1,4-Dibromo-2,5-dimethoxybenzene
- CAS No.
- 2674-34-2
- Chemical Name:
- 1,4-Dibromo-2,5-dimethoxybenzene
- Synonyms
- 2,5-Dimethoxy-1,4-dibromobenzene;2,5-Dibromo-1,4-dimethoxybenzene;1,4-Dimethoxy-2,5-dibromobenzene;1,4-DIBROMO-2,5-DIMETHOXYBENZENE;1,4-Diboromo-2,5-dimethoxybenzene;Benzene,1,4-dibromo-2,5-dimethoxy-;1,4-Dibromo-2,5-dimethoxybenzene>1,4-Dibromo-2,5-dimethoxybenzene,99%;1,4-Dibromo-2,5-dimethoxybenzene 97%;1,4-Dibromo-2,5-dimethoxybenzene, 98+%
- CBNumber:
- CB4778088
- Molecular Formula:
- C8H8Br2O2
- Molecular Weight:
- 295.96
- MDL Number:
- MFCD00025694
- MOL File:
- 2674-34-2.mol
- MSDS File:
- SDS
| Melting point | 144-149 °C (lit.) |
|---|---|
| Boiling point | 290.3±35.0 °C(Predicted) |
| Density | 2,24 g/cm3 |
| refractive index | 1.4947 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Insoluble in water. |
| BRN | 1953103 |
| InChI | InChI=1S/C8H8Br2O2/c1-11-7-3-6(10)8(12-2)4-5(7)9/h3-4H,1-2H3 |
| InChIKey | CHCLRVOURKGRSW-UHFFFAOYSA-N |
| SMILES | C1(Br)=CC(OC)=C(Br)C=C1OC |
| CAS DataBase Reference | 2674-34-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2909303890 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
1,4-Dibromo-2,5-dimethoxybenzene price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 461105 | 1,4-Dibromo-2,5-dimethoxybenzene 97% | 2674-34-2 | 5g | $55 | 2023-06-20 | Buy |
| Sigma-Aldrich | 461105 | 1,4-Dibromo-2,5-dimethoxybenzene 97% | 2674-34-2 | 25g | $155 | 2022-05-15 | Buy |
| TCI Chemical | D3966 | 1,4-Dibromo-2,5-dimethoxybenzene >98.0%(GC) | 2674-34-2 | 5g | $50 | 2026-04-30 | Buy |
| TCI Chemical | D3966 | 1,4-Dibromo-2,5-dimethoxybenzene >98.0%(GC) | 2674-34-2 | 25g | $195 | 2026-04-30 | Buy |
| Biosynth | CAA67434 | 1,4-Dibromo-2,5-dimethoxybenzene | 2674-34-2 | 50g | $590 | 2026-06-04 | Buy |
1,4-Dibromo-2,5-dimethoxybenzene Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
1,4-Dibromo-2,5-dimethoxybenzene was used in the preparation of poly[(9,9-bis(6-(dibromohexyl)-2,7-fluorene))-alt-1,4-(2,5-dimethoxybenzene)], a water-soluble polyfluorene derivative.
Synthesis Reference(s)
The Journal of Organic Chemistry, 63, p. 3764, 1998 DOI: 10.1021/jo9721812
General Description
Crystal structure of 1,4-dibromo-2,5-dimethoxybenzene has been reported to be monoclinic and its asymmetric unit is composed of one-half of the molecule. Lithium diisopropylamide (LDA) mediated metallation of 1,4-dibromo-2,5-dimethoxybenzene has been proposed.
Synthesis
150-78-7
2674-34-2
Example 2: Preparation of 2,5-dibromo-1,4-dimethoxybenzene (2); In a 1 liter round-bottomed flask, a solution of chloroform (50 mL) of bromine (35.2 g, 220 mmol) was added slowly and dropwise to a solution of chloroform (400 mL) of 1,4-dimethoxybenzene (13.8 g, 100 mmol). The reaction mixture was stirred at room temperature for 3 hours before 100 mL of saturated Na2CO3 solution was added to quench the reaction. The organic layer was separated, washed sequentially with water and saturated brine, and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the resulting residue was recrystallized from ethanol to give pure 2,5-dibromo-1,4-dimethoxybenzene (25.8 g, 85% yield). The product was characterized by 1H NMR (CDCl3): δ 7.128 (s, 2H), 3.873 (s, 6H).
References
[1] Tetrahedron, 1999, vol. 55, # 36, p. 11127 - 11142
[2] Tetrahedron Letters, 1998, vol. 39, # 35, p. 6349 - 6350
[3] Organic Process Research and Development, 2016, vol. 20, # 2, p. 284 - 296
[4] Journal of the American Chemical Society, 2003, vol. 125, # 37, p. 11241 - 11248
[5] Journal of Materials Chemistry A, 2017, vol. 5, # 44, p. 22933 - 22938
1,4-Dibromo-2,5-dimethoxybenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Alpha Chemical Co., Ltd. | 0371-55055611 18137792234 | 3957071458@qq.com | China | 9993 | 58 |
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Cuisen Pharmaceutical Technology Co., Ltd. | 13472757003 | yongnan.wang@cendrix.cn | China | 971 | 65 |
View Lastest Price from 1,4-Dibromo-2,5-dimethoxybenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-14 | 1,4-Dibromo-2,5-dimethoxybenzene
2674-34-2
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 1,4-Dibromo-2,5-dimethoxybenzene
2674-34-2
- $1.00
- 99%
- Career Henan Chemical Co
