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(R)-3-Aminopyrrolidine

(R)-3-Aminopyrrolidine structure

CAS No.: 116183-82-5

Chemical Name:: (R)-3-Aminopyrrolidine

Synonyms: R-AP;MYP23;alpha-2-MRAP;CAS:116183-82-5;3-amino-R-pyrrolidine;(R)-pyrrolidin-3-amine;(R)-3-AMINOPYRROLIDINE;(3R)-3-Pyrrolidinamine;(3R)-pyrrolidin-3-aMine;(3R)-Pyrrolidine-3-amine

CBNumber:: CB4730772

Molecular Formula:: C4H10N2

Molecular Weight:: 86.14

MDL Number:: MFCD00143190

MOL File:: 116183-82-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:03:05

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(R)-3-Aminopyrrolidine Properties

Boiling point	164-165 °C(lit.)
Density	0.984 g/mL at 25 °C(lit.)
refractive index	n20/D 1.489(lit.)
Flash point	147 °F
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	9.94±0.20(Predicted)
form	clear liquid
color	Colorless to Almost colorless
optical activity	[α]/D +20°, neat
InChI	1S/C4H10N2/c5-4-1-2-6-3-4/h4,6H,1-3,5H2/t4-/m1/s1
InChIKey	NGXSWUFDCSEIOO-SCSAIBSYSA-N
SMILES	N[C@@H]1CCNC1
CAS DataBase Reference	116183-82-5(CAS DataBase Reference)
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P280-P301+P330+P331-P303+P361+P353-P305+P351+P338+P310

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

RIDADR

NA 1993 / PGIII

WGK Germany

HazardClass

PackingGroup

III

HS Code

29339900

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Eye Dam. 1
Skin Corr. 1B

NFPA 704

	2
0		0

(R)-3-Aminopyrrolidine price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	540781	(R)-(+)-3-Aminopyrrolidine 98%	116183-82-5	1g	$262	2026-04-30	Buy
TCI Chemical	A1167	(3R)-(+)-3-Aminopyrrolidine >98.0%(GC)(T)	116183-82-5	5g	$228	2026-04-30	Buy
TCI Chemical	A1167	(3R)-(+)-3-Aminopyrrolidine >98.0%(GC)(T)	116183-82-5	25g	$862	2024-03-01	Buy
Usbiological	261472	(3R)-(+)-3-Aminopyrrolidine Asreported	116183-82-5	1g	$325	2026-06-03	Buy
Usbiological	261472	(3R)-(+)-3-Aminopyrrolidine Asreported	116183-82-5	2g	$452	2026-06-03	Buy

Product number	Packaging	Price	Buy
540781	1g	$262	Buy
A1167	5g	$228	Buy
A1167	25g	$862	Buy
261472	1g	$325	Buy
261472	2g	$452	Buy

(R)-3-Aminopyrrolidine Chemical Properties,Uses,Production

Synthesis

114715-38-7

79286-79-6

General procedure for the synthesis of (S)-3-aminopyrrolidine from (S)-1-benzyl-3-aminopyrrolidine: 7.0 g of (S)-1-benzyl-3-aminopyrrolidine, 25 mL of methanol, and 0.7 g of 5% Pd/C catalyst were added to a 100 mL autoclave. The hydrogen pressure was adjusted to 1 MPa, the temperature was raised to 70 °C and the reaction was kept stirring for 8 hours. Upon completion of the reaction, it was cooled to room temperature and the pressure was slowly released. The reaction mixture was filtered to remove the catalyst and the mother liquor was concentrated and purified by distillation to collect the 80-83 °C/40 kPa fraction to give 3.2 g of (S)-3-aminopyrrolidine. The product was analyzed with 99% chemical purity and 90% optical purity e.e.

