3-Amino-5-bromo-pyridine-2-carbonitrile
- CAS No.
- 573675-27-1
- Chemical Name:
- 3-Amino-5-bromo-pyridine-2-carbonitrile
- Synonyms
- 3-Amino-5-bromopicolinonitrile;3-Amino-5-bromo-2-cyanopyridine;3-Amino-5-bromo-pyridine-2-carbonitrile;2-Pyridinecarbonitrile, 3-amino-5-bromo-;3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE ISO 9001：2015 REACH
- CBNumber:
- CB4822000
- Molecular Formula:
- C6H4BrN3
- Molecular Weight:
- 198.02
- MDL Number:
- MFCD07375025
- MOL File:
- 573675-27-1.mol
- MSDS File:
- SDS
| Boiling point | 376.5±42.0 °C(Predicted) |
|---|---|
| Density | 1.80±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | -1.28±0.10(Predicted) |
| form | solid |
| color | Brown |
| InChI | InChI=1S/C6H4BrN3/c7-4-1-5(9)6(2-8)10-3-4/h1,3H,9H2 |
| InChIKey | WDKOOTHLXCMQGH-UHFFFAOYSA-N |
| SMILES | C1(C#N)=NC=C(Br)C=C1N |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301+P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral |
3-Amino-5-bromo-pyridine-2-carbonitrile price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | ADE000135 | 3-Amino-5-bromopicolinonitrile Aldrich | 573675-27-1 | 1g | $870 | 2026-04-30 | Buy |
| Apolloscientific | OR959411 | 3-Amino-5-bromopyridine-2-carbonitrile 99% | 573675-27-1 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR959411 | 3-Amino-5-bromopyridine-2-carbonitrile 99% | 573675-27-1 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR959411 | 3-Amino-5-bromopyridine-2-carbonitrile 99% | 573675-27-1 | 5g | $96 | 2026-06-04 | Buy |
| Apolloscientific | OR959411 | 3-Amino-5-bromopyridine-2-carbonitrile 99% | 573675-27-1 | 25g | $468 | 2026-06-04 | Buy |
3-Amino-5-bromo-pyridine-2-carbonitrile Chemical Properties, Uses, Production
Synthesis
573675-25-9
573675-27-1
Step 1: 5-bromo-2-cyano-3-nitropyridine (K1, 5 g, 21.9 mmol) was dissolved in cooled concentrated hydrochloric acid (30 mL), and tin chloride dihydrate (SnCl2-2H2O, 24.7 g, 109.5 mmol) was added in batches. After the addition was completed, the reaction mixture was stirred at room temperature overnight. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent ratio PE:EA = 3:1) to confirm the completion of the reaction. Subsequently, the mixture was alkalized with aqueous sodium carbonate and extracted with ethyl acetate. The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated and the resulting residue was purified by column chromatography (eluent ratio PE:EA = 20:1 to 5:1) to afford 3-amino-5-bromopyridine-2-carbonitrile (K2, 1.9 g). Mass spectrometry (MS) analysis showed molecular ion peaks m/e = 198 and 200 (M + 1) for K2.
References
[1] Patent: WO2005/42498, 2005, A2. Location in patent: Page/Page column 44
[2] Patent: WO2011/51540, 2011, A1. Location in patent: Page/Page column 74
[3] Patent: WO2016/118404, 2016, A1. Location in patent: Page/Page column 46; 47
3-Amino-5-bromo-pyridine-2-carbonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Huzhou Huanyu Biotechnology Co. , Ltd. | 18757211187 18994340517 | 709951195@qq.com | China | 94 | 58 |
| Shaoyuan Technology (Shanghai) Co., Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 9985 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from 3-Amino-5-bromo-pyridine-2-carbonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
573675-27-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | 3-Amino-5-Bromopicolinonitrile
573675-27-1
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-AMINO-5-BROMO-PYRIDINE-2-CARBONITRILE
573675-27-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Amino-5-Bromopicolinonitrile
573675-27-1
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
