ChemicalBook >> CAS DataBase List >>2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- structure

CAS No.: 2359705-88-5

Chemical Name:: 2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

Synonyms: Lenalidomide-F;3-(4-Fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione;2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-

CBNumber:: CB48205339

Molecular Formula:: C13H11FN2O3

Molecular Weight:: 262.24

MDL Number:

MOL File:: 2359705-88-5.mol

MSDS File:: SDS

Last updated:2026-05-28 03:03:40

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2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- Properties

Boiling point	542.9±50.0 °C(Predicted)
Density	1.461±0.06 g/cm3(Predicted)
form	Solid
pka	10.63±0.40(Predicted)
color	Off-white to gray

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0096964	Lenalidomide-F ≥98%	2359705-88-5	100mg	$52	2026-06-04	Buy
ChemScene	CS-0096964	Lenalidomide-F ≥98%	2359705-88-5	250mg	$99	2026-06-04	Buy
ChemScene	CS-0096964	Lenalidomide-F ≥98%	2359705-88-5	1g	$184	2026-06-04	Buy
ChemScene	CS-0096964	Lenalidomide-F ≥98%	2359705-88-5	5g	$703	2026-06-04	Buy
ChemScene	CS-0096964	Lenalidomide-F ≥98%	2359705-88-5	10g	$1257	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0096964	100mg	$52	Buy
CS-0096964	250mg	$99	Buy
CS-0096964	1g	$184	Buy
CS-0096964	5g	$703	Buy
CS-0096964	10g	$1257	Buy

2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- Chemical Properties, Uses, Production

Uses

Lenalidomide-F is a E3 ligase ligand for LWY713. LWY713 is a PROTAC-class FLT3 degrader (DC50 = 0.64 nM), which selectively induces FLT3 degradation via cereblon and proteasome-dependent pathways[1].

IC 50

Cereblon

References

[1] Liu W et al. Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. Eur J Med Chem. 2023 Nov 19;264:115974. DOI:10.1016/j.ejmech.2023.115974

2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- Suppliers

Global Suppliers ( 35)

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7916	65
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 15250997978	1511893459@qq.com	China	4777	55
Shanghai PharmaPartner Co., Ltd.	19983777532	pharmabridge@163.com	China	500	55
SuZhou Medinoah Co.,LTD.	0512-69561983 13914027025	zhang_q@medinoah.com	China	3925	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1644	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	0531-0531-69900633 19963472814	changyuan20@163.com	China	9938	58
Shanghai Amico Chemicals Co. LTD	微信 18019252918 18019252918	1454668768@qq.com	China	14933	58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD	025-86755008 17751752005	hszhang@bestfluorodrug.com	China	2357	58
Zhengzhou Alpha Chemical Co. LTD	0371-53732842 13383863444	3838551451@qq.com	China	9996	58

Supplier	Advantage
Beijing HwrkChemical Technology Co., Ltd	55
Daicel Chiral Technologies (China)CO.,LTD	65
Nanjing XiZe Biotechnology CO., Ltd.	55
Shanghai PharmaPartner Co., Ltd.	55
SuZhou Medinoah Co.,LTD.	58
Jilin Province Woda Biotechnology Co., Ltd.	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	58
Shanghai Amico Chemicals Co. LTD	58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD	58
Zhengzhou Alpha Chemical Co. LTD	58

2359705-88-5 (2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-) Related Search:

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2,6-Piperidinedione, 3-(4-fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)- Lenalidomide-F 3-(4-Fluoro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione 2359705-88-5