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4-(Trifluoromethyl)benzoic acid

CAS No.
455-24-3
Chemical Name:
4-(Trifluoromethyl)benzoic acid
Synonyms
PTF;P-TRIFLUOROMETHYLBENZOIC ACID;PTF-BOA;C 71640;CF3-C6H4-COOH;p-benzoic Acid;RARECHEM AL BO 0066;TIMTEC-BB SBB008571;p-Trifluoromethylbenzoic;P-CARBOXYBENZOTRIFLUORIDE
CBNumber:
CB7377273
Molecular Formula:
C8H5F3O2
Molecular Weight:
190.12
MDL Number:
MFCD00002562
MOL File:
455-24-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:53:06
Product description Number Pack Size Price
4-(Trifluoromethyl)benzoic acid 98% 196894 5g $67.8
4-(Trifluoromethyl)benzoic Acid >98.0%(T) T1145 5g $45
4-(Trifluoromethyl)benzoic Acid >98.0%(T) T1145 25g $134
4-(Trifluoromethyl)benzoic acid ≥99%(Assay) 45386 5G $17.3
4-(Trifluoromethyl)benzoic acid ≥99%(Assay) 45386 25G $25
More product size

4-(Trifluoromethyl)benzoic acid Properties

Melting point 219-220 °C(lit.)
Boiling point 247°C 753mm
Density 1.3173 (estimate)
Flash point 247°C/753mm
storage temp. Sealed in dry,Room Temperature
pka 3.69±0.10(Predicted)
form Fine Crystalline Powder
color White to slight gray
Water Solubility Soluble in water.
BRN 2049241
InChI InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)
InChIKey SWKPKONEIZGROQ-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC=C(C(F)(F)F)C=C1
CAS DataBase Reference 455-24-3(CAS DataBase Reference)
FDA UNII KA05X8S21Z
NIST Chemistry Reference «ALPHA»,«alpha»,«alpha»-trifluoro-p-toluic acid(455-24-3)
EPA Substance Registry System Benzoic acid, 4-(trifluoromethyl)- (455-24-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37-24/25
WGK Germany  3
TSCA  TSCA listed
HazardClass  IRRITANT
HS Code  29163900
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

4-(Trifluoromethyl)benzoic acid price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 196894 4-(Trifluoromethyl)benzoic acid 98% 455-24-3 5g $67.8 2026-04-30 Buy
TCI Chemical T1145 4-(Trifluoromethyl)benzoic Acid >98.0%(T) 455-24-3 5g $45 2026-04-30 Buy
TCI Chemical T1145 4-(Trifluoromethyl)benzoic Acid >98.0%(T) 455-24-3 25g $134 2026-04-30 Buy
Chem-Impex 45386 4-(Trifluoromethyl)benzoic acid ≥99%(Assay) 455-24-3 5G $17.3 2026-05-19 Buy
Chem-Impex 45386 4-(Trifluoromethyl)benzoic acid ≥99%(Assay) 455-24-3 25G $25 2026-05-19 Buy
Product number Packaging Price Buy
196894 5g $67.8 Buy
T1145 5g $45 Buy
T1145 25g $134 Buy
45386 5G $17.3 Buy
45386 25G $25 Buy

4-(Trifluoromethyl)benzoic acid Chemical Properties,Uses,Production

Uses

4-(Trifluoromethyl)benzaldehyde is a reactant that has been used in the preparation of N,N'-(Arylmethylene)bisamides with cytotoxic activity as anti cancer agents.

Chemical Properties

White to light yellow crystal powde

Uses

4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates viaN,N-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

Definition

ChEBI: A benzoic acid carrying a 4-trifluoromethyl substituent.

455-19-6
455-24-3
Synthesis of 4-(Trifluoromethyl)benzoic acid from 4-(Trifluoromethyl)benzaldehyde
Global( 490)Suppliers
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Shanghai Cube Chemical Co., Ltd.
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Capot Chemical Co.,Ltd.
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View Lastest Price from 4-(Trifluoromethyl)benzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(Trifluoromethyl) benzoic acid pictures 2026-05-29 4-(Trifluoromethyl) benzoic acid
455-24-3
$45.00 1KG 99% 300MT/year Speranza Chemical Co., Ltd.
4-(Trifluoromethyl)benzoic acid pictures 2026-05-29 4-(Trifluoromethyl)benzoic acid
455-24-3
1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
4-(Trifluoromethyl)benzoic acid pictures 2026-05-21 4-(Trifluoromethyl)benzoic acid
455-24-3
$5.00 1kg ≥99% 100mt/year Jinan Finer Chemical Co., Ltd
4-(trifluoromethyl)-benzoicaci Benzoic acid, 4-(trifluoromethyl)- 4-(TRIFLUOROMETHYL)BENZOIC ACID A,A,A-TRIFLUORO-P-TOLUIC ACID ALPHA,ALPHA,ALPHA-TRIFLUORO-P-TOLUIC ACID PTF-BOA RARECHEM AL BO 0066 P-CARBOXYBENZOTRIFLUORIDE TIMTEC-BB SBB008571 p-Trifluoromethylbenzoic p-Trifluoromethylbenzoicacid,min.98% à,à,à-trifluoro-p-toluic acid α,α,α-trifluoro-p-toluic acid 4-(Trifluoromethyl)benzoicacid98% 4-CARBOXYBENZOTRIFLUORIDE p-Trifluoromethylbenzoic Acid 4-Trifluoromethylbenzoic Acid 4-TRIFLUOROMETHYL BENZOIC ACID FINE GRADE 4-TRIFLUOROMETHYL BENZOIC ACID TECHNICAL GRADE α,α,α-Trifluoro-p-toluic acid, 4-Carboxybenzotrifluoride C 71640 4-(Trifluoromethyl)benzoic acid ,99% p-Trifluoromethylbenzoic acid, min. 98% p-benzoic Acid Alpha-Trifluoro-p-toluic acid 4-Carboxybenzotrifluoride, alpha,alpha,alpha-Trifluoro-p-toluic acid 4- threefluorine Methyl benzoic acid The three fluorinated Methyl benzoic acid CAS No.455-24-3 4-(Trifluoromethyl)benzoic acid 4-methyl-N'-(4- (trifluoromethyl)benzylidene)benzenesulfonohydrazide 4-(Trifluoromethyl)benzoic acid , 4-(Trifluoromethyl)benzoic acid CF3-C6H4-COOH P-TRIFLUOROMETHYLBENZOIC ACID PTF 455-24-3 455-24-31 Organic Building Blocks CARBOXYLIC ACID Carboxylic Acids Carbonyl Compounds C8 Building Blocks Benzotrifluoride Series Carboxylic Acids Phenyls & Phenyl-Het blocks Carboxes Boronic Acid series Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Carboxylic Acids Phenyls & Phenyl-Het API intermediates bc0001