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4-Chlorofuro[3,2-c]pyridine

4-Chlorofuro[3,2-c]pyridine Structure
4-Chlorofuro[3,2-c]pyridine structure
CAS No.
31270-80-1
Chemical Name:
4-Chlorofuro[3,2-c]pyridine
Synonyms
104328;Compound Fr13857;SALOR-INT L299537-1EA;4-CHLOROFURO[3,2-]PYRIDINE;4-Chlorofuro[3,2-c]pyridine;1. 4-Chlorofuro[3,2-C]Pyridine;Furo[3,2-c]pyridine, 4-chloro-;4-Chlorofuro[3,2-c]pyridine HCl;4-CHLOROFURO[3,2-C]PYRIDINE 97%;4-Chlorofuro[3,2-c]pyridine, 95+%
CBNumber:
CB4758057
Molecular Formula:
C7H4ClNO
Molecular Weight:
153.57
MDL Number:
MFCD02179768
MOL File:
31270-80-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:57
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4-Chlorofuro[3,2-c]pyridine Properties

Melting point 41 °C
Boiling point 243℃
Density 1.377
Flash point 101℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka -0.69±0.30(Predicted)
color Orange
InChI InChI=1S/C7H4ClNO/c8-7-5-2-4-10-6(5)1-3-9-7/h1-4H
InChIKey OPFFYLJLHPZSEO-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC2OC=CC1=2

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
Hazard Note  Irritant
HS Code  2932190090

4-Chlorofuro[3,2-c]pyridine price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 269505 4-Chlorofuro[3,2-c]pyridine Asreported 31270-80-1 500mg $382 2026-06-03 Buy
Usbiological 269505 4-Chlorofuro[3,2-c]pyridine Asreported 31270-80-1 1g $552 2026-06-03 Buy
Usbiological 269505 4-Chlorofuro[3,2-c]pyridine Asreported 31270-80-1 2g $785 2026-06-03 Buy
Usbiological 269505 4-Chlorofuro[3,2-c]pyridine Asreported 31270-80-1 5g $1168 2026-06-03 Buy
Usbiological 269505 4-Chlorofuro[3,2-c]pyridine Asreported 31270-80-1 10g $1749 2026-06-03 Buy
Product number Packaging Price Buy
269505 500mg $382 Buy
269505 1g $552 Buy
269505 2g $785 Buy
269505 5g $1168 Buy
269505 10g $1749 Buy

4-Chlorofuro[3,2-c]pyridine Chemical Properties, Uses, Production

Definition

ChEBI: 4-Chlorofuro[3,2-c]pyridine is a furopyridine.

Synthesis

4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE

26956-43-4

4-CHLOROFURO[3,2-C]PYRIDINE

31270-80-1

General procedure for the synthesis of 4-chlorofuranylpyridine from 4,5-dihydro-4-oxofuro[3,2]pyridine: cf. Example 4 Synthesis of 4-chlorofuro[3,2-c]pyridine. 4,5-Dihydro-4-oxofuro[3,2]pyridine (72.2 g, 534 mmol) was added to phosphorochloridic acid (100 mL) preheated to 120 °C with continuous stirring for 30 min. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Ice-cooled water was added to the residue and the pH was adjusted to basic with 8 M aqueous sodium hydroxide, followed by extraction with ethyl acetate. The organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was again removed by distillation under reduced pressure and the resulting crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane=30/70) to afford the target product 4-chlorofuranylpyridine (66.1 g, 81% yield). The product was characterized by 1H-NMR (CDCl3): δ 7.13 (1H, dd, J = 2.2, 1.0 Hz), 7.79 (1H, dd, J = 5.8, 1.0 Hz), 8.27 (1H, d, J = 2.2 Hz), 8.32 (1H, d, J = 5.8 Hz).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 1, p. 250 - 254
[2] Journal of Medicinal Chemistry, 1989, vol. 32, # 6, p. 1147 - 1156
[3] Patent: EP2100895, 2009, A1. Location in patent: Page/Page column 44-45
[4] Bulletin de la Societe Chimique de France, 1971, p. 1727 - 1730
[5] Archiv der Pharmazie, 1981, vol. 314, # 2, p. 156 - 162