References

[1] Patent: US6348600, 2002, B1. Location in patent: Page column 14
[2] Patent: EP1640364, 2006, A1. Location in patent: Page/Page column 10
[3] Patent: EP1236716, 2002, A1. Location in patent: Example 6

(R)-3-Aminopyrrolidine Preparation Products And Raw materials

Raw materials

(S)-(+)-1-Benzyl-3-aminopyrrolidine (S)-3-(Boc-amino)pyrrolidine Methanol Hydrogen

Preparation Products

(R)-3-(Boc-amino)pyrrolidine

(R)-3-Aminopyrrolidine Suppliers

Global( 169)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Kangyue Huilan Pharmaceutical Technology Co., Ltd	028-81092800 17323275954	2567869566@qq.com	China	444	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Sichuan Guanghan Bio-Tech Co., Ltd	+86-28-86127071	info@sino-produce.com	China	400	66
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
China DongFan Chemical Co.,LTD	86-0571-85151182		China	5681	66

Supplier	Advantage
Kangyue Huilan Pharmaceutical Technology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66
Sichuan Guanghan Bio-Tech Co., Ltd	66
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
China DongFan Chemical Co.,LTD	66

View Lastest Price from (R)-3-Aminopyrrolidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2019-07-06	(R)-3-Aminopyrrolidine 116183-82-5	$1.00	1KG	96%	500kg	Career Henan Chemical Co
2019-07-06	(R)-3-Aminopyrrolidine 116183-82-5	$1.00	1KG	96%	500kg	Career Henan Chemical Co
2019-07-06	(R)-3-Aminopyrrolidine 116183-82-5	$1.00	1KG	96%	500kg	Career Henan Chemical Co

(R)-3-Aminopyrrolidine
116183-82-5
$1.00
96%
Career Henan Chemical Co

(R)-3-Aminopyrrolidine
116183-82-5
$1.00
96%
Career Henan Chemical Co

(R)-3-Aminopyrrolidine
116183-82-5
$1.00
96%
Career Henan Chemical Co

(R)-3-Aminopyrrolidine Spectrum

(R)-3-Aminopyrrolidine(116183-82-5)MS (R)-3-Aminopyrrolidine(116183-82-5)IR1

116183-82-5((R)-3-Aminopyrrolidine)Related Search:

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(3R)-(-)-3-Aminopyrrolidine dihydrochloride (3S)-(-)-3-(Dimethylamino)pyrrolidine (3R)-(+)-3-Acetamidopyrrolidine Methyl-2-pyrrolidone (3R)-(-)-1-Benzyl-3-(methylamino)pyrrolidine

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(3R)-Pyrrolidine-3-amine (3R)-pyrrolidin-3-aMine (R)-(+)-3-Aminopyrrolidine 98% 3-amino-R-pyrrolidine (3R)-3-Pyrrolidinamine (3R)-(+)-3-AMINOPYRROLIDINE 98+% (R)-pyrrolidin-3-amine (r)-(R)-3-AMinopyrrolidine (3R)-(+)-AMINOPYRROLIDINE (3R)-()-3-AMINOPYRROLIDINE (3R)-(+)-3-AMINOPYRROLIDINE R-AP (R)-(+)-3-AMINOPYRROLIDINE (R)-3-AMINOPYRROLIDINE PYRROLIDIN-(R)-3-YLAMINE (3R)-(+)-3-Aminopyrrolidine > 3-Pyrrolidinamine, (3R)- CAS:116183-82-5 (R)-(+)-3-Aminopyrrolidine alpha-2-MRAP MYP23 116183-82-5 166183-82-5 C4H10N2 Asymmetric Synthesis Pyrrolidines Heterocyclic Building Blocks Chiral 3-Aminopyrrolidines Amines (Chiral) 3-Aminopyrrolidines Chiral Building Blocks Chiral Building Blocks Heterocyclic Building Blocks Pyrrolidines 3-Aminopyrrolidines Amines (Chiral) Chiral 3-Aminopyrrolidines Pyrrole&Pyrrolidine&Pyrroline API intermediates pharmacetical Chiral Building Blocks Synthetic Organic Chemistry Chiral Compound