5-endo-BCN-pentanoic acid
- CAS No.
- 2364591-80-8
- Chemical Name:
- 5-endo-BCN-pentanoic acid
- Synonyms
- endo-BCN-(5-Ava)-OH;endo-BCN-pentanoic acid;5-endo-BCN-pentanoic acid;5-[[[(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethoxy]carbonyl]amino]pentanoic acid;Pentanoic acid, 5-[[[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethoxy]carbonyl]amino]-, rel-
- CBNumber:
- CB48054652
- Molecular Formula:
- C16H23NO4
- Molecular Weight:
- 293.36
- MDL Number:
- MFCD32069515
- MOL File:
- 2364591-80-8.mol
- MSDS File:
- SDS
5-endo-BCN-pentanoic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | PUD59180 | 5-Endo-BCN-pentanoic acid | 2364591-80-8 | 250mg | $1037.5 | 2026-06-04 | Buy |
| Biosynth | PUD59180 | 5-Endo-BCN-pentanoic acid | 2364591-80-8 | 500mg | $1440 | 2026-06-04 | Buy |
| ChemScene | CS-0115899 | 5-endo-BCN-pentanoic acid ≥98% | 2364591-80-8 | 5mg | $54 | 2026-06-04 | Buy |
| ChemScene | CS-0115899 | 5-endo-BCN-pentanoic acid ≥98% | 2364591-80-8 | 10mg | $92 | 2026-06-04 | Buy |
| ChemScene | CS-0115899 | 5-endo-BCN-pentanoic acid ≥98% | 2364591-80-8 | 25mg | $190 | 2026-06-04 | Buy |
5-endo-BCN-pentanoic acid Chemical Properties, Uses, Production
Description
endo-BCN-pentanoic acid is a click chemistry reagent containing a BCN group and a terminal carboxylic acid. The BCN group can react with azide-tagged compounds or biomolecules. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
5-endo-BCN-pentanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 5-endo-BCN-pentanoic acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50
Alkyl-Chain
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
5-endo-BCN-pentanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-endo-BCN-pentanoic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 54996 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
| Nantong Hanfang Biotechnology Co. , Ltd. | hanfangpharma@126.com 18017580634 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Guangdong Wengjiang Chemical Reagent Co.,Ltd. | 0751-2815983 13927872582 | 3008325437@qq.com | China | 9988 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
| Aikon International Limited | 025-58859352 18651614124 | 2881516338@qq.com | China | 9968 | 58 |
View Latest Price from 5-endo-BCN-pentanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | endo-BCN-pentanoic acid
2364591-80-8
|
25mg | >95.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- endo-BCN-pentanoic acid
2364591-80-8
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
