Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-
- CAS No.
- 1185410-60-9
- Chemical Name:
- Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-
- Synonyms
- LRH-1 Antagonist;LRH1 Inhibitor 3;LRH-1-Inhibitor-3;LRH-1 Inhibitor-3;LRH 1 Inhibitor 3;LRH1 Inhibitor3,LRH 1 Inhibitor 3;1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one;1-[3′-[1-[2-(4-Morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1′-biphenyl]-3-yl]ethanone;Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-
- CBNumber:
- CB48348876
- Molecular Formula:
- C23H25N3O2
- Molecular Weight:
- 375.46
- MDL Number:
- MFCD30140203
- MOL File:
- 1185410-60-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | WGK 2 |
| Storage Class | 11 - Combustible Solids |
Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | KXB41060 | 1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one | 1185410-60-9 | 50mg | $1848 | 2026-06-04 | Buy |
| Biosynth | KXB41060 | 1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one | 1185410-60-9 | 0.5g | $6047.5 | 2026-06-04 | Buy |
| ChemScene | CS-0065100 | LRH-1 Inhibitor-3 98.81% | 1185410-60-9 | 5mg | $233 | 2026-06-04 | Buy |
| ChemScene | CS-0065100 | LRH-1 Inhibitor-3 98.81% | 1185410-60-9 | 10mg | $350 | 2026-06-04 | Buy |
| ChemScene | CS-0065100 | LRH-1 Inhibitor-3 98.81% | 1185410-60-9 | 25mg | $700 | 2026-06-04 | Buy |
Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Chemical Properties, Uses, Production
Description
LRH-1 Inhibitor-3 is the first small molecule antagonist of LRH-1 activity.
Uses
LRH-1 Inhibitor-3 is a small molecule that inhibits LRH-1 transcriptional activity, thereby decreasing the expression of target genes associated with cell growth and proliferation. LRH-1 Inhibitor-3 has shown potential in reducing cancer cell proliferation in human pancreatic, colon, and breast adenocarcinoma cell lines. LRH-1 Inhibitor-3 serves as a molecular probe for investigating the role of LRH-1 in various malignancies.
Definition
ChEBI: 1-(3'-{1-[2-(morpholin-4-yl)ethyl]pyrazol-3-yl}[1,1'-biphenyl]-3-yl)ethan-1-one is a member of the class of pyrazoles 1-[2-(morpholin-4-yl)ethyl]pyrazole carrying an additional 3'-acetyl-1,1'-biphenyl-3-yl group at position 3. An antagonist at LRH-1. It has a role as a LRH-1 antagonist. It is a member of pyrazoles, a member of morpholines, a methyl ketone, a ring assembly and an aromatic ketone.
References
[1] Structure-based discovery of antagonists of nuclear receptor LRH-1 DOI:10.1074/jbc.M112.411686
Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Preparation Products And Raw materials
Raw materials
Preparation Products
Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 7983 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | QQ1259737804 15268198094 | sales@torreybio.com | China | 4128 | 58 |
| Guangzhou Aiyu Technology Co.,Ltd | 18588406486 | courage.you@foxmail.com | China | 211 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Aikon International Limited | 025-58859352 18651614124 | 2881516338@qq.com | China | 9968 | 58 |
| Henan Inokai New Materials Co., Ltd | 15090072163 | 3921118937@qq.com | China | 2676 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
| Guangzhou Ruidi Biotechnology Co., Ltd. | 020-82099279 18988941402 | sales@ubiochem.com | China | 9998 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
View Latest Price from Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-09 | LRH-1 Inhibitor-3
1185410-60-9
|
$533.00-987.00 | 10g | TargetMol Chemicals Inc. |
-

- LRH-1 Inhibitor-3
1185410-60-9
- $533.00-987.00
- TargetMol Chemicals Inc.
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