ChemicalBook >> CAS DataBase List >>Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-

Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-

CAS No.
1185410-60-9
Chemical Name:
Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-
Synonyms
LRH-1 Antagonist;LRH1 Inhibitor 3;LRH-1-Inhibitor-3;LRH-1 Inhibitor-3;LRH 1 Inhibitor 3;LRH1 Inhibitor3,LRH 1 Inhibitor 3;1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one;1-[3′-[1-[2-(4-Morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1′-biphenyl]-3-yl]ethanone;Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]-
CBNumber:
CB48348876
Molecular Formula:
C23H25N3O2
Molecular Weight:
375.46
MDL Number:
MFCD30140203
MOL File:
1185410-60-9.mol
MSDS File:
SDS
Last updated:2026-05-28 03:37:09

Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Properties

Boiling point 578.4±50.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 100mg/mL
pka 6+-.0.10(Predicted)
form solid
color pale yellow
UNSPSC Code 41106200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338
WGK Germany  WGK 2
Storage Class 11 - Combustible Solids

Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth KXB41060 1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one 1185410-60-9 50mg $1848 2026-06-04 Buy
Biosynth KXB41060 1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one 1185410-60-9 0.5g $6047.5 2026-06-04 Buy
ChemScene CS-0065100 LRH-1 Inhibitor-3 98.81% 1185410-60-9 5mg $233 2026-06-04 Buy
ChemScene CS-0065100 LRH-1 Inhibitor-3 98.81% 1185410-60-9 10mg $350 2026-06-04 Buy
ChemScene CS-0065100 LRH-1 Inhibitor-3 98.81% 1185410-60-9 25mg $700 2026-06-04 Buy
Product number Packaging Price Buy
KXB41060 50mg $1848 Buy
KXB41060 0.5g $6047.5 Buy
CS-0065100 5mg $233 Buy
CS-0065100 10mg $350 Buy
CS-0065100 25mg $700 Buy

Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Chemical Properties, Uses, Production

Description

LRH-1 Inhibitor-3 is the first small molecule antagonist of LRH-1 activity.

Uses

LRH-1 Inhibitor-3 is a small molecule that inhibits LRH-1 transcriptional activity, thereby decreasing the expression of target genes associated with cell growth and proliferation. LRH-1 Inhibitor-3 has shown potential in reducing cancer cell proliferation in human pancreatic, colon, and breast adenocarcinoma cell lines. LRH-1 Inhibitor-3 serves as a molecular probe for investigating the role of LRH-1 in various malignancies.

Definition

ChEBI: 1-(3'-{1-[2-(morpholin-4-yl)ethyl]pyrazol-3-yl}[1,1'-biphenyl]-3-yl)ethan-1-one is a member of the class of pyrazoles 1-[2-(morpholin-4-yl)ethyl]pyrazole carrying an additional 3'-acetyl-1,1'-biphenyl-3-yl group at position 3. An antagonist at LRH-1. It has a role as a LRH-1 antagonist. It is a member of pyrazoles, a member of morpholines, a methyl ketone, a ring assembly and an aromatic ketone.

References

[1] Structure-based discovery of antagonists of nuclear receptor LRH-1 DOI:10.1074/jbc.M112.411686

Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- Suppliers

Global Suppliers ( 12)
Supplier Tel Email Country ProdList Advantage
Shanghai Haozhixiang Biotechnology Co., Ltd 526763801 13301653310 526763801@qq.com China 7983 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Hangzhou Taorui Biotechnology Co., Ltd QQ1259737804 15268198094 sales@torreybio.com China 4128 58
Guangzhou Aiyu Technology Co.,Ltd 18588406486 courage.you@foxmail.com China 211 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Aikon International Limited 025-58859352 18651614124 2881516338@qq.com China 9968 58
Henan Inokai New Materials Co., Ltd 15090072163 3921118937@qq.com China 2676 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Guangzhou Ruidi Biotechnology Co., Ltd. 020-82099279 18988941402 sales@ubiochem.com China 9998 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LRH-1 Inhibitor-3 pictures 2026-05-09 LRH-1 Inhibitor-3
1185410-60-9
$533.00-987.00 10g TargetMol Chemicals Inc.
Ethanone, 1-[3'-[1-[2-(4-morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]- LRH 1 Inhibitor 3 LRH1 Inhibitor 3 LRH-1 Inhibitor-3 LRH-1-Inhibitor-3 LRH1 Inhibitor3,LRH 1 Inhibitor 3 LRH-1 Antagonist 1-[3-(3-{1-[2-(Morpholin-4-yl)ethyl]-1H-pyrazol-3-yl}phenyl)phenyl]ethan-1-one 1-[3′-[1-[2-(4-Morpholinyl)ethyl]-1H-pyrazol-3-yl][1,1′-biphenyl]-3-yl]ethanone 1185410-60-9