5-Methoxy-pyridin-3-ylamine
- CAS No.
- 64436-92-6
- Chemical Name:
- 5-Methoxy-pyridin-3-ylamine
- Synonyms
- 5-Methoxypyridin-3-amine;5-Me;5-Methoxy-pyridin-3-;5-Methoxy-3-pyridinamine;3-Amino-5-methoxypyridine;5-Methoxy-3-aminopyridine;3-Pyridinamine, 5-methoxy-;5-Methoxy-pyridin-3-ylamine;5-Methoxy-pyridin-3-amine ,98%;5-Fluoro-2,6-dimethyl-4-pyrimidinamine
- CBNumber:
- CB4875561
- Molecular Formula:
- C6H8N2O
- Molecular Weight:
- 124.14
- MDL Number:
- MFCD09701369
- MOL File:
- 64436-92-6.mol
- MSDS File:
- SDS
| Melting point | 64-65 °C(Solv: benzene (71-43-2)) |
|---|---|
| Boiling point | 166-168 °C(Press: 15 Torr) |
| Density | 1.139±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 5.80±0.10(Predicted) |
| Appearance | Brown to reddish brown Solid |
| InChI | InChI=1S/C6H8N2O/c1-9-6-2-5(7)3-8-4-6/h2-4H,7H2,1H3 |
| InChIKey | CTQPCFFQBYXOAJ-UHFFFAOYSA-N |
| SMILES | C1=NC=C(OC)C=C1N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 41 |
| Safety Statements | 26-39 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
5-Methoxy-pyridin-3-ylamine price More Price(49)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 260418 | 3-Amino-5-methoxypyridine Asreported | 64436-92-6 | 1g | $425 | 2026-06-03 | Buy |
| Usbiological | 260418 | 3-Amino-5-methoxypyridine Asreported | 64436-92-6 | 2g | $593 | 2026-06-03 | Buy |
| Usbiological | 260418 | 3-Amino-5-methoxypyridine Asreported | 64436-92-6 | 5g | $829 | 2026-06-03 | Buy |
| Usbiological | 260418 | 3-Amino-5-methoxypyridine Asreported | 64436-92-6 | 10g | $1137 | 2026-06-03 | Buy |
| Usbiological | 260418 | 3-Amino-5-methoxypyridine Asreported | 64436-92-6 | 25g | $1798 | 2026-06-03 | Buy |
5-Methoxy-pyridin-3-ylamine Chemical Properties, Uses, Production
Synthesis
50720-12-2
64436-92-6
General procedure for the synthesis of 3-bromo-5-methoxypyridine from 3-bromo-5-methoxypyridine: 3-bromo-5-methoxypyridine (500 mg, 2.66 mmol), ammonium hydroxide (15 mL), and cobalt sulfate pentahydrate (33 mg, 0.13 mmol) were placed in a hermetically sealed tube and heated in a microwave reactor for 20 hours at 140 °C. After completion of the reaction, the reaction mixture was cooled to room temperature and the crude product was subjected to liquid-liquid separation between ethyl acetate and water. The organic layer was washed sequentially with water (3 times) and saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 84 mg of solid product in 25% yield. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.72 (d, J = 5.4 Hz, 2H), 6.51 (t, J = 2.4 Hz, 1H), 3.79 (s, 3H) ppm; HPLC-MS: m/z 125.0.
References
[1] Organic Process Research and Development, 2012, vol. 16, # 5, p. 788 - 797
[2] Advanced Synthesis and Catalysis, 2013, vol. 355, # 4, p. 627 - 631
[3] European Journal of Medicinal Chemistry, 2015, vol. 106, p. 50 - 59
[4] Patent: US2007/167497, 2007, A1. Location in patent: Page/Page column 26
[5] Patent: US2014/336182, 2014, A1. Location in patent: Paragraph 0315
5-Methoxy-pyridin-3-ylamine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44566 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 15343 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
View Latest Price from 5-Methoxy-pyridin-3-ylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 3-Amino-5-methoxypyridine
64436-92-6
|
$1.00 | 1kg | 95%-99% | Career Henan Chemical Co |
-
- 3-Amino-5-methoxypyridine
64436-92-6
- $1.00
- 95%-99%
- Career Henan Chemical Co
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