4-CHLOROFURO[3,2-C]PYRIDINE
- CAS No.
- 31270-80-1
- Chemical Name:
- 4-CHLOROFURO[3,2-C]PYRIDINE
- Synonyms
- 104328;Compound Fr13857;SALOR-INT L299537-1EA;4-CHLOROFURO[3,2-]PYRIDINE;4-CHLOROFURO[3,2-C]PYRIDINE;1. 4-Chlorofuro[3,2-C]Pyridine;Furo[3,2-c]pyridine, 4-chloro-;4-Chlorofuro[3,2-c]pyridine HCl;4-CHLOROFURO[3,2-C]PYRIDINE 97%;4-Chlorofuro[3,2-c]pyridine, 95+%
- CBNumber:
- CB4758057
- Molecular Formula:
- C7H4ClNO
- Molecular Weight:
- 153.57
- MDL Number:
- MFCD02179768
- MOL File:
- 31270-80-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Chlorofuro[3,2-c]pyridine | 073947 | 1.00g | $50 |
| 4-Chlorofuro[3,2-c]pyridinehydrochloride | 070256 | 5.00g | $80 |
| 4-Chlorofuro[3,2-c]pyridine | 073947 | 5.00g | $180 |
| 4-Chlorofuro[3,2-c]pyridinehydrochloride | 070256 | 10.00g | $160 |
| 4-Chlorofuro[3,2-c]pyridinehydrochloride | 070256 | 25.00g | $357 |
| More product size | |||
| Melting point | 41 °C |
|---|---|
| Boiling point | 243℃ |
| Density | 1.377 |
| Flash point | 101℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | -0.69±0.30(Predicted) |
| color | Orange |
| InChI | InChI=1S/C7H4ClNO/c8-7-5-2-4-10-6(5)1-3-9-7/h1-4H |
| InChIKey | OPFFYLJLHPZSEO-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC2OC=CC1=2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| Hazard Note | Irritant |
| HS Code | 2932190090 |
4-CHLOROFURO[3,2-C]PYRIDINE price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 073947 | 4-Chlorofuro[3,2-c]pyridine | 31270-80-1 | 1.00g | $50 | 2026-05-18 | Buy |
| Matrix Scientific | 070256 | 4-Chlorofuro[3,2-c]pyridinehydrochloride | 31270-80-1 | 5.00g | $80 | 2026-05-18 | Buy |
| Matrix Scientific | 073947 | 4-Chlorofuro[3,2-c]pyridine | 31270-80-1 | 5.00g | $180 | 2026-05-18 | Buy |
| Matrix Scientific | 070256 | 4-Chlorofuro[3,2-c]pyridinehydrochloride | 31270-80-1 | 10.00g | $160 | 2026-05-18 | Buy |
| Matrix Scientific | 070256 | 4-Chlorofuro[3,2-c]pyridinehydrochloride | 31270-80-1 | 25.00g | $357 | 2026-05-18 | Buy |
4-CHLOROFURO[3,2-C]PYRIDINE Chemical Properties,Uses,Production
Definition
ChEBI: 4-Chlorofuro[3,2-c]pyridine is a furopyridine.
Synthesis
26956-43-4
31270-80-1
General procedure for the synthesis of 4-chlorofuranylpyridine from 4,5-dihydro-4-oxofuro[3,2]pyridine: cf. Example 4 Synthesis of 4-chlorofuro[3,2-c]pyridine. 4,5-Dihydro-4-oxofuro[3,2]pyridine (72.2 g, 534 mmol) was added to phosphorochloridic acid (100 mL) preheated to 120 °C with continuous stirring for 30 min. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Ice-cooled water was added to the residue and the pH was adjusted to basic with 8 M aqueous sodium hydroxide, followed by extraction with ethyl acetate. The organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was again removed by distillation under reduced pressure and the resulting crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=30/70) to afford the target product 4-chlorofuranylpyridine (66.1 g, 81% yield). The product was characterized by 1H-NMR (CDCl3): δ 7.13 (1H, dd, J = 2.2, 1.0 Hz), 7.79 (1H, dd, J = 5.8, 1.0 Hz), 8.27 (1H, d, J = 2.2 Hz), 8.32 (1H, d, J = 5.8 Hz).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 1, p. 250 - 254
[2] Journal of Medicinal Chemistry, 1989, vol. 32, # 6, p. 1147 - 1156
[3] Patent: EP2100895, 2009, A1. Location in patent: Page/Page column 44-45
[4] Bulletin de la Societe Chimique de France, 1971, p. 1727 - 1730
[5] Archiv der Pharmazie, 1981, vol. 314, # 2, p. 156 - 162
4-CHLOROFURO[3,2-C]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Synbest Biotech(Hangzhou) Co., Ltd | 86-571-88737065 | sales@synbestech.com | CHINA | 170 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from 4-CHLOROFURO[3,2-C]PYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | 4-chlorofuro[3,2-c]pyridine
31270-80-1
|
US $31.00-76.00 / mg | 99.51% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2026-04-30 | 4-chlorofuro[3,2-c]pyridine
31270-80-1
|
US $31.00-76.00 / mg | 99.51% | 10g | TargetMol Chemicals Inc. | ||
![]() |
2025-11-18 | 4-CHLOROFURO[3,2-C]PYRIDINE
31270-80-1
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
![4-chlorofuro[3,2-c]pyridine pictures](/ProductImageEN1/2025-09/Small/ed0f0ce2-bdaa-4faf-9b90-ea9b47f9c856.png)
- 4-chlorofuro[3,2-c]pyridine
31270-80-1
- US $31.00-76.00 / mg
- 99.51%
- TargetMol Chemicals Inc.
-
![4-chlorofuro[3,2-c]pyridine pictures](/ProductImageEN1/2025-09/Small/8da6b6db-a855-4b48-a067-3ee99a486524.png)
- 4-chlorofuro[3,2-c]pyridine
31270-80-1
- US $31.00-76.00 / mg
- 99.51%
- TargetMol Chemicals Inc.
-
![4-CHLOROFURO[3,2-C]PYRIDINE pictures](/ProductImageEN/2021-10/Small/52461017-fe10-4bf6-a86e-309c475c61a7.jpg)
- 4-CHLOROFURO[3,2-C]PYRIDINE
31270-80-1
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
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