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ChemicalBook >> CAS DataBase List >>N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester Structure
N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester structure
CAS No.
21959-36-4
Chemical Name:
N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester
Synonyms
diiodophenyl)propanoate;5-diiodo-L-tyrosine ethyl ester;N-ACETYL DIIODOTYROSINE ETHYL ESTER;3,5-Diiodo-N-acetyltyrosine ethyleste;Ethyl N-acetyl-3,5-diiodo-L-tyrosinate;N-acetyl-3,5-diiodotyrosine ethyl ester;N-Acetyl-3,5-dijod-L-tyrosin-aethylester;N-ACETYL-3,5-DIIODE-L-TYROSINE ETHYL ESTER;N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester;L-Tyrosine, N-acetyl-3,5-diiodo-, ethyl ester
CBNumber:
CB4947707
Molecular Formula:
C13H15I2NO4
Molecular Weight:
503.07
MDL Number:
MFCD00136808
MOL File:
21959-36-4.mol
MSDS File:
SDS
Last updated:2026-06-03 18:11:14
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N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester Properties

Boiling point 491.8±45.0 °C(Predicted)
Density 1.956±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 6.90±0.25(Predicted)
Appearance White to off-white Solid
optical activity Consistent with structure
InChI InChI=1S/C13H15I2NO4/c1-3-20-13(19)11(16-7(2)17)6-8-4-9(14)12(18)10(15)5-8/h4-5,11,18H,3,6H2,1-2H3,(H,16,17)/t11-/m0/s1
InChIKey BPKHOPGWGZAARI-NSHDSACASA-N
SMILES C(OCC)(=O)[C@H](CC1=CC(I)=C(O)C(I)=C1)NC(C)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S790176 N-ACETYL-3,5-DIIODO-L-TYROSINE ETHYL ESTER AldrichCPR 21959-36-4 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S790176 N-ACETYL-3,5-DIIODO-L-TYROSINE ETHYL ESTER AldrichCPR 21959-36-4 25MG $179 2024-03-01 Buy
Synthonix E92088 (S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate 95+% 21959-36-4 1g $71 2026-05-06 Buy
Synthonix E92088 (S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate 95+% 21959-36-4 5g $80 2026-05-06 Buy
Synthonix E92088 (S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate 95+% 21959-36-4 25g $210 2026-05-06 Buy
Product number Packaging Price Buy
S790176 1 unit $197 Buy
S790176 25MG $179 Buy
E92088 1g $71 Buy
E92088 5g $80 Buy
E92088 25g $210 Buy

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester Chemical Properties, Uses, Production

Uses

(S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate is a useful research chemical compound.

Chemical Properties

Crystallization. Melting point 150-152℃.

Synthesis

60 g of N-acetyl-3,5-diiodo-L-tyrosine and 900 mL of absolute ethanol were added to a 2 L reaction flask and stirred at room temperature for 30 minutes, then 5.8 mL of thionyl chloride was added, and then the temperature was raised to 50 ℃. The reaction was stirred for 1 hour, and after the reaction was completed, the mixture was concentrated to dryness under reduced pressure. The crude product was dissolved in 500 mL of dichloromethane and washed twice with 300 mL of saturated sodium hydrogen carbonate solution. The crude product was filtered off with suction, then beaten in 100 mL dichloromethane, and concentrated to dryness. The organic phase was dried over anhydrous sodium sulfate and under reduced pressure. The mixture was washed with 10 mL of dichloromethane, and the obtained cake was dried under vacuum at 40 ℃ for 5 hours to obtain 56.1 g of a white powdery solid N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester. The yield was 88.3%, and the purity was 98.52%.

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester synthesis

64-17-5
1027-28-7
21959-36-4
Synthesis of N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester from Ethanol and N-Acetyl-3,5-diiodo-L-tyrosine

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester Preparation Products And Raw materials

Raw materials

Boc-D-Tyr-OH Para toluene 3,5-Diiodo-DL-tyrosine Iodine monochloride N-Acetyl-3,5-diiodo-L-tyrosine
L-Tyrosine Ethanol 3,5-Diiodo-L-tyrosine dihydrate

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Preparation Products

Levothyroxine Sodium Impurity 16 Ethyl 2-(acetylamino)-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoate

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester Suppliers

Global Suppliers ( 134)
Supplier Tel Email Country ProdList Advantage
Haimen DsHare Pharmaceutical Technology Co., Ltd. +86-0513-68050135 13962878782 zhuwdsh@126.com China 155 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
Hunan Furui Biopharma Technology Co., Ltd. 15901640172，19275032510 15901640172 sales03@hn-furui.com China 380 55
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10628 60
Shifang ShengYuan Technology Co., Ltd. 0838-6510595 13402890778 15102836436 1120021438@qq.com China 132 56
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 1999 58
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Supplier Advantage
Haimen DsHare Pharmaceutical Technology Co., Ltd. 58
Shanghai Hanhong Scientific Co.,Ltd. 64
Syntechem Co.,Ltd 57
Tianjin heowns Biochemical Technology Co., Ltd. 57
Shanghai Sphchem Co., Ltd. 55
Hunan Furui Biopharma Technology Co., Ltd. 55
HBCChem, Inc. 60
Shifang ShengYuan Technology Co., Ltd. 56
HangZhou YuHao Chemical Technology Co., Ltd. 58
Shanghai YuLue Chemical Co., Ltd. 55

View Latest Price from N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester pictures 2026-06-03 N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester
21959-36-4
 $1.50 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
diiodophenyl)propanoate pictures 2021-07-13 diiodophenyl)propanoate
21959-36-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
diiodophenyl)propanoate pictures 2021-07-10 diiodophenyl)propanoate
21959-36-4
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester Spectrum

N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester(21959-36-4)1HNMR

21959-36-4 (N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester) Related Search:

L(+)-Arginine Ethyl L-tyrosinate 3,5-Diiodo-L-tyrosine dihydrate Ethyl 2-(acetylamino)-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]propanoate N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester
N-Acetyl-3,5-diiodo-L-tyrosine

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N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester N-ACETYL-3,5-DIIODE-L-TYROSINE ETHYL ESTER (S)-Ethyl 2-acetaMido-3-(4-hydroxy-3,5-diiodophenyl)propanoate ethyl 2-acetaMido-3-(4-hydroxy-3,5-diiodophenyl)propanoate Ethyl N-acetyl-3,5-diiodo-L-tyrosinate ethyl (2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate N-ACETYL DIIODOTYROSINE ETHYL ESTER 5-diiodo-L-tyrosine ethyl ester N-Acetyl-3,5-dijod-L-tyrosin-aethylester 3,5-Diiodo-N-acetyltyrosine ethyleste Tyrosine,N-acetyl-3,5-diiodo-, ethyl ester, L- (8CI) (2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid ethyl ester L-Tyrosine, N-acetyl-3,5-diiodo-, ethyl ester N-Acetyl-3,5-diiodo-L-tyrosine ethyl ester USP/EP/BP diiodophenyl)propanoate Ethyl (S)-2-Acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate N-acetyl-3,5-diiodotyrosine ethyl ester (S)-Ethyl 2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanoate - [E92088] 21959-36-4 1959-36-4 C13H15I2NO4 000-111