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1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid Structure
1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid structure
CAS No.
100957-85-5
Chemical Name:
1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid
Synonyms
BUTTPARK 153\57-04;SORT-PGRN interaction inhibitor 1;2-benzyl-5-tert-butylpyrazole-3-carboxylic acid;2-Benzyl-5-tert-butyl-2H-pyrazole-3-carboxylic acid;1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid;1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid, 95+%;1H-Pyrazole-5-carboxylic acid, 3-(1,1-dimethylethyl)-1-(phenylmethyl)-;inhibit,PPI,Inhibitor,sortilin,SORTPGRN interaction inhibitor 1,progranulin,PGRN,Neurotensin Receptor,SORT-PGRN interaction inhibitor 1,SORT PGRN interaction inhibitor 1
CBNumber:
CB8739425
Molecular Formula:
C15H18N2O2
Molecular Weight:
258.32
MDL Number:
MFCD02090479
MOL File:
100957-85-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:55:52
Request For Quotation

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid Properties

Melting point 126 °C
Boiling point 438.4±40.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
storage temp. 2-8°C
form Solid
pka 3.69±0.36(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-36
Safety Statements  26-36/37/39
Hazard Note  Irritant

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0034752 SORT-PGRN interaction inhibitor 1 99.37% 100957-85-5 100mg $54 2026-06-04 Buy
ChemScene CS-0034752 SORT-PGRN interaction inhibitor 1 99.37% 100957-85-5 250mg $97 2026-06-04 Buy
Matrix Scientific 303124 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid 100957-85-5 100.00mg $43 2026-05-19 Buy
Matrix Scientific 303124 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid 100957-85-5 250.00mg $62 2026-05-19 Buy
Matrix Scientific 303124 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid 100957-85-5 1.00g $73 2026-05-19 Buy
Product number Packaging Price Buy
CS-0034752 100mg $54 Buy
CS-0034752 250mg $97 Buy
303124 100.00mg $43 Buy
303124 250.00mg $62 Buy
303124 1.00g $73 Buy

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid Chemical Properties, Uses, Production

Uses

SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].

References

[1] Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403. DOI:10.1016/j.bmcl.2020.127403

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid Suppliers

Global Suppliers ( 54)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3987 55
Thermo Fisher Scientific 800-810-5118 cnchemical@thermofisher.com China 17752 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Changsha Luxing Bio-Chem Technology Co., Ltd. 0731-88827538 15574813303 luxingbc@126.com China 1975 65
NovoChemy Ltd. 86-(0)21-31261262 373522135 sales@novochemy.com China 6491 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
JiangYin Ruisheng Chemical Co., Ltd. 13003356808 1485751188@qq.com China 403 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Wuhan TCASChem Technology Co., Ltd. 55
Thermo Fisher Scientific 75
9ding chemical ( Shanghai) Limited 55
Changsha Luxing Bio-Chem Technology Co., Ltd. 65
NovoChemy Ltd. 58
Amadis Chemical Company Limited 58
JiangYin Ruisheng Chemical Co., Ltd. 55

View Latest Price from 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SORT-PGRN interaction inhibitor 1 pictures 2026-07-14 SORT-PGRN interaction inhibitor 1
100957-85-5
 $29.00 99.56% 10g TargetMol Chemicals Inc.

1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid Spectrum

1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID(100957-85-5)1HNMR

100957-85-5 (1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid) Related Search:

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1of3

BUTTPARK 153\57-04 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid, 95+% 2-benzyl-5-tert-butylpyrazole-3-carboxylic acid 2-Benzyl-5-tert-butyl-2H-pyrazole-3-carboxylic acid 1H-Pyrazole-5-carboxylic acid, 3-(1,1-dimethylethyl)-1-(phenylmethyl)- SORT-PGRN interaction inhibitor 1 inhibit,PPI,Inhibitor,sortilin,SORTPGRN interaction inhibitor 1,progranulin,PGRN,Neurotensin Receptor,SORT-PGRN interaction inhibitor 1,SORT PGRN interaction inhibitor 1 1-Benzyl-3-(tert-butyl)-1H-pyrazole-5-carboxylic acid 100957-85-5 CARBOXYLIC ACID