylic Acids
Carbonyl Compounds
C8
Building Blocks
Benzotrifluoride Series
Carboxylic Acids
Phenyls & Phenyl-Het
blocks
Carboxes
Boronic Acid series
Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
Carboxylic Acids
Phenyls & Phenyl-Het
API intermediates
bc0001
