6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine
![6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine Structure](CAS/GIF/181468-88-2.gif)
- CAS No.
- 181468-88-2
- Chemical Name:
- 6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine
- Synonyms
- PD 160170;6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine;8-Quinolinamine, 6-[[2-(1-methylethyl)phenyl]sulfonyl]-5-nitro-
- CBNumber:
- CB4842172
- Molecular Formula:
- C18H17N3O4S
- Molecular Weight:
- 371.41
- MDL Number:
- MFCD00945695
- MOL File:
- 181468-88-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 646.6±55.0 °C(Predicted) |
|---|---|
| Density | 1.379±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble to 100 mM in DMSO |
| form | Powder |
| pka | -1.16±0.12(Predicted) |
| FDA UNII | GQ34MN6NT8 |
6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 256185 | PD 160170 Asreported | 181468-88-2 | 10mg | $438 | 2026-06-03 | Buy |
| Usbiological | 256185 | PD 160170 Asreported | 181468-88-2 | 50mg | $1160 | 2026-06-03 | Buy |
| aablocks | AA0022TU | 6-((2-Isopropylphenyl)sulfonyl)-5-nitroquinolin-8-amine ≥98% | 181468-88-2 | 10mg | $363 | 2026-05-28 | Buy |
| aablocks | AA0022TU | 6-((2-Isopropylphenyl)sulfonyl)-5-nitroquinolin-8-amine ≥98% | 181468-88-2 | 25mg | $650 | 2026-05-28 | Buy |
| aablocks | AA0022TU | 6-((2-Isopropylphenyl)sulfonyl)-5-nitroquinolin-8-amine ≥98% | 181468-88-2 | 50mg | $1163 | 2026-05-28 | Buy |
6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine Chemical Properties, Uses, Production
Uses
PD 160170 is a compound developed to inhibit low-risk myelodysplastic syndrome-associated anemia with activities that promote red blood cell transfusion independence and increase hemoglobin.
Definition
ChEBI: 5-nitro-6-(2-propan-2-ylphenyl)sulfonyl-8-quinolinamine is a nitro compound and a member of quinolines.
Biological Activity
Potent, selective non-peptidic neuropeptide Y 1 receptor antagonist (K i = 48 nM); selective over Y 2 and Y 5 receptors (K i > 10 μ M). Antagonizes NPY-mediated inhibition of cAMP accumulation in SK-N-MC cells (IC 50 = 8.2 nM).
References
[1] 8-Amino-5-nitro-6-phenoxyquinolines: potential non-peptidic neuropeptide Y receptor ligands
6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine Preparation Products And Raw materials
Raw materials
Preparation Products
6-[[2-(1-Methylethyl)phenyl]]sulfonyl-5-nitro-8-quinolinamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| InvivoChem | 13549236410 | sales@invivochem.cn | China | 6745 | 58 |
| Shanxi Nuocheng Biotechnology Co., Ltd | 17835231871 | 572710841@qq.com | China | 7939 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 69 |
| BOC Sciences | 65 |
| EMMX Biotechnology LLC | 60 |
| TargetMol Chemicals Inc. | 58 |
| InvivoChem | 58 |
| InvivoChem | 58 |
| Shanxi Nuocheng Biotechnology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
