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2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER structure

CAS No.: 70146-78-0

Chemical Name:: 2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER

Synonyms: Diethyl-(4-brombenzyl)malonat;diethyl 2-(4-broMobenzyl)Malonate;2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER;diethyl 2-[(4-bromophenyl)methyl]propanedioate;1,3-diethyl 2-[(4-bromophenyl)methyl]propanedioate;Propanedioic acid, 2-[(4-bromophenyl)methyl]-, 1,3-diethyl ester

CBNumber:: CB51009775

Molecular Formula:: C14H17BrO4

Molecular Weight:: 329.19

MDL Number:

MOL File:: 70146-78-0.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:48

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2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Properties

Boiling point	193-198 °C(Press: 14 Torr)
Density	1.344±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	12.35±0.59(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301+H311+H331-H315-H319
Precautionary statements	P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	HCH0117068	2-(4-BROMO-BENZYL)MALONIC ACID DIETHYL ESTER 95.00%	70146-78-0	5MG	$499.58	2021-12-16	Buy
Chemenu	CM254636	Diethyl2-(4-bromobenzyl)malonate 95+%	70146-78-0	5g	$982	2021-12-16	Buy
Crysdot	CD12041442	Diethyl2-(4-bromobenzyl)malonate 97%	70146-78-0	5g	$1040	2021-12-16	Buy
Alichem	70146780	Diethyl2-(4-bromobenzyl)malonate	70146-78-0	5g	$1261.75	2021-12-16	Buy
Chemenu	CM254636	Diethyl2-(4-bromobenzyl)malonate 95+%	70146-78-0	10g	$1636	2021-12-16	Buy

Product number	Packaging	Price	Buy
HCH0117068	5MG	$499.58	Buy
CM254636	5g	$982	Buy
CD12041442	5g	$1040	Buy
70146780	5g	$1261.75	Buy
CM254636	10g	$1636	Buy

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Chemical Properties,Uses,Production

Synthesis

589-15-1

105-53-3

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER

70146-78-0

Sodium metal (5.82 g, 0.25 mol) was added to ethanol (240 mL) and stirred until the sodium was completely dissolved. 1-Bromo-4-bromomethylbenzene (37.35 g, 0.15 mol) and diethyl malonate (78 g, 0.49 mol) were then added. The reaction mixture was slowly heated to reflux overnight. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in distilled water and extracted with ether. The organic layer was washed sequentially with 0.5 N aqueous hydrochloric acid and saturated brine, dried over anhydrous sodium sulfate and concentrated to give diethyl 2-(4-bromobenzyl)malonate (40 g, 85% yield).

References

[1] Patent: WO2010/105179, 2010, A2. Location in patent: Page/Page column 76
[2] Journal of Organic Chemistry, 1984, vol. 49, # 22, p. 4226 - 4237
[3] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994, vol. 30, # 8, p. 905 - 915
[4] Khimiya Geterotsiklicheskikh Soedinenii, 1993, # 8, p. 1052 - 1062
[5] Tetrahedron Asymmetry, 2001, vol. 12, # 4, p. 585 - 596

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Preparation Products And Raw materials

Raw materials

4-Bromobenzyl bromide Diethyl malonate

Preparation Products

6-Bromoindanone 6-BROMO-2,3-DIHYDRO-1H-INDEN-1-OL

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER Suppliers

Global( 29)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; +8619817745290	bd@blocksynth.com	China	5661	58
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	sales@aochuangchem.com	China	9297	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58
Compound Net Biotechnology Inc.	+8615303909093	sales@compound-net.com	China	2914	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58
BeiJing Hwrk Chemicals Limted	0757-86329057 18934348241	sales4.gd@hwrkchemical.com	China	14063	55
Shanghai Topbiochem Technology Co., Ltd	021-58170097	info@topbiochem.com	China	9497	58
AAB-PHARMA LIMITED	025-66800956 18800000000	sales@njdmchem.com	China	4200	50
Beijing YiboYuntian Technology Co., Ltd.	13811826434	lichen13811826434@126.com	China	655	58

Supplier	Advantage
Career Henan Chemica Co	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Henan Aochuang Chemical Co.,Ltd.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Compound Net Biotechnology Inc.	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	58
BeiJing Hwrk Chemicals Limted	55
Shanghai Topbiochem Technology Co., Ltd	58
AAB-PHARMA LIMITED	50
Beijing YiboYuntian Technology Co., Ltd.	58

View Lastest Price from 2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-04-04	2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER 70146-78-0	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER
70146-78-0
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

70146-78-0(2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER)Related Search:

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2-(4-BROMO-BENZYL)-MALONIC ACID DIETHYL ESTER diethyl 2-(4-broMobenzyl)Malonate Diethyl-(4-brombenzyl)malonat Propanedioic acid, 2-[(4-bromophenyl)methyl]-, 1,3-diethyl ester diethyl 2-[(4-bromophenyl)methyl]propanedioate 1,3-diethyl 2-[(4-bromophenyl)methyl]propanedioate 70146-78-0