4-Chlorofuro[3,2-c]pyridine Preparation Products And Raw materials

Raw materials

4,5-Dihydro-4-oxofuro[3,2-c]pyridine Sodium hydroxide

Preparation Products

3-Bromo-4-chloropyridine 4-methoxyfuro[3,2-c]pyridine-2-carbaldehyde 4-Piperazin-1-yl-furo[3,2-c]pyridine

4-Chlorofuro[3,2-c]pyridine Suppliers

Global Suppliers ( 136)
Supplier Tel Email Country ProdList Advantage
Shanghai TBBMed Co.,Ltd 021-50498136 13564881053 products@tbbmed.com China 180 55
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 21-57721279 18121011378 sales@shydchem.com.cn China 998 56
Shangchem Co., Ltd. +86-21-68182121 China 881 52
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
Supplier Advantage
Shanghai TBBMed Co.,Ltd 55
Accela ChemBio Co.,Ltd. 64
J & K SCIENTIFIC LTD. 76
Beijing Ouhe Technology Co., Ltd 60
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. 56
Shangchem Co., Ltd. 52
Pure Chemistry Scientific Inc. 62
Shanghai Longsheng chemical Co.,Ltd. 59
China DongFan Chemical Co.,LTD 66
Shanghai Ennopharm Co., Ltd. 65

View Latest Price from 4-Chlorofuro[3,2-c]pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-CHLOROFURO[3,2-C]PYRIDINE pictures 2026-08-20 4-CHLOROFURO[3,2-C]PYRIDINE
31270-80-1
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-chlorofuro[3,2-c]pyridine pictures 2026-08-08 4-chlorofuro[3,2-c]pyridine
31270-80-1
 $48.00 99.51% 10g TargetMol Chemicals Inc.
4-chlorofuro[3,2-c]pyridine pictures 2026-08-08 4-chlorofuro[3,2-c]pyridine
31270-80-1
 $48.00 99.51% 10g TargetMol Chemicals Inc.

4-Chlorofuro[3,2-c]pyridine Spectrum

4-CHLOROFURO[3,2-C]PYRIDINE(31270-80-1)1HNMR

31270-80-1 (4-Chlorofuro[3,2-c]pyridine) Related Search:

OTAVA-BB 1199329 5-Bromofuro[2,3-b]pyridine Furo[2,3-b]pyridine Furo[3,2-b]pyridine,4-oxide(9CI) furo[3,2-b]pyridine
Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) 2-b]pyridine Furo[3,2-c]pyridine 4-chlorofuro[3,2-c]pyridine-7-carboxylicacid Furo[3,2-c]pyridine-2-carboxaldehyde (9CI)
Ethanone, 1-furo[2,3-b]pyridin-5-yl- (9CI) 4-Chlorofuro[3,2-c]pyridine 7-Chlorofuro[2,3-c]pyridine 3-(Carboxymethyl)-6-chlorofuro[3,2-b]pyridine-2-carboxylic acid 2-(Carboxymethyl)-6-chlorofuro[3,2-b]pyridine-3-carboxylic acid
AKOS 92637 SALOR-INT L299553-1EA

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SALOR-INT L299537-1EA 4-CHLOROFURO[3,2-]PYRIDINE 4-Chlorofuro[3,2-c]pyridine, 95+% 1. 4-Chlorofuro[3,2-C]Pyridine 4-Chlorofuro[3,2-c]pyridine HCl 4-Chloro-5-azabenzo[b]furan, 4-Chloro-5-aza-1-benzofuran 104328 Furo[3,2-c]pyridine, 4-chloro- 4-CHLOROFURO[3,2-C]PYRIDINE ISO 9001：2015 REACH Compound Fr13857 4-CHLOROFURO[3,2-C]PYRIDINE 97% 4-Chlorofuro[3,2-c]pyridine 31270-80-1 Heterocycles series Halides Fused Ring Systems