3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid
- CAS No.
- 175277-11-9
- Chemical Name:
- 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid
- Synonyms
- BUTTPARK 52\11-22;TIMTEC-BB SBB010222;3-(tert-Butyl)-5-carboxy-1-methyl-1H-pyrazole;3-TERT-BUTYL-1-METHYLPYRAZOLE-5-CARBOXYLIC ACID;5-tert-butyl-2-methylpyrazole-3-carboxylic acid;3-(T-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID;5-tert-Butyl-2-methyl-2H-pyrazol-3-carboxylic acid;3-(tert-Butyl)-1-methyl-1H-pyrazole-carboxylic acid;5-TERT-BUTYL-2-METHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID;3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid
- CBNumber:
- CB5108464
- Molecular Formula:
- C9H14N2O2
- Molecular Weight:
- 182.22
- MDL Number:
- MFCD00173812
- MOL File:
- 175277-11-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 151 °C |
|---|---|
| Boiling point | 317.7±30.0 °C(Predicted) |
| Density | 1.13 |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.15±0.25(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 175277-11-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36/37/39-37/39 |
| HazardClass | IRRITANT |
| HS Code | 2933199090 |
3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR1280 | 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid 95% | 175277-11-9 | 1g | $43 | 2026-06-04 | Buy |
| Apolloscientific | OR1280 | 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid 95% | 175277-11-9 | 5g | $153 | 2026-06-04 | Buy |
| Apolloscientific | OR1280 | 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid 95% | 175277-11-9 | 10g | $263 | 2026-06-04 | Buy |
| Apolloscientific | OR1280 | 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid 95% | 175277-11-9 | 50g | $814 | 2026-06-04 | Buy |
| Synthonix | B9794 | 3-tert-Butyl-1-methylpyrazole-5-carboxylic Acid 90+% | 175277-11-9 | 250mg | $51 | 2026-05-06 | Buy |
3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid Chemical Properties, Uses, Production
Synthesis
133261-10-6
175277-11-9
General procedure for the synthesis of 1-methyl-3-tert-butylpyrazole-5-carboxylic acid from ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate: 2 M aqueous sodium hydroxide solution (100 mL) was added to ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate (185 mmol), and the reaction mixture was heated and refluxed for 2.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with 100 mL of water and the pH was adjusted to acidic (about pH 2) with 30% aqueous hydrochloric acid. The precipitated solid was collected by filtration, washed with water and dried at 60 °C for 24 h to afford 1-methyl-3-tert-butylpyrazole-5-carboxylic acid as an off-white solid (27.1 g, 80% yield). [0211] 1H NMR (400 MHz, DMSO-d6) δ: 13.19 (broad peak, 1H), 6.66 (single peak, 1H), 3.99 (single peak, 3H), 1.23 (single peak, 9H). Mass spectrum (m/z): 183 (M + H).
References
[1] Journal of Organic Chemistry, 1997, vol. 62, # 17, p. 5908 - 5919
[2] Patent: WO2009/71706, 2009, A1. Location in patent: Page/Page column 43-44
[3] Patent: US2011/218197, 2011, A1. Location in patent: Page/Page column 44
[4] Patent: US2012/202856, 2012, A1. Location in patent: Page/Page column 22
3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1401 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Record Tech (Shanghai) Co., LTD | 13761627472 | 183009664@qq.com | China | 659 | 62 |
| Acorn PharmaTech Co., Ltd. | 025-58395930 | sales@acornpharma.com | China | 982 | 60 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
View Latest Price from 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-10 | 3-tert-Butyl-1-methylpyrazole-5-carboxylic acid
175277-11-9
|
1KG | 98%; 99% | 500g;1kg； 25kg | Career Henan Chemical Co |
-
- 3-tert-Butyl-1-methylpyrazole-5-carboxylic acid
175277-11-9
- $0.01
- 98%; 99%
- Career Henan Chemical Co
